| Insider Transactions Reported - Last Two Years |
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| Date | Insider | Shares | Type | Transaction | Value* |
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| Jan 29, 2013 | AFEYAN NOUBARDirector | 2,000,000 | Indirect | Purchase at $2 per share. | 4,000,000 | | Jan 29, 2013 | PAPADOPOULOS STELIOSDirector | 250,000 | Direct | Purchase at $2 per share. | 500,000 | | Nov 18, 2012 | POSNER BRIAN SDirector | 10,000 | Direct | Purchase at $1.17 per share. | 11,700 | | Nov 14, 2012 | BANCEL STEPHANEOfficer | 100,000 | Direct | Purchase at $1.26 per share. | 126,000 | | Sep 12, 2012 | BANCEL STEPHANEOfficer | 1,381 | Direct | Purchase at $3.70 per share. | 5,109 | | Aug 20, 2012 | AFEYAN NOUBARDirector | 298,137 | Indirect | Disposition (Non Open Market) at $0 per share. | N/A | | Aug 19, 2012 | AFEYAN NOUBARDirector | 21,619 | Indirect | Option Exercise at $0.02 - $0.03 per share. | N/A | | Aug 19, 2012 | AFEYAN NOUBARDirector | 82 | Indirect | Sale at $5.83 per share. | 478 | | Jun 7, 2012 | MUNTENDAM PIETEROfficer | 3,965 | Direct | Sale at $5.29 per share. | 20,974 | | Jun 6, 2012 | MUNTENDAM PIETEROfficer | 30,021 | Direct | Sale at $5.50 per share. | 165,115 | | May 29, 2012 | MUNTENDAM PIETEROfficer | 100,000 | Direct | Option Exercise at $0.90 per share. | 90,000 | | May 22, 2012 | BOUVIER ERICOfficer | 10,000 | Direct | Purchase at $3.95 per share. | 39,500 | | May 22, 2012 | AFEYAN NOUBARDirector | 130,867 | Indirect | Disposition (Non Open Market) at $0 per share. | N/A | | May 21, 2012 | POSNER BRIAN SDirector | 10,000 | Direct | Purchase at $4.04 per share. | 40,400 | | May 20, 2012 | AFEYAN NOUBARDirector | 26,080 | Indirect | Option Exercise at $0.02 - $0.03 per share. | N/A | | May 20, 2012 | AFEYAN NOUBARDirector | 141 | Indirect | Sale at $3.95 per share. | 556 | | May 16, 2012 | BANCEL STEPHANEOfficer | 5,008 | Direct | Purchase at $3.84 per share. | 19,230 | | Apr 16, 2012 | VAN DER MEER PIETERBeneficial Owner (10% or more) | 200,000 | Indirect | Sale at $6.60 per share. | 1,320,000 | | Mar 18, 2012 | ADOURIAN ARAM S.Officer | 7,009 | Direct | Option Exercise at $0.90 per share. | 6,308 | | Feb 21, 2012 | BANCEL STEPHANEOfficer | 2,778 | Direct | Purchase at $0 per share. | N/A | | Nov 28, 2011 | PAPADOPOULOS STELIOSDirector | 151,616 | Direct | Option Exercise at $0.02 - $0.03 per share. | N/A | | Nov 28, 2011 | PAPADOPOULOS STELIOSDirector | 1,078 | Direct | Sale at $4.01 per share. | 4,322 | | Nov 8, 2011 | PAPADOPOULOS STELIOSDirector | 336,441 | Direct | Option Exercise at $0.90 per share. | 302,796 | | Sep 18, 2011 | AFEYAN NOUBARDirector | 193,133 | Indirect | Disposition (Non Open Market) at $0 per share. | N/A | | Sep 11, 2011 | BANCEL STEPHANEOfficer | 6,000 | Direct | Purchase at $3.63 per share. | 21,780 | | Sep 8, 2011 | BANCEL STEPHANEOfficer | 4,000 | Direct | Purchase at $4.30 per share. | 17,200 | | Sep 7, 2011 | BANCEL STEPHANEOfficer | 4,000 | Direct | Purchase at $4.40 per share. | 17,600 | | Aug 31, 2011 | MUNTENDAM PIETEROfficer | 2,803 | Direct | Option Exercise at $0.03 per share. | 84 | | Aug 31, 2011 | MUNTENDAM PIETEROfficer | 14 | Direct | Sale at $6.29 per share. | 88 |
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| Data provided by EDGAR Online |
* = Where indicated, some values are estimates. 1= Potential proceeds estimated by the filer. 2= Estimated based on the average of multiple prices reported. 3= Multiple dates reported. Most recent date shown.
Currency in USD.
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