| INSIDER TRANSACTIONS REPORTED - LAST TWO YEARS |
| Date | Insider | Shares | Type | Transaction | Value* | | 27-Apr-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 2,970,000 | Indirect | Sale at $1.15 per share. | $3,415,499 | | 3-Feb-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 8,921,716 | Indirect | Statement of Ownership | N/A | | 3-Feb-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | 5,336,336 | Direct | Statement of Ownership | N/A | | 30-Dec-08 | MCNAB JAMES R
Director | 25,000 | Direct | Disposition (Non Open Market) at $0 per share. | N/A | | 24-Oct-08 | GRAY MICHAEL
Officer | 79,113 | Direct | Acquisition (Non Open Market) at $0.01 per share. | $791 | | 1-Oct-08 | GRAY MICHAEL
Officer | 7,500 | Direct | Option Exercise at $1.09 per share. | $8,175 | | 1-Oct-08 | PASSERI DANIEL R
Officer | 20,000 | Direct | Option Exercise at $1.09 per share. | $21,800 | | 7-Aug-08 | PASSERI DANIEL R
Officer | 20,000 | Direct | Purchase at $1.55 per share. | $31,000 | | 6-Aug-08 | MCNAB JAMES R
Director | 50,000 | Indirect | Purchase at $1.56 per share. | $78,000 | | 6-Jun-08 | MCNAB JAMES R
Director | 50,000 | Direct | Purchase at $1.36 - $1.48 per share. | $71,0002 | | 15-Apr-08 | RA CAPITAL MANAGEMENT, LLC
Beneficial Owner (10% or more) | 1,300,000 | Indirect | Sale at $1.40 per share. | $1,820,000 |
|
* = Where indicated, some values are estimates.
1 = Potential proceeds estimated by the filer.
2 = Estimated based on the average of multiple prices reported.
3 = Multiple dates reported. Most recent date shown. |
|
1.48% Nasdaq 
Insider Transactions
