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    Pacira Pharmaceuticals, Inc. (PCRX)

    -NasdaqGS
    98.84 Up 3.45(3.62%) 3:21PM EST - Nasdaq Real Time Price
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    Insider TransactionsGet Insider Transactions for:
    Net Share Purchase Activity
    Insider Purchases - Last 6 Months
     SharesTrans
    PurchasesN/A0
    Sales749,20723
    Net Shares Purchased
    (Sold)
    (749,207)23
    Total Insider Shares Held2.59MN/A
    % Net Shares Purchased
    (Sold)
    (22.4%)N/A
    Net Institutional Purchases - Prior Qtr to Latest Qtr
     Shares
    Net Shares Purchased
    (Sold)
    (2,006,950)
    % Change in Institutional Shares Held(5.7%)
    Data provided by Thomson Financial


    Insider Transactions Reported - Last Two Years
    DateInsiderSharesTypeTransactionValue*
    Feb 6, 2015SCIBETTA JAMES SOfficer15,000DirectAutomatic Sale at $110.17 - $112.91 per share.1,673,0002
    Feb 6, 2015SCIBETTA JAMES SOfficer15,000DirectOption Exercise at $1.61 per share.24,150
    Jan 15, 2015STACK DAVID MOfficer15,000DirectOption Exercise at $1.61 per share.24,150
    Jan 15, 2015STACK DAVID MOfficer15,000DirectAutomatic Sale at $97.30 - $98.74 per share.1,470,0002
    Jan 12, 2015HASTINGS PAUL JDirector2,500DirectOption Exercise at $13.98 per share.34,950
    Jan 12, 2015HASTINGS PAUL JDirector2,500DirectAutomatic Sale at $94.06 per share.235,150
    Dec 29, 2014LONGENECKER JOHN P PHDDirector1,000DirectOption Exercise at $29.90 per share.29,900
    Dec 29, 2014LONGENECKER JOHN P PHDDirector1,000DirectAutomatic Sale at $93.32 per share.93,320
    Dec 5, 2014WINGER DENNIS LDirector2,645DirectPurchase at $94.54 per share.250,058
    Nov 7, 2014SCIBETTA JAMES SOfficer15,000DirectAutomatic Sale at $86.13 - $90.33 per share.1,323,0002
    Nov 7, 2014SCIBETTA JAMES SOfficer15,000DirectOption Exercise at $1.61 per share.24,150
    Nov 7, 2014MARKVICKA TAUNIAOfficer230IndirectPurchase at $86.62 per share.19,922
    Nov 3, 2014KRONENFELD MARK A.Director850DirectPurchase at $90.48 per share.76,908
    Oct 15, 2014STACK DAVID MOfficer15,000DirectAutomatic Sale at $96.60 - $101.2 per share.1,483,0002
    Oct 15, 2014STACK DAVID MOfficer15,000DirectOption Exercise at $1.61 per share.24,150
    Oct 10, 2014HASTINGS PAUL JDirector2,500DirectOption Exercise at $13.98 per share.34,950
    Oct 10, 2014HASTINGS PAUL JDirector2,500DirectAutomatic Sale at $94.87 per share.237,175
    Sep 29, 2014LONGENECKER JOHN P PHDDirector1,000DirectOption Exercise at $29.90 per share.29,900
    Sep 29, 2014LONGENECKER JOHN P PHDDirector1,000DirectAutomatic Sale at $96.40 per share.96,400
    Aug 29, 2014WICKI ANDREASDirector10,481IndirectSale at $108.15 per share.1,133,520
    Aug 28, 2014WICKI ANDREASDirector11,013IndirectSale at $108.06 per share.1,190,064
    Aug 27, 2014WICKI ANDREASDirector1,606IndirectSale at $108.05 per share.173,528
    Aug 26, 2014WICKI ANDREASDirector24,207IndirectSale at $108.11 per share.2,617,018
    Aug 25, 2014WICKI ANDREASDirector30,000IndirectSale at $108.07 per share.3,242,100
    Aug 11, 2014WICKI ANDREASDirector67,900IndirectSale at $101.20 - $101.82 per share.6,893,0002
    Aug 8, 2014SCIBETTA JAMES SOfficer15,000DirectOption Exercise at $1.61 per share.24,150
    Aug 8, 2014SCIBETTA JAMES SOfficer15,000DirectAutomatic Sale at $99.22 - $99.83 per share.1,493,0002
    Aug 8, 2014WICKI ANDREASDirector82,100IndirectSale at $101 per share.8,292,100
    Aug 7, 2014PATOU GARYOfficer20,000DirectAutomatic Sale at $100.26 per share.2,005,200
    Aug 7, 2014PATOU GARYOfficer20,000DirectOption Exercise at $1.61 - $11.68 per share.N/A
    Jul 15, 2014STACK DAVID MOfficer15,000DirectAutomatic Sale at $86.28 - $88.23 per share.1,309,0002
    Jul 15, 2014STACK DAVID MOfficer15,000DirectOption Exercise at $1.61 per share.24,150
    Jul 14, 2014PATOU GARYOfficer29,700DirectAutomatic Sale at $86.91 - $87.58 per share.2,591,0002
    Jul 14, 2014PATOU GARYOfficer30,000DirectOption Exercise at $1.61 - $10.81 per share.N/A
    Jul 10, 2014HASTINGS PAUL JDirector2,500DirectAutomatic Sale at $82.46 - $85.96 per share.211,0002
    Jul 10, 2014HASTINGS PAUL JDirector2,500DirectOption Exercise at $13.98 per share.34,950
    Jun 30, 2014LONGENECKER JOHN P PHDDirector1,000DirectOption Exercise at $29.90 per share.29,900
    Jun 30, 2014LONGENECKER JOHN P PHDDirector1,000DirectAutomatic Sale at $91.60 per share.91,600
    Jun 9, 2014WICKI ANDREASDirector68,000IndirectAutomatic Sale at $84.55 - $86.43 per share.5,813,0002
    Jun 6, 2014WICKI ANDREASDirector40,200IndirectAutomatic Sale at $82.71 per share.3,324,942
    Jun 5, 2014WICKI ANDREASDirector23,200IndirectAutomatic Sale at $82.53 per share.1,914,696
    Jun 4, 2014WICKI ANDREASDirector4,500IndirectAutomatic Sale at $82.40 per share.370,800
    Jun 3, 2014WICKI ANDREASDirector57,400IndirectSale at $80.72 per share.4,633,328
    Jun 2, 2014WICKI ANDREASDirector10,600IndirectAutomatic Sale at $80.52 per share.853,511
    May 27, 2014WICKI ANDREASDirector64,400IndirectAutomatic Sale at $77.93 per share.5,018,692
    May 21, 2014WICKI ANDREASDirector3,600IndirectAutomatic Sale at $77.80 per share.280,080
    May 12, 2014PATOU GARYOfficer10,000DirectAutomatic Sale at $75 per share.750,000
    May 12, 2014PATOU GARYOfficer10,000DirectOption Exercise at $5.49 per share.54,899
    May 9, 2014PATOU GARYOfficer20,000DirectOption Exercise at $1.61 - $5.49 per share.N/A
    May 9, 2014BREGE LAURADirector10,000DirectOption Exercise at $10.81 - $13.98 per share.N/A
    May 9, 2014STACK DAVID MOfficer25,000DirectOption Exercise at $1.61 per share.40,250
    May 9, 2014BREGE LAURADirector10,000DirectAutomatic Sale at $73.57 - $74.67 per share.741,0002
    May 9, 2014PATOU GARYOfficer20,000DirectAutomatic Sale at $74.08 per share.1,481,600
    May 9, 2014STACK DAVID MOfficer25,000DirectAutomatic Sale at $73.40 - $74.8 per share.1,853,0002
    May 8, 2014WICKI ANDREASDirector23,220IndirectAutomatic Sale at $75.76 per share.1,759,147
    May 8, 2014SCIBETTA JAMES SOfficer15,000DirectAutomatic Sale at $74.27 - $75.8 per share.1,126,0002
    May 8, 2014SCIBETTA JAMES SOfficer15,000DirectOption Exercise at $1.61 per share.24,150
    May 7, 2014WICKI ANDREASDirector600IndirectAutomatic Sale at $75.64 per share.45,384
    May 6, 2014WICKI ANDREASDirector44,180IndirectAutomatic Sale at $75.78 per share.3,347,960
    Mar 28, 2014LONGENECKER JOHN P PHDDirector1,000DirectOption Exercise at $29.90 per share.29,900
    Mar 28, 2014LONGENECKER JOHN P PHDDirector1,000DirectAutomatic Sale at $64.63 per share.64,629
    Mar 11, 2014PATOU GARYOfficer504IndirectAcquisition (Non Open Market) at $0 per share.N/A
    Mar 11, 2014STACK DAVID MOfficer221DirectAcquisition (Non Open Market) at $0 per share.N/A
    Mar 6, 2014WICKI ANDREASDirector2,200IndirectSale at $80.11 per share.176,242
    Mar 5, 2014WICKI ANDREASDirector22,687IndirectSale at $80.16 per share.1,818,589
    Dec 30, 2013STACK DAVID MOfficer15,000DirectAutomatic Sale at $55.84 per share.837,600
    Dec 30, 2013LONGENECKER JOHN P PHDDirector2,500DirectAutomatic Sale at $55.55 per share.138,875
    Dec 30, 2013LONGENECKER JOHN P PHDDirector2,500DirectOption Exercise at $1.61 per share.4,025
    Dec 30, 2013STACK DAVID MOfficer15,000DirectOption Exercise at $1.61 per share.24,150
    Dec 30, 2013SCIBETTA JAMES SOfficer10,000DirectAutomatic Sale at $55.55 per share.555,500
    Dec 30, 2013SCIBETTA JAMES SOfficer10,000DirectOption Exercise at $1.61 per share.16,100
    Nov 18, 2013PATOU GARYOfficer83IndirectAcquisition (Non Open Market) at $0 per share.N/A
    Nov 18, 2013STACK DAVID MOfficer414DirectAcquisition (Non Open Market) at $0 per share.N/A
    Nov 6, 2013MARKVICKA TAUNIAOfficer50,000DirectOption Exercise at $10.81 per share.540,500
    Nov 6, 2013MARKVICKA TAUNIAOfficer50,000DirectAutomatic Sale at $50.60 - $53.61 per share.2,605,0002
    Oct 1, 2013PATOU GARYOfficer20,000DirectAutomatic Sale at $48.92 per share.978,399
    Oct 1, 2013PATOU GARYOfficer20,000DirectOption Exercise at $1.61 per share.32,200
    Sep 30, 2013STACK DAVID MOfficer15,000DirectAutomatic Sale at $47.01 - $47.55 per share.709,0002
    Sep 30, 2013LONGENECKER JOHN P PHDDirector2,500DirectAutomatic Sale at $46.74 per share.116,850
    Sep 30, 2013SCIBETTA JAMES SOfficer10,000DirectOption Exercise at $1.61 per share.16,100
    Sep 30, 2013STACK DAVID MOfficer15,000DirectOption Exercise at $1.61 per share.24,150
    Sep 30, 2013LONGENECKER JOHN P PHDDirector2,500DirectOption Exercise at $1.61 per share.4,025
    Sep 30, 2013SCIBETTA JAMES SOfficer10,000DirectAutomatic Sale at $46.74 per share.467,400
    Sep 25, 2013MARKVICKA TAUNIAOfficer10,000DirectAutomatic Sale at $47 per share.470,000
    Sep 25, 2013MARKVICKA TAUNIAOfficer10,000DirectOption Exercise at $5.49 per share.54,899
    Sep 11, 2013WICKI ANDREASDirector17,783IndirectSale at $37.25 per share.662,416
    Sep 11, 2013WICKI ANDREASDirector79,033IndirectOption Exercise at $2.69 - $13.44 per share.N/A
    Sep 11, 2013KRONENFELD MARK A.Director1,000DirectPurchase at $37.01 per share.37,010
    Aug 14, 2013MARKVICKA TAUNIAOfficer14,700DirectOption Exercise at $1.61 per share.23,667
    Aug 14, 2013MARKVICKA TAUNIAOfficer14,700DirectAutomatic Sale at $37 per share.543,900
    Jul 22, 2013WICKI ANDREASDirector19,938IndirectAutomatic Sale at $35.28 per share.703,412
    Jul 19, 2013WICKI ANDREASDirector56,020IndirectAutomatic Sale at $34.98 per share.1,959,579
    Jul 18, 2013WICKI ANDREASDirector4,042IndirectAutomatic Sale at $34.80 per share.140,661
    Jul 17, 2013WICKI ANDREASDirector21,518IndirectAutomatic Sale at $33.20 per share.714,397
    Jul 16, 2013WICKI ANDREASDirector350IndirectAutomatic Sale at $33.20 per share.11,620
    Jul 15, 2013WICKI ANDREASDirector48,132IndirectAutomatic Sale at $33.28 per share.1,601,832
    Jul 12, 2013MARKVICKA TAUNIAOfficer29,754DirectAutomatic Sale at $32 per share.952,128
    Jul 12, 2013MARKVICKA TAUNIAOfficer29,754DirectOption Exercise at $1.61 per share.47,903
    Jul 11, 2013WICKI ANDREASDirector80,000IndirectAutomatic Sale at $31.48 per share.2,518,400
    Jul 5, 2013WICKI ANDREASDirector44,021IndirectAutomatic Sale at $30.80 per share.1,355,846
    Jul 3, 2013WICKI ANDREASDirector50,000IndirectAutomatic Sale at $30.67 per share.1,533,500
    Jul 2, 2013PATOU GARYOfficer10,000DirectOption Exercise at $1.61 per share.16,100
    Jul 2, 2013WICKI ANDREASDirector60,597IndirectAutomatic Sale at $29.85 per share.1,808,820
    Jul 2, 2013PATOU GARYOfficer10,000DirectAutomatic Sale at $30 per share.300,000
    Jul 1, 2013PATOU GARYOfficer30,000DirectOption Exercise at $1.61 per share.48,300
    Jul 1, 2013PATOU GARYOfficer30,000DirectAutomatic Sale at $29.25 per share.877,500
    Jul 1, 2013WICKI ANDREASDirector3,851IndirectAutomatic Sale at $29.85 per share.114,952
    Jun 28, 2013STACK DAVID MOfficer15,000DirectAutomatic Sale at $28.73 per share.430,950
    Jun 28, 2013LONGENECKER JOHN P PHDDirector2,000DirectAutomatic Sale at $28.09 per share.56,180
    Jun 28, 2013SCIBETTA JAMES SOfficer10,000DirectOption Exercise at $1.61 per share.16,100
    Jun 28, 2013LONGENECKER JOHN P PHDDirector2,000DirectOption Exercise at $1.61 per share.3,220
    Jun 28, 2013STACK DAVID MOfficer15,000DirectOption Exercise at $1.61 per share.24,150
    Jun 28, 2013SCIBETTA JAMES SOfficer10,000DirectAutomatic Sale at $28.05 per share.280,500
    Jun 24, 2013MIDDLETON FRED ADirector5,900IndirectAutomatic Sale at $28.70 per share.169,330
    Jun 21, 2013MIDDLETON FRED ADirector70,000IndirectAutomatic Sale at $28.49 - $29.22 per share.2,020,0002
    Jun 20, 2013MIDDLETON FRED ADirector66,100IndirectAutomatic Sale at $28.93 per share.1,912,273
    Jun 19, 2013MIDDLETON FRED ADirector48,400IndirectAutomatic Sale at $29.76 per share.1,440,384
    Jun 19, 2013WICKI ANDREASDirector35,407IndirectAutomatic Sale at $29.90 per share.1,058,669
    Jun 18, 2013MIDDLETON FRED ADirector29,600IndirectAutomatic Sale at $29.48 per share.872,608
    Jun 17, 2013WICKI ANDREASDirector50,145IndirectAutomatic Sale at $29.86 per share.1,497,329
    Jun 13, 2013PRATT JOHNOfficer20,107DirectOption Exercise at $8.73 - $10.81 per share.N/A
    Jun 13, 2013EVNIN LUKEDirector20,311DirectAutomatic Sale at $30.07 per share.610,751
    Jun 13, 2013PRATT JOHNOfficer20,107DirectSale at $30 per share.603,210
    Jun 12, 2013WICKI ANDREASDirector4,409IndirectSale at $30 per share.132,270
    Jun 12, 2013EVNIN LUKEDirector2,435DirectAutomatic Sale at $30 per share.73,050
    Jun 12, 2013PRATT JOHNOfficer925DirectOption Exercise at $10.81 per share.9,999
    Jun 12, 2013PRATT JOHNOfficer925DirectSale at $30 per share.27,750
    Jun 11, 2013PRATT JOHNOfficer12,945DirectOption Exercise at $10.81 per share.139,935
    Jun 11, 2013PRATT JOHNOfficer12,945DirectSale at $30 per share.388,350
    Jun 11, 2013WICKI ANDREASDirector9,000IndirectSale at $30 per share.270,000
    Jun 10, 2013PRATT JOHNOfficer5,398DirectSale at $30 per share.161,940
    Jun 10, 2013WICKI ANDREASDirector2,500IndirectSale at $30 per share.75,000
    Jun 10, 2013PRATT JOHNOfficer5,398DirectOption Exercise at $10.81 per share.58,352
    Jun 5, 2013MIDDLETON FRED ADirector557,845IndirectDisposition (Non Open Market) at $0 per share.N/A
    Jun 5, 2013MIDDLETON FRED ADirector7,433DirectAcquisition (Non Open Market) at $0 per share.N/A
    Jun 5, 2013WICKI ANDREASDirector2,500IndirectSale at $30 per share.75,000
    Jun 4, 2013WICKI ANDREASDirector13,000IndirectSale at $30.31 per share.394,030
    Jun 3, 2013EVNIN LUKEDirector82,072IndirectAutomatic Sale at $30 per share.2,462,160
    Jun 3, 2013WICKI ANDREASDirector1,900IndirectSale at $30 per share.57,000
    May 31, 2013WICKI ANDREASDirector3,033IndirectAutomatic Sale at $30 per share.90,990
    May 31, 2013EVNIN LUKEDirector9,935IndirectAutomatic Sale at $30 per share.298,050
    May 30, 2013WICKI ANDREASDirector2,500IndirectAutomatic Sale at $30 per share.75,000
    May 30, 2013EVNIN LUKEDirector44,582IndirectAutomatic Sale at $30 per share.1,337,460
    May 29, 2013EVNIN LUKEDirector20,411IndirectAutomatic Sale at $30 per share.612,330
    May 28, 2013EVNIN LUKEDirector195,117IndirectAutomatic Sale at $30.62 - $32.14 per share.6,123,0002
    May 22, 2013WICKI ANDREASDirector18,471IndirectAutomatic Sale at $30 per share.554,130
    May 22, 2013EVNIN LUKEDirector7,340IndirectAutomatic Sale at $30 per share.220,200
    May 20, 2013WICKI ANDREASDirector14,374IndirectAutomatic Sale at $30 per share.431,220
    May 20, 2013EVNIN LUKEDirector13,550IndirectAutomatic Sale at $30 per share.406,500
    May 15, 2013HASTINGS PAUL JDirector853DirectPurchase at $29.30 per share.24,992
    Apr 24, 2013WICKI ANDREASDirector401IndirectAutomatic Sale at $30.04 per share.12,046
    Apr 24, 2013EVNIN LUKEDirector6,303IndirectAutomatic Sale at $30.04 per share.189,342
    Apr 23, 2013EVNIN LUKEDirector108,115IndirectAutomatic Sale at $30 per share.3,243,450
    Apr 23, 2013WICKI ANDREASDirector15,646IndirectAutomatic Sale at $30 per share.469,380
    Apr 15, 2013WICKI ANDREASDirector6,400IndirectAutomatic Sale at $30 per share.192,000
    Apr 15, 2013EVNIN LUKEDirector2,575IndirectAutomatic Sale at $30 per share.77,250
    Apr 12, 2013EVNIN LUKEDirector3,416IndirectSale at $29.30 per share.100,088
    Apr 12, 2013PATOU GARYOfficer10,000DirectAutomatic Sale at $30 per share.300,000
    Apr 12, 2013EVNIN LUKEDirector10,000IndirectAutomatic Sale at $30 per share.300,000
    Apr 12, 2013PATOU GARYOfficer10,000DirectOption Exercise at $1.61 per share.16,100
    Apr 12, 2013EVNIN LUKEDirector37,192IndirectOption Exercise at $2.69 per share.100,046
    Apr 12, 2013WICKI ANDREASDirector34,294IndirectAutomatic Sale at $30 per share.1,028,820
    Apr 11, 2013WICKI ANDREASDirector600IndirectAutomatic Sale at $30 per share.18,000
    Apr 1, 2013PATOU GARYOfficer30,000DirectOption Exercise at $1.61 per share.48,300
    Apr 1, 2013PATOU GARYOfficer30,000DirectAutomatic Sale at $27.75 - $28.82 per share.849,0002
    Mar 28, 2013SCIBETTA JAMES SOfficer10,000DirectAutomatic Sale at $28.49 per share.284,900
    Mar 28, 2013SCIBETTA JAMES SOfficer10,000DirectOption Exercise at $1.61 per share.16,100
    Mar 28, 2013LONGENECKER JOHN P PHDDirector2,000DirectOption Exercise at $1.61 per share.3,220
    Mar 28, 2013LONGENECKER JOHN P PHDDirector2,000DirectAutomatic Sale at $28.49 per share.56,980
    Mar 28, 2013STACK DAVID MOfficer15,000DirectOption Exercise at $1.61 per share.24,150
    Mar 28, 2013STACK DAVID MOfficer15,000DirectAutomatic Sale at $28.66 per share.429,900
    Mar 25, 2013WICKI ANDREASDirector165,541IndirectAutomatic Sale at $28.28 per share.4,681,499
    Mar 25, 2013HBM HEALTHCARE INVESTMENTS (CAYMAN) LTD.Beneficial Owner (10% or more)165,541DirectAutomatic Sale at $28.28 per share.4,681,499
    Mar 22, 2013HBM HEALTHCARE INVESTMENTS (CAYMAN) LTD.Beneficial Owner (10% or more)113,928DirectAutomatic Sale at $27.52 per share.3,135,298
    Mar 22, 2013WICKI ANDREASDirector113,928IndirectAutomatic Sale at $27.52 per share.3,135,298
    Mar 21, 2013WICKI ANDREASDirector11,431IndirectAutomatic Sale at $27.50 per share.314,352
    Mar 21, 2013HBM HEALTHCARE INVESTMENTS (CAYMAN) LTD.Beneficial Owner (10% or more)11,431DirectAutomatic Sale at $27.50 per share.314,352
    Mar 19, 2013WICKI ANDREASDirector9,100IndirectAutomatic Sale at $27.86 per share.253,526
    Mar 19, 2013SANDERLING VENTURE PARTNERS VI LPDirector84,589DirectAutomatic Sale at $26.95 - $27.66 per share.2,310,0002
    Mar 19, 2013HBM HEALTHCARE INVESTMENTS (CAYMAN) LTD.Beneficial Owner (10% or more)9,100DirectAutomatic Sale at $27.86 per share.253,526
    Mar 18, 2013EVNIN LUKEDirector500,000IndirectSale at $28.44 per share.14,220,000
    Mar 18, 2013SANDERLING VENTURE PARTNERS VI LPDirector165,411DirectAutomatic Sale at $28.19 - $29.2 per share.4,746,0002
    Mar 18, 2013WICKI ANDREASDirector400,000IndirectAutomatic Sale at $28.19 per share.11,276,000
    Mar 18, 2013HBM HEALTHCARE INVESTMENTS (CAYMAN) LTD.Beneficial Owner (10% or more)400,000DirectAutomatic Sale at $28.19 per share.11,276,000
    Mar 18, 2013STACK DAVID MOfficer573DirectAcquisition (Non Open Market) at $0 per share.N/A
    Mar 15, 2013SANDERLING VENTURE PARTNERS VI LPDirector200,000DirectDisposition (Non Open Market) at $0 per share.N/A
    Mar 15, 2013SANDERLING VENTURE PARTNERS VI LPDirector25,133DirectAcquisition (Non Open Market) at $0 per share.N/A
    Mar 15, 2013SANDERLING VENTURE PARTNERS VI LPBeneficial Owner (10% or more)200,000DirectAcquisition (Non Open Market) at $0 per share.N/A
    Mar 15, 2013SANDERLING VENTURE PARTNERS VI LPBeneficial Owner (10% or more)1,000,000DirectDisposition (Non Open Market) at $0 per share.N/A
    Mar 14, 2013RIKER LAUREN BULLAROOfficer10,000DirectOption Exercise at $10.34 per share.103,400
    Mar 14, 2013RIKER LAUREN BULLAROOfficer10,000DirectSale at $30 per share.300,000
    Mar 12, 2013PRATT JOHNOfficer9,375DirectOption Exercise at $8.73 per share.81,843
    Mar 12, 2013PRATT JOHNOfficer9,375DirectSale at $28.46 per share.266,812
    Mar 11, 2013SANDERLING VENTURE PARTNERS VI LPBeneficial Owner (10% or more)348,951DirectSale at $27.86 per share.9,721,774
    Mar 11, 2013EVNIN LUKEDirector500,000IndirectSale at $27.86 per share.13,930,000
    Mar 11, 2013WICKI ANDREASDirector500,000IndirectSale at $27.86 per share.13,930,000
    Mar 11, 2013KAILIAN VAUGHN MOther500,000IndirectSale at $27.86 per share.13,930,000
    Mar 11, 2013MPM BIOVENTURES IV QP LPOther500,000IndirectSale at $27.86 per share.13,930,000
    Mar 11, 2013HBM HEALTHCARE INVESTMENTS (CAYMAN) LTD.Beneficial Owner (10% or more)500,000DirectSale at $27.86 per share.13,930,000
    Mar 7, 2013SANDERLING VENTURE PARTNERS VI LPBeneficial Owner (10% or more)25,560DirectSale at $25.92 per share.662,515
    Mar 7, 2013SANDERLING VENTURE PARTNERS VI LPBeneficial Owner (10% or more)79,031DirectOption Exercise at $2.69 - $13.44 per share.N/A
    Data provided by EDGAR Online
    * = Where indicated, some values are estimates.
    1= Potential proceeds estimated by the filer.
    2= Estimated based on the average of multiple prices reported.
    3= Multiple dates reported. Most recent date shown.

    Currency in USD.



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