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 Dow Down0.10% Nasdaq Up0.23%

Isis Pharmaceuticals, Inc. (ISIS)

-NasdaqGS
34.01 Down 0.56(1.62%) Apr 17, 4:00PM EDT
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Key StatisticsGet Key Statistics for:
Data provided by Capital IQ, except where noted.
Valuation Measures 
Market Cap (intraday)5:3.99B
Enterprise Value (Apr 19, 2014)3:3.50B
Trailing P/E (ttm, intraday):N/A
Forward P/E (fye Dec 31, 2015)1:N/A
PEG Ratio (5 yr expected)1:-2.20
Price/Sales (ttm):27.53
Price/Book (mrq):10.64
Enterprise Value/Revenue (ttm)3:23.75
Enterprise Value/EBITDA (ttm)6:-98.32
Financial Highlights 
Fiscal Year
Fiscal Year Ends:Dec 31
Most Recent Quarter (mrq):Dec 31, 2013
Profitability
Profit Margin (ttm):-41.17%
Operating Margin (ttm):-30.80%
Management Effectiveness
Return on Assets (ttm):-4.07%
Return on Equity (ttm):-21.61%
Income Statement
Revenue (ttm):147.29M
Revenue Per Share (ttm):1.33
Qtrly Revenue Growth (yoy):112.60%
Gross Profit (ttm):147.28M
EBITDA (ttm)6:-35.58M
Net Income Avl to Common (ttm):-60.64M
Diluted EPS (ttm):-0.55
Qtrly Earnings Growth (yoy):N/A
Balance Sheet
Total Cash (mrq):710.13M
Total Cash Per Share (mrq):6.06
Total Debt (mrq):232.57M
Total Debt/Equity (mrq):61.46
Current Ratio (mrq):7.52
Book Value Per Share (mrq):3.25
Cash Flow Statement
Operating Cash Flow (ttm):63.49M
Levered Free Cash Flow (ttm):-8.77M
View Financials
Income Statement - Balance Sheet - Cash Flow

Trading Information 
Stock Price History
Beta:1.58
52-Week Change3:61.18%
S&P500 52-Week Change3:20.97%
52-Week High (Feb 24, 2014)3:62.66
52-Week Low (May 9, 2013)3:18.27
50-Day Moving Average3:43.94
200-Day Moving Average3:41.41
Share Statistics
Avg Vol (3 month)3:1,950,570
Avg Vol (10 day)3:2,128,890
Shares Outstanding5:117.27M
Float:116.28M
% Held by Insiders1:0.89%
% Held by Institutions1:78.30%
Shares Short (as of Mar 31, 2014)3:12.53M
Short Ratio (as of Mar 31, 2014)3:5.50
Short % of Float (as of Mar 31, 2014)3:14.60%
Shares Short (prior month)3:12.56M
Dividends & Splits
Forward Annual Dividend Rate4:N/A
Forward Annual Dividend Yield4:N/A
Trailing Annual Dividend Yield3:N/A
Trailing Annual Dividend Yield3:N/A
5 Year Average Dividend Yield4:N/A
Payout Ratio4:N/A
Dividend Date3:N/A
Ex-Dividend Date4:N/A
Last Split Factor (new per old)2:N/A
Last Split Date3:N/A

See Key Statistics Help for definitions of terms used.
Abbreviation Guide: K = Thousands; M = Millions; B = Billions
mrq = Most Recent Quarter (as of Dec 31, 2013)
ttm = Trailing Twelve Months (as of Dec 31, 2013)
yoy = Year Over Year (as of Dec 31, 2013)
lfy = Last Fiscal Year (as of Dec 31, 2013)
fye = Fiscal Year Ending
1 Data provided by Thomson Reuters
2 Data provided by EDGAR Online
3 Data derived from multiple sources or calculated by Yahoo! Finance
4 Data provided by Morningstar, Inc.
5 Shares outstanding is taken from the most recently filed quarterly or annual report and Market Cap is calculated using shares outstanding.
6 EBITDA is calculated by Capital IQ using methodology that may differ from that used by a company in its reporting

Currency in USD.