Dow Up0.07% Nasdaq Up0.61%

Isis Pharmaceuticals, Inc. (ISIS)

52.75 Up 1.24(2.41%) Nov 26, 4:00PM EST
|After Hours : 52.75 0.00 (0.00%) Nov 26, 6:27PM EST
Key StatisticsGet Key Statistics for:
Data provided by Capital IQ, except where noted.
Valuation Measures 
Market Cap (intraday)5:6.23B
Enterprise Value (Nov 27, 2014)3:5.83B
Trailing P/E (ttm, intraday):N/A
Forward P/E (fye Dec 31, 2015)1:N/A
PEG Ratio (5 yr expected)1:-3.44
Price/Sales (ttm):35.47
Price/Book (mrq):17.63
Enterprise Value/Revenue (ttm)3:33.96
Enterprise Value/EBITDA (ttm)6:-94.54
Financial Highlights 
Fiscal Year
Fiscal Year Ends:Dec 31
Most Recent Quarter (mrq):Sep 30, 2014
Profit Margin (ttm):-54.98%
Operating Margin (ttm):-41.41%
Management Effectiveness
Return on Assets (ttm):-5.30%
Return on Equity (ttm):-25.28%
Income Statement
Revenue (ttm):171.55M
Revenue Per Share (ttm):1.46
Qtrly Revenue Growth (yoy):86.80%
Gross Profit (ttm):147.28M
EBITDA (ttm)6:-61.63M
Net Income Avl to Common (ttm):-94.31M
Diluted EPS (ttm):-0.81
Qtrly Earnings Growth (yoy):N/A
Balance Sheet
Total Cash (mrq):640.43M
Total Cash Per Share (mrq):5.42
Total Debt (mrq):234.76M
Total Debt/Equity (mrq):68.09
Current Ratio (mrq):6.35
Book Value Per Share (mrq):2.92
Cash Flow Statement
Operating Cash Flow (ttm):-78.89M
Levered Free Cash Flow (ttm):-32.18M
View Financials
Income Statement - Balance Sheet - Cash Flow

Trading Information 
Stock Price History
52-Week Change3:36.09%
S&P500 52-Week Change3:14.79%
52-Week High (Feb 24, 2014)3:62.66
52-Week Low (May 9, 2014)3:22.25
50-Day Moving Average3:45.22
200-Day Moving Average3:36.82
Share Statistics
Avg Vol (3 month)3:2,327,880
Avg Vol (10 day)3:1,329,780
Shares Outstanding5:118.14M
% Held by Insiders1:0.79%
% Held by Institutions1:88.80%
Shares Short (as of Nov 14, 2014)3:14.96M
Short Ratio (as of Nov 14, 2014)3:5.40
Short % of Float (as of Nov 14, 2014)3:15.00%
Shares Short (prior month)3:14.94M
Dividends & Splits
Forward Annual Dividend Rate4:N/A
Forward Annual Dividend Yield4:N/A
Trailing Annual Dividend Yield3:N/A
Trailing Annual Dividend Yield3:N/A
5 Year Average Dividend Yield4:N/A
Payout Ratio4:N/A
Dividend Date3:N/A
Ex-Dividend Date4:N/A
Last Split Factor (new per old)2:N/A
Last Split Date3:N/A

See Key Statistics Help for definitions of terms used.
Abbreviation Guide: K = Thousands; M = Millions; B = Billions
mrq = Most Recent Quarter (as of Sep 30, 2014)
ttm = Trailing Twelve Months (as of Sep 30, 2014)
yoy = Year Over Year (as of Sep 30, 2014)
lfy = Last Fiscal Year (as of Dec 31, 2013)
fye = Fiscal Year Ending
1 Data provided by Thomson Reuters
2 Data provided by EDGAR Online
3 Data derived from multiple sources or calculated by Yahoo! Finance
4 Data provided by Morningstar, Inc.
5 Shares outstanding is taken from the most recently filed quarterly or annual report and Market Cap is calculated using shares outstanding.
6 EBITDA is calculated by Capital IQ using methodology that may differ from that used by a company in its reporting

Currency in USD.