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    Alnylam Pharmaceuticals, Inc. (ALNY)

    -NasdaqGS
    57.00 Down 2.22(3.75%) Feb 10, 4:00PM EST
    Major HoldersGet Major Holders for:
    Breakdown
    % of Shares Held by All Insider and 5% Owners:13%
    % of Shares Held by Institutional & Mutual Fund Owners:79%
    % of Float Held by Institutional & Mutual Fund Owners:91%
    Number of Institutions Holding Shares:301

    Major Direct Holders (Forms 3 & 4)
    HolderSharesReported
    SANOFIN/AJan 29, 2015
    SCHIMMEL PAUL0Apr 21, 2015
    SHARP PHILIP A140,795Jun 1, 2015
    MARAGANORE JOHN122,825Jan 26, 2015
    GREENE BARRY E23,392May 26, 2015


    Top Institutional Holders
    HolderShares% OutValue*Reported
    Vanguard Group, Inc. (The)5,048,2215.96475,239,519Dec 31, 2015
    Baillie Gifford and Company2,727,7343.22256,788,876Dec 31, 2015
    Capital World Investors1,943,6032.29156,187,939Sep 30, 2015
    Ubs Global Asset Management Americas Inc1,911,5352.26153,610,954Sep 30, 2015
    BlackRock Fund Advisors1,903,7112.25152,982,217Sep 30, 2015
    BlackRock Institutional Trust Company, N.A.1,761,6142.08141,563,302Sep 30, 2015
    FMR, LLC12,692,26914.981,019,950,749Sep 30, 2015
    Wellington Management Company, LLP10,324,12612.18829,646,775Sep 30, 2015
    State Street Corporation1,547,3551.83124,345,449Sep 30, 2015
    Jennison Associates LLC1,482,2451.75119,113,209Sep 30, 2015

    Top Mutual Fund Holders
    HolderShares% OutValue*Reported
    Vanguard Specialized-Health Care Fund7,583,6108.95651,811,256Oct 31, 2015
    Fidelity Growth Company Fund4,923,8415.81512,374,884Nov 30, 2015
    Fidelity Select Portfolios - Biotechnology1,811,3782.14188,491,991Nov 30, 2015
    Vanguard Mid-Cap Index Fund1,393,1341.64111,952,249Sep 30, 2015
    Fidelity Series Growth Company Fund1,350,2511.59140,507,116Nov 30, 2015
    Vanguard Total Stock Market Index Fund1,203,4401.4296,708,439Sep 30, 2015
    iShares NASDAQ Biotechnology ETF1,117,0781.32116,243,134Nov 30, 2015
    First Trust NYSE Arca Biotechnology Index Fund944,5621.1175,905,003Sep 30, 2015
    Growth Fund Of America Inc865,0001.0281,431,099Dec 31, 2015
    Prudential Jennison Health Sciences Fd787,1110.9381,906,769Nov 30, 2015

    View Transactions for Insiders & Institutional Holders

    Value shown is computed using the security's price on the report date given.

    Currency in USD.