| Top Institutional Holders |
|---|
| Holder | Shares | % Out | Value* | Reported |
|---|
| Healthcor Management LP | 17,600,000 | 9.62 | 39,072,000 | Mar 31, 2013 | | State Street Corporation | 10,662,549 | 5.83 | 23,670,858 | Mar 31, 2013 | | S.A.C. Capital Advisors, LLC | 6,996,857 | 3.83 | 15,533,022 | Mar 31, 2013 | | Vanguard Group, Inc. (The) | 6,793,402 | 3.71 | 15,081,352 | Mar 31, 2013 | | BlackRock Institutional Trust Company, N.A. | 5,021,549 | 2.75 | 11,147,838 | Mar 31, 2013 | | Redmile Group, LLC | 4,508,797 | 2.47 | 10,009,529 | Mar 31, 2013 | | BlackRock Fund Advisors | 4,311,985 | 2.36 | 9,572,606 | Mar 31, 2013 | | FMR, LLC | 27,056,595 | 14.79 | 60,065,640 | Mar 31, 2013 | | Federated Investors, Inc. | 25,960,000 | 14.19 | 57,631,200 | Mar 31, 2013 | | Blair (William) & Company, L.L.C. | 3,572,265 | 1.95 | 7,930,428 | Mar 31, 2013 |
|
| Holder | Shares | % Out | Value* | Reported |
|---|
| Federated Kaufmann Small Cap Fund | 13,700,000 | 7.49 | 42,333,000 | Jan 31, 2013 | | Advanced Series Tr-AST/Federated Aggressive Growth Port | 12,260,000 | 6.70 | 34,941,000 | Dec 31, 2012 | | SPDR (R) Ser Tr-SPDR (R) S&P (R) Biotech ETF | 7,508,056 | 4.11 | 16,667,884 | Mar 31, 2013 | | Fidelity Dividend Growth Fund | 3,874,970 | 2.12 | 8,602,433 | Mar 31, 2013 | | Fidelity Small Cap Stock Fund | 3,227,200 | 1.76 | 9,972,048 | Jan 31, 2013 | | Fidelity Advisor Capital Development Fund | 2,844,511 | 1.56 | 6,314,814 | Mar 31, 2013 | | Vanguard Small-Cap Index Fund | 2,800,152 | 1.53 | 7,980,433 | Dec 31, 2012 | | iShares Russell 2000 Index Fund | 2,794,545 | 1.53 | 6,203,889 | Mar 31, 2013 | | Fidelity Small Cap Opportunities Fund | 2,648,790 | 1.45 | 8,184,761 | Jan 31, 2013 | | Fidelity Select Portfolios - Health Care | 2,500,000 | 1.37 | 5,550,000 | Mar 31, 2013 |
|
View Transactions for Insiders & Institutional Holders Value shown is computed using the security's price on the report date given. Currency in USD. |
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