| TOP INSTITUTIONAL HOLDERS |
| Holder | Shares | % Out | Value* | Reported | | Hartz Capital, Inc. | 2,300,000 | 4.11 | $5,382,000 | 30-Sep-09 | | Barclays Global Investors UK Holdings Ltd | 1,255,510 | 2.24 | $2,937,893 | 30-Sep-09 | | Susquehanna International Group, LLP | 1,179,800 | 2.11 | $2,760,732 | 30-Sep-09 | | BB BIOTECH AG | 801,811 | 1.43 | $1,876,237 | 30-Sep-09 | | Bailard, Inc. | 800,000 | 1.43 | $1,872,000 | 30-Sep-09 | | Timescape Global Capital Management, LLC | 714,600 | 1.28 | $1,672,164 | 30-Sep-09 | | RCM CAPITAL MANAGEMENT | 634,877 | 1.13 | $1,485,612 | 30-Sep-09 | | BAM Management, LLC | 467,319 | .83 | $1,093,526 | 30-Sep-09 | | GEODE CAPITAL MANAGEMENT, LLC | 241,640 | .43 | $565,437 | 30-Sep-09 | | Bank of New York Mellon Corporation | 205,437 | .37 | $480,722 | 30-Sep-09 |
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| Holder | Shares | % Out | Value* | Reported | | Allianz Fds-RCM Wellness Fd | 257,395 | .46 | $339,761 | 31-Aug-09 | | SPARTAN TOTAL MARKET INDEX FUND | 173,161 | .31 | $405,196 | 30-Sep-09 | | AXA PREMIER VIP MULTIMANAGER HEALTH CARE PORTFOLIO | 113,755 | .20 | $102,379 | 30-Jun-09 | | ENGEX INC | 85,500 | .15 | $76,950 | 30-Jun-09 | | SPARTAN EXTENDED MARKET INDEX FUND | 60,465 | .11 | $141,488 | 30-Sep-09 | | DFA U.S. MICRO CAP SERIES | 45,500 | .08 | $10,920 | 30-Apr-09 | | VANGUARD INSTITUTIONAL INDEX-INST TOTAL STOCK MARKET IND | 28,705 | .05 | $4,018 | 31-Mar-09 | | DFA U.S. Core Equity 2 Portfolio | 16,500 | .03 | $3,960 | 30-Apr-09 | | PRICE (T.ROWE) EXTENDED EQUITY MARKET INDEX FUND | 13,500 | .02 | $12,150 | 30-Jun-09 | | DFA U.S. Vector Equity Portfolio | 7,718 | .01 | $1,852 | 30-Apr-09 |
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Value shown is computed using the security's price on the report date given.
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