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Sunday, November 29, 2009, 1:21AM ET - U.S. Markets Closed. Dow  1.48% Nasdaq  1.73%

Orexigen Therapeutics, Inc. (OREX)

On Nov 27: 6.90   0.15 (2.13%)

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Major Holders Get Major Holders for:
BREAKDOWN % of Shares Held by All Insider and 5% Owners: 34% % of Shares Held by Institutional & Mutual Fund Owners: 53% % of Float Held by Institutional & Mutual Fund Owners: 81% Number of Institutions Holding Shares: 101 MAJOR DIRECT HOLDERS (FORMS 3 & 4) Holder Shares Reported BOCK LOUIS C N/A 27-Jul-09 SCHOEMAKER KATHLEEN K N/A 24-Nov-09 HALAK BRIAN K N/A 24-Nov-09 BLAIR JAMES C N/A 24-Nov-09 VITULLO NICOLE N/A 24-Nov-09
TOP INSTITUTIONAL HOLDERS Holder Shares % Out Value* Reported FEDERATED INVESTORS, INC. 2,682,436 5.70 $26,421,994 30-Sep-09 Barclays Global Investors UK Holdings Ltd 1,375,486 2.92 $13,548,537 30-Sep-09 WASATCH ADVISORS INC 1,053,700 2.24 $10,378,945 30-Sep-09 VANGUARD GROUP, INC. (THE) 942,641 2.00 $9,285,013 30-Sep-09 FMR LLC 6,865,036 14.59 $67,620,604 30-Sep-09 ADAGE CAPITAL PARTNERS GP, L.L.C. 838,901 1.78 $8,263,174 30-Sep-09 PRINCIPAL FINANCIAL GROUP, INC. 832,310 1.77 $8,198,253 30-Sep-09 LEUTHOLD WEEDEN CAPITAL MANAGEMENT, LLC 738,677 1.57 $7,275,968 30-Sep-09 FRANKLIN RESOURCES, INC 660,710 1.40 $6,507,993 30-Sep-09 MORGAN STANLEY 655,587 1.39 $6,457,531 30-Sep-09 TOP MUTUAL FUND HOLDERS Holder Shares % Out Value* Reported FEDERATED KAUFMANN FUND 2,459,000 5.23 $20,114,620 31-Jul-09 FIDELITY SELECT PORTFOLIOS - BIOTECHNOLOGY 1,243,748 2.64 $12,250,917 30-Sep-09 JENNISON SECTOR FDS-JENNISON HEALTH SCIENCES FD 801,700 1.70 $6,349,464 31-Aug-09 FIDELITY CONTRAFUND INC 574,700 1.22 $5,660,795 30-Sep-09 FRANKLIN STRATEGIC SERIES-FRANKLIN BIOTECHNOLOGY DISCOVE 524,154 1.11 $5,162,916 30-Sep-09 FIDELITY VALUE FUND 480,200 1.02 $4,729,970 30-Sep-09 LEUTHOLD CORE INVESTMENT FUND 432,810 .92 $4,263,178 30-Sep-09 ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND 410,557 .87 $2,652,198 31-Oct-09 ISHARES RUSSELL 2000 INDEX FD 391,113 .83 $3,852,463 30-Sep-09 WASATCH SMALL CAP GROWTH FUND 371,994 .79 $1,908,329 30-Jun-09 View Transactions for Insiders & Institutional Holders * Value shown is computed using the security's price on the report date given.
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