| TOP INSTITUTIONAL HOLDERS |
| Holder | Shares | % Out | Value* | Reported | | EASTBOURNE CAPITAL MANAGEMENT LLC | 3,230,204 | 7.65 | $16,344,832 | 30-Sep-09 | | Visium Asset Management | 2,671,749 | 6.33 | $13,519,049 | 30-Sep-09 | | Barclays Global Investors UK Holdings Ltd | 2,244,057 | 5.31 | $11,354,928 | 30-Sep-09 | | Park West Asset Management LLC | 1,897,294 | 4.49 | $9,600,307 | 30-Sep-09 | | RENAISSANCE TECHNOLOGIES, LLC | 1,706,647 | 4.04 | $8,635,633 | 30-Sep-09 | | BVF INC. | 1,667,000 | 3.95 | $8,435,020 | 30-Sep-09 | | VANGUARD GROUP, INC. (THE) | 1,558,760 | 3.69 | $7,887,325 | 30-Sep-09 | | DIMENSIONAL FUND ADVISORS LP | 1,051,980 | 2.49 | $5,323,018 | 30-Sep-09 | | Bank of New York Mellon Corporation | 939,614 | 2.23 | $4,754,446 | 30-Sep-09 | | STATE STREET CORPORATION | 759,209 | 1.80 | $3,841,597 | 30-Sep-09 |
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| Holder | Shares | % Out | Value* | Reported | | VANGUARD TOTAL STOCK MARKET INDEX FUND | 514,888 | 1.22 | $2,764,948 | 30-Jun-09 | | ISHARES RUSSELL 2000 INDEX FD | 512,326 | 1.21 | $2,592,369 | 30-Sep-09 | | EQ Advisors Trust-EQ/GAMCO Small Company Value Portfolio | 495,000 | 1.17 | $2,658,150 | 30-Jun-09 | | Advantage Funds, Inc.-Dreyfus Small Company Value Fund | 435,876 | 1.03 | $2,205,532 | 30-Sep-09 | | VANGUARD SMALL-CAP INDEX FUND | 435,772 | 1.03 | $2,340,095 | 30-Jun-09 | | DFA U.S. MICRO CAP SERIES | 410,909 | .97 | $1,947,708 | 30-Apr-09 | | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | 305,010 | .72 | $1,546,400 | 31-Oct-09 | | VANGUARD SMALL-CAP GROWTH INDEX FUND | 276,114 | .65 | $1,482,732 | 30-Jun-09 | | GABELLI SMALL CAP GROWTH FUND | 265,000 | .63 | $1,340,900 | 30-Sep-09 | | ISHARES RUSSELL 2000 GROWTH INDEX FD | 262,889 | .62 | $1,330,218 | 30-Sep-09 |
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Value shown is computed using the security's price on the report date given.
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