Karyopharm Therapeutics Inc. (KPTI)
Key Executives
Name | Title | Pay | Exercised | Year Born |
---|---|---|---|---|
Mr. Richard A. Paulson M.B.A. | President, CEO & Director | 1.43M | -- | 1967 |
Mr. Cameron Peters | Vice President of Finance, Assistant Treasurer & Principal Accounting Officer | -- | -- | 1960 |
Ms. Elhan Webb C.F.A. | Senior Vice President of Investor Relations | -- | -- | -- |
Dr. Amama Sadiq M.D., M.P.H. | Senior Vice President of Global Medical & Scientific Affairs | -- | -- | -- |
Karyopharm Therapeutics Inc.
- Sector:
- Healthcare
- Industry: Biotechnology
- Full Time Employees:
- 325
Description
Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma; in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma; and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). It also developing Selinexor for treating hematological and solid tumor malignancies, including multiple myeloma, endometrial cancer, myelofibrosis, and DLBCL; and ELTANEXOR for treating Myelodysplastic Neoplasms, as well as verdinexor, KPT-9274, and IL-12 compounds. The company has license agreement with Menarini Group to develop and commercialize selinexor for human oncology indications; license agreement with Antengene Therapeutics Limited to develop and commercialize selinexor, eltanexor, and KPT-9274 for the treatment and/or prevention of human oncology indications, as well as verdinexor for the diagnosis, treatment, and/or prevention of human non-oncology indications; and distribution agreement for the commercialization of XPOVIO with FORUS Therapeutics Inc. Further, it has a collaboration with Bristol Myers Squibb company to evaluate novel cereblon E3 ligase modulator agent mezigdomide in combination with Selinexor in patients with relapsed/refractory multiple myeloma. Karyopharm Therapeutics Inc. was incorporated in 2008 and is headquartered in Newton, Massachusetts.
Corporate Governance
Recent Events
- Apr 19, 2024DEFA14A: Proxy StatementsSee Full Filing
- Apr 08, 2024PRE 14A: Proxy StatementsSee Full Filing
- Feb 29, 202410-K: Periodic Financial ReportsSee Full Filing
- Feb 20, 20248-K: Corporate Changes & Voting MattersSee Full Filing
- Jan 25, 2024SC 13G/A: Tender Offer/Acquisition ReportsSee Full Filing