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Alnylam Pharmaceuticals, Inc. (ALNY)

146.07 +0.28 (+0.19%)
At close: April 23 at 4:00 PM EDT
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DELL
  • Previous Close 145.79
  • Open 147.35
  • Bid 145.76 x 100
  • Ask 146.16 x 200
  • Day's Range 145.61 - 150.27
  • 52 Week Range 143.50 - 218.88
  • Volume 532,485
  • Avg. Volume 851,193
  • Market Cap (intraday) 18.471B
  • Beta (5Y Monthly) 0.40
  • PE Ratio (TTM) --
  • EPS (TTM) -3.52
  • Earnings Date May 2, 2024
  • Forward Dividend & Yield --
  • Ex-Dividend Date --
  • 1y Target Est 222.41

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing, and commercializing novel therapeutics based on ribonucleic acid interference. Its marketed products include ONPATTRO (patisiran) for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; AMVUTTRA for the treatment of hATTR amyloidosis with polyneuropathy in adults; GIVLAARI for the treatment of adults with acute hepatic porphyria; and OXLUMO for the treatment of primary hyperoxaluria type 1. In addition, the company develops patisiran for the treatment of transthyretin amyloidosis, or ATTR amyloidosis, with cardiomyopathy; cemdisiran to treat complement-mediated diseases; Belcesiran for the treatment of alpha-1 liver disease; Elebsiran to treat chronic HBV infection; Zilebesiran to treat hypertension; ALN-APP to treat Alzheimer's disease and cerebral amyloid angiopathy; and ALN-HSD to treat NASH. Further, it offers Fitusiran for the treatment of hemophilia, Inclisiran to treat hypercholesterolemia, lumasiran for the treatment of advanced PH1, and vutrisiran for the treatment of ATTR amyloidosis, which is in phase 3 clinical trial. Alnylam Pharmaceuticals, Inc. has strategic collaborations with Regeneron Pharmaceuticals, Inc. to discover, develop, and commercialize RNAi therapeutics for a range of diseases by addressing therapeutic targets expressed in the eye and CNS; and Roche to develop pharmaceutical products containing zilebesiran. It also has license and collaboration agreements with Novartis AG; Vir Biotechnology, Inc.; Dicerna Pharmaceuticals, Inc.; Ionis Pharmaceuticals, Inc.; and PeptiDream, Inc. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts.

www.alnylam.com

2,100

Full Time Employees

December 31

Fiscal Year Ends

Recent News: ALNY

Performance Overview: ALNY

Trailing total returns as of 4/23/2024, which may include dividends or other distributions. Benchmark is

.

YTD Return

ALNY
23.69%
S&P 500
6.30%

1-Year Return

ALNY
30.20%
S&P 500
22.67%

3-Year Return

ALNY
6.02%
S&P 500
22.63%

5-Year Return

ALNY
75.65%
S&P 500
74.37%

Compare To: ALNY

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Statistics: ALNY

Valuation Measures

Annual
As of 4/23/2024
  • Market Cap

    18.47B

  • Enterprise Value

    17.34B

  • Trailing P/E

    --

  • Forward P/E

    --

  • PEG Ratio (5yr expected)

    --

  • Price/Sales (ttm)

    9.98

  • Price/Book (mrq)

    --

  • Enterprise Value/Revenue

    9.48

  • Enterprise Value/EBITDA

    -80.53

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    -24.08%

  • Return on Assets (ttm)

    -4.78%

  • Return on Equity (ttm)

    --

  • Revenue (ttm)

    1.83B

  • Net Income Avi to Common (ttm)

    -440.24M

  • Diluted EPS (ttm)

    -3.52

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    2.44B

  • Total Debt/Equity (mrq)

    --

  • Levered Free Cash Flow (ttm)

    146.53M

Research Analysis: ALNY

Analyst Price Targets

136.00
222.41 Average
146.07 Current
395.00 High
 

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell
 

Earnings

Consensus EPS
 

Company Insights: ALNY

Fair Value

146.07 Current
 

Dividend Score

0 Low
ALNY
Sector Avg.
100 High
 

Hiring Score

0 Low
ALNY
Sector Avg.
100 High
 

Insider Sentiment Score

0 Low
ALNY
Sector Avg.
100 High
 

Research Reports: ALNY

  • Morningstar | A Weekly Summary of Stock Ideas and Developments in the Companies We Cover

    In this edition, we explore the state of US auto market; margin of safety erased in US equity market rally; growing pains and growth in US equity market; and EOG Resources, Alnylam, and Pembina.

     
  • Analyst Report: Alnylam Pharmaceuticals, Inc.

    Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.

    Rating
    Price Target
     
  • Analyst Report: Alnylam Pharmaceuticals, Inc.

    Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.

    Rating
    Price Target
     
  • Analyst Report: Alnylam Pharmaceuticals, Inc.

    Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.

    Rating
    Price Target
     

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