U.S. markets open in 8 hours 6 minutes
  • S&P Futures

    4,271.25
    -9.75 (-0.23%)
     
  • Dow Futures

    33,649.00
    -69.00 (-0.20%)
     
  • Nasdaq Futures

    13,544.50
    -33.25 (-0.24%)
     
  • Russell 2000 Futures

    2,011.20
    -5.70 (-0.28%)
     
  • Crude Oil

    91.19
    -0.90 (-0.98%)
     
  • Gold

    1,809.30
    -6.20 (-0.34%)
     
  • Silver

    20.59
    -0.10 (-0.50%)
     
  • EUR/USD

    1.0250
    -0.0007 (-0.07%)
     
  • 10-Yr Bond

    2.8490
    0.0000 (0.00%)
     
  • Vix

    19.53
    -0.67 (-3.32%)
     
  • GBP/USD

    1.2116
    -0.0023 (-0.19%)
     
  • USD/JPY

    133.2560
    -0.2240 (-0.17%)
     
  • BTC-USD

    24,826.37
    +257.09 (+1.05%)
     
  • CMC Crypto 200

    592.07
    +20.79 (+3.64%)
     
  • FTSE 100

    7,500.89
    +34.98 (+0.47%)
     
  • Nikkei 225

    28,880.55
    +333.57 (+1.17%)
     

Anavex Life Sciences' Alzheimer's Candidate Mechanism Of Action Explained In Medical Journal

  • Oops!
    Something went wrong.
    Please try again later.
·1 min read
In this article:
  • Oops!
    Something went wrong.
    Please try again later.
  • Anavex Life Sciences Corp (NASDAQ: AVXL) has reported that ANAVEX 2-73 (blarcamesine) and ANAVEX3-71 (AF710B) are featured in a new peer-reviewed publication in the journal of Expert Opinion on Therapeutic Targets.

  • Scientific Paper Highlights:

    • Sigma-1 receptor (SIGMAR1)'s expression increases with age. However, in Alzheimer's disease (AD), it decreases and coincides with an age-related decrease in autophagy.

    • The SIGMAR1 may compensate for the loss of receptors and autophagic machinery during healthy aging.

    • ANAVEX-compounds activate SIGMAR1 and induce autophagy, a phenomenon that clears damaged cellular organelles and misfolded proteins.

    • Activation of the SIGMAR1 can induce cytoprotective autophagic pathways.

    • ANAVEX-compounds have also exhibited to block toxic Aβ, tau, and neuroinflammation.

  • Price Action: AVXL shares are up 20.7% at $18.71 during the market session on the last check Monday.

See more from Benzinga

© 2021 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.