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Anavex Life's Neurodegenerative Disease Candidate Meets Primary Endpoint In Early-Stage Study

Vandana Singh
·1 min read

Anavex Life Sciences Corp (NASDAQ: AVXL) announced topline results from its Phase 1 trial of ANAVEX3-71 in development for neurodegenerative diseases, including Frontotemporal Dementia (FTD).

  • ANAVEX3-71 was well tolerated in all cohorts receiving single doses of the treatment candidate ranging from 5 mg to 200 mg daily with no serious adverse events (SAEs) and no significant lab abnormalities in any subject.

  • In the study, ANAVEX3-71 exhibited linear pharmacokinetics. Its pharmacokinetics was also dose-proportional for doses up to 160 mg.

  • The study also met the secondary objective of characterizing the effect of ANAVEX 3-71 on electrocardiogram (ECG) parameters. There were no clinically significant ECG parameters throughout the study. Participant QTcF measures were normal across all dose groups with no difference between ANAVEX3-71 and Placebo.

  • Price Action: AVXL shares are up 0.06% at $15.54 during the premarket session on the last check Monday.

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