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ARCA Biopharma, European Patent for Gencaro and Q3 Review

NEW YORK, NY / ACCESSWIRE / November 20, 2017 / Traders News Source, a leading independent equity research and corporate access firm focused on small and mid-cap public companies is issuing a comprehensive report with no obligation on ARCA Biopharma, Inc. (ABIO), a biopharmaceutical company, focused on developing genetically-targeted therapies for cardiovascular diseases. Its lead product candidate is Gencaro, a pharmacologically beta-blocker and mild vasodilator, which is in clinical trial for the treatment of atrial fibrillation in chronic heart failure patients with reduced left ventricular ejection fraction.

The company's shares gained traction this week as the company announced the European patent, entitled "Methods and Compositions for Cardiovascular Diseases and Conditions," which provides protection for this novel approach to treating patients with cardiovascular disease and conditions. The European patent has been validated in ten countries: Denmark, France, Germany, Ireland, Italy, Netherlands, Spain, Sweden, Switzerland, and the United Kingdom.

Read details about the new Euro patent and review the Q3 financial results here READ MORE

Copy and paste to your browser may be required to view the report – http://tradersnewssource.com/arca-biopharma/

Beta-blockers, a well characterized class of drugs, target cardiac myocytes to reduce adverse beta1- adrenergic signaling that causes cardiac chamber remodeling. Gencaro's mechanism of action (MOA) is unique among beta-blockers due to its sympatholytic (norepinephrine lowering) and inverse agonism (inactivation of constitutively active receptors) properties.

ABIO has identified common genetic variations in receptors in the cardiovascular system they believe interact with Gencaro's pharmacology and may predict patient response to the drug. The genotype which responds most favorably to Gencaro, beta-1 389 arginine homozygous, is present in approximately 50% of the U.S. population.

Read more about Gencaro, and the clinical trials status in our report READ MORE

Copy and paste to your browser may be required to view the report – http://tradersnewssource.com/arca-biopharma/

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SOURCE: Traders News Source