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Blog Exposure - RXi Pharma and Iovance Biotherapeutics Announce Research Collaboration

LONDON, UK / ACCESSWIRE / May 15, 2018 / If you want access to our free research report on RXi Pharma Corp. (NASDAQ: RXII), all you need to do is sign up now by clicking the following link www.active-investors.com/registration-sg/?symbol=RXII as the Company's latest news hit the wire. On May 11, 2018, the Company announced that it has inked a research collaboration deal with Iovance Biotherapeutics, Inc. (NASDAQ: IOVA) ("Iovance") to evaluate the potential synergies with RXi's novel sd-rxRNA therapeutic compounds and Iovance's autologous cell therapy based on tumor-infiltrating lymphocytes (TILs), for use in the treatment of cancer. The financial terms of the transaction remained undisclosed. Register today and get access to over 1,000 Free Research Reports by joining our site below:


Active-Investors.com is focused on giving you timely information and the inside line on companies that matter to you. This morning, RXi Pharma and Iovance Biotherapeutics most recent news is on our radar and our team decided to put out a fantastic report on the company that is now available for free below:



RXi will Further Investigate and Expand Recently Published Data with TIL and Sd-rxRNA Products

Commenting on the announcement, Dr. Geert Cauwenbergh, President and Chief Executive Officer (CEO) of RXi, stated that the agreement will allow Iovance to explore their proprietary TIL technology and RXi's proprietary sd-rxRNA technology. Under this research collaboration, RXi will further investigate and expand the recently published data with TIL and sd-rxRNA products, which demonstrated the potentially enhanced tumor killing activity of TIL. Dr. Cauwenbergh added that as such, the Company may be able to improve the potency of the TIL product and also possibly broaden the applicability of TIL in other tumors types.

News reports suggest that post announcement of the news, RXi's shares surged in pre-market trade.

RXi and Gustave Roussy Research Collaboration

On November 13, 2017, RXi and Gustave Roussy, which is a leading Comprehensive Cancer Centre in Europe, entered into a collaborative research agreement to evaluate the potential of RXi's novel sd-rxRNA technology platform for use in cancer treatments. The agreement covered research to design and evaluate sd-rxRNA compounds in a human tumor xenograft model. Positive results might lead to further development of these compounds for the treatment of cancer. RXi's sd-rxRNA technology platform is broadly applicable to many therapeutic areas, including cancer.

RXI Announced Publication in Molecular Therapy on Sd-rxRNA® Targeting PD-1 in Adoptive Cell Therapy

On April 16, 2018, the Company announced that research conducted using its self-delivering RNAi platform in the field of immunotherapy to treat cancer was published in a leading peer-reviewed journal. The paper described research done to evaluate the potential of improving TIL therapy by applying RXi's novel sd-rxRNA compounds specific to PD-1. The results showed that targeting the PD-1/PD-L1 axis could enhance the ex-vivo expansion rate and in-vivo longevity of patient derived TILs used for ACT in malignant melanoma patients. Transfection of these T-cells with the PD-1 targeting self-delivering sd-rxRNA compounds was easy to incorporate in an established, clinically-relevant rapid expansion protocol, and resulted in increased functionality of the transfected TILs against autologous tumors compared to control TIL.

About Iovance Biotherapeutics, Inc.

Headquartered in San Carlos, California, Iovance Biotherapeutics is focused on the development and commercialization of autologous cellular immunotherapies optimizing personalized, tumor-directed TIL. Iovance is conducting three Phase-2 clinical trials to assess the efficacy and safety of autologous TIL for the treatment of patients with Metastatic Melanoma, Squamous Cell Carcinoma of the Head and Neck, and Cervical Cancer.

About RXi Pharmaceuticals Corp.

Founded in 2011 and headquartered in Marlborough, Massachusetts, RXi is a clinical-stage Company developing innovative therapeutics that address significant unmet medical needs. RXi developed a robust RNAi therapeutic platform, including sd-rxRNA® compounds, that have the ability to highly selectively block the expression of any target in the genome, thus providing applicability to a broad spectrum of therapeutic areas.

Stock Performance Snapshot

May 14, 2018 - At Monday's closing bell, RXi Pharma's stock rose 5.04%, ending the trading session at $2.50.

Volume traded for the day: 499.58 thousand shares, which was above the 3-month average volume of 391.28 thousand shares.

After yesterday's close, RXi Pharma's market cap was at $9.03 million.

The stock is part of the Healthcare sector, categorized under the Biotechnology industry. This sector was up 0.7% at the end of the session.


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