NEWARK, CA / ACCESSWIRE / April 25, 2016 / CymaBay Therapeutics Inc. (CBAY) a biopharmaceutical company focused on developing therapies to treat metabolic diseases, including serious rare and orphan disorders, recently provided corporate highlights and announced financial results for the quarter and year ended December 31, 2015. "We have made significant progress during the last quarter in advancing the development of our two key clinical assets," said Harold Van Wart, President and Chief Executive Officer of CymaBay. "Earlier in March, we reported some encouraging top-line data from our pilot Phase 2 study in patients with homozygous familial hypercholesterolemia. Analysis of the data showed that MBX-8025 demonstrated the ability to lower LDL-Cholesterol in a majority of patients, despite raising PCSK9 levels. We are evaluating the feasibility of conducting a second pilot study in combination with a PCSK9 inhibitor to assess whether the reductions in LDL-C can be amplified by neutralizing PCSK9."
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