Equillium Reveals Early Safety Data For Itolizumab In Lupus Patients

Vandana Singh
1 min read
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In this article:

  • Equillium Inc (NASDAQ: EQ) announced interim data from the Type A portion of the Phase 1b EQUALISE study in systemic lupus erythematosus (SLE) patients.

  • Data were presented at the American College of Rheumatology (ACR) annual meeting.

  • The data showed that itolizumab administration was well tolerated and decreased proteinuria and albuminuria, two key biomarkers of disease risk.

  • The data showed that for SLE patients with baseline urine protein-to-creatinine ratios (UPCR) over 100 mg/g (N=16) and 200 mg/g (N=6), UPCR 34% and 42% declined, respectively, at Day 57.

  • In addition, for patients with baseline urine albumin-to-creatinine ratio (UACR) of more than 30 mg/g (N=4), there was a decline of 54% at Day 57.

  • The Type B portion of the EQUALISE study will evaluate up to 20 newly diagnosed or refractory lupus nephritis patients who will be treated with itolizumab dosed at 1.6 mg/kg SC Q2W for up to 24 weeks.

  • Related Link: Equillium's Itolizumab Reduces Urine Protein In Lupus Patients.

  • Price Action: EQ shares are up 0.80% at $6.28 during the market session on the last check Tuesday.

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