After losing their unbeaten start to the season last Saturday against Manchester United, Leicester will once again try and assert themselves against an opposition who they see themselves as competing against for a top six position.
The Foxes will need to be defensively astute at home if they are to get anything from the game, but have not kept a clean sheet since their first match of the season.
Spurs will be looking to move on quickly from their Champions League opener, after they surrendered a two goal lead against Olympiacos.
Mauricio Pochettino said he was “very disappointed” with the result, and Harry Kane also admitted that the players made the same mistakes they have been making since Pochettino took over.
Here is everything you need to know ahead of the match.
When is it?
The game kicks off at 12.30pm on Saturday September 21.
How can I watch it?
BT Sport 1 will be showing the match, with coverage starting at 12pm.
BT subscribers can also live stream the match on PC, laptop or mobile using the BT Sport website or app.
Leicester – Schmeichel; Pereira, Evans, Soyuncu, Chilwell; Ndidi; Albrighton, Tielemans, Choudhury, Maddison; Vardy
Spurs – Lloris; Aurier, Alderweireld, Vertonghen, Rose; Winks, Sissoko, Eriksen, Alli, Kane, Son
Brendan Rodgers confirmed all his players are fit, including Ben Chilwell who missed a training session during the week.
Spurs will definitely be without Giovanni Lo Celso, and Ryan Sessengon and Juan Foyth also are unlikely to be involved.
Serge Aurier and Danny Rose are set to come back into the side after missing out midweek, and Mauricio Pochettino could return to a diamond in midfield.
Leicester have struggled defensively this season, and Spurs hit four last time out against Palace, so it seems likely that the away side will get chances.
The hosts have looked at their best when facing teams that play expansively, as Spurs tend to, so Jamie Vardy and James Maddison should have more joy than they did against United last weekend.
Leicester 1-2 Spurs.