TORONTO, ONTARIO--(Marketwire - Jan. 22, 2013) - Lorus Therapeutics Inc. (LOR.TO) ("Lorus"), a biopharmaceutical company specializing in the discovery, research and development of pharmaceutical products and technologies for the management of cancer, today announced that the United States Patent and Trademark Office has issued Lorus' patent for its novel cancer therapy IL-17E.
The US patent protects methods of treating cancer with IL-17E, both alone and in combination with anticancer therapy drugs including gemcitabine, paclitaxel, docetaxel, erlotinib, cisplatin, and bevacizumab. The patent covers the treatment of a wide range of cancers, including breast, lung, colon, pancreatic, gastric and ovarian tumors, as well as melanoma.
"The issuance of our US patent for IL-17E is another important step forward in the development of this innovative therapy," said Dr. Aiping Young, Lorus' President and CEO. "We and Cancer Research UK, our co-development partner, are committed to advancing IL-17E into clinical trials, and strong patent protection is part of our strategy to attain this goal."
IL-17E is a novel biological therapy based on human interleukin 17E, which is a cytokine protein that acts on cells of the immune system. IL-17E, which is in preclinical development in preparation for clinical trials, has potent anticancer properties against a range of solid tumors, including pancreatic, colon, lung, ovarian and breast cancers. IL-17E showed equivalent or superior efficacy as a single agent compared to marketed drugs used to treat these cancers, including Avastin, Tarceva, Taxotere, Taxol, Cisplatin, and Gemzar. IL-17E was also effective when used in combination with these drugs, and demonstrated antitumor efficacy that was greater than either agent alone without additional toxicity.
Lorus is a biopharmaceutical company focused on the discovery, research and development of novel therapeutics in cancer. Lorus' goal is to capitalize on its research, preclinical, clinical and regulatory expertise by developing new drug candidates that can be used, either alone, or in combination with other drugs, to successfully manage cancer. The Company also has expertise in antimicrobial drug discovery. Lorus Therapeutics Inc. is listed on the Toronto Stock Exchange under the symbol LOR.
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