NEW YORK (AP) — Stocks that moved substantially or traded heavily on Friday:
Flexion Therapeutics Inc., up $1.77 to $20.94
The FDA approved Flexion's application to update the label of its Zilretta osteoarthritis knee pain drug.
Michaels Cos., up $1.98 to $8.00
The arts and crafts chain tapped former Walmart executive Ashley Buchanan to be CEO.
Darden Restaurants Inc., down 90 cents to $108.01
Argus Research cut the chain restaurant owner from "Buy" to "Hold," citing softer customer traffic and rising costs.
RH (RH), down $12.87 to $214.87
The home decor retailer is being removed from the S&P SmallCap 600 and moved to the MidCap 400 next week.
Anixter International Inc., up $2.64 to $92.97
The supplier of communication and security products received a sweetened buyout offer from Wesco International.
General Mills Inc.., up 77 cents to $53.19
The consumer foods company benefited from an afternoon rally in household product companies.
American Airlines Group Inc., down $1.23 to $28.44
Airlines fell as a group and the Dallas-based carrier dropped the most.
Lincoln National Corp., down 77 cents to $58.74
Financial sector stocks fell as bond yields declined broadly.