U.S. markets open in 9 hours 30 minutes

Myriad Genetics' GUIDED Clinical Trial Outcome Encouraging

Zacks Equity Research

Myriad Genetics, Inc. MYGN announced the publication of a new analysis of the GUIDED clinical trial, using the 6-item Hamilton Depression Rating Scale (HAM-D6).

The primary finding was that the HAM-D6 scale identified statistically significant improvements across all three clinical endpoints — remission, response and symptoms – between GeneSight-guided care and treatment-as-usual at the end of the eighth week.

The result of this clinical trial is a major stride forward in the company’s commitment toward strengthening its portfolio of depressive disorder treatments.

More About the Study Results

The GUIDED study was the largest clinical prospective study evaluating the advantages of pharmacogenomics-guided treatment for depression using the GeneSight Psychotropic test over the use of an active therapy control arm.

As part of the GUIDED study protocol, all patients in the study had the 17-item HAM-D17 questionnaire administered. The 6-item HAM-D6 score represents a subset of HAM-D17 questions that have a more direct link to depression.

Clinical studies have shown that the HAM-D6 score is better equipped than HAM-D17 at distinguishing antidepressants from placebo. The scale has also proved to be a superior measure of core depressive symptoms than the HAM-D17 scale. This newly-published analysis also proves that the GeneSight test has resulted in significant and clinically relevant improvements in patients suffering from chronic depressive disorders compared to treatment-as-usual care.

Recent Developments

Lately, Myriad Genetics witnessed a crucial development pertainingtothe GeneSight Psychotropic test.

In November 2019, the company had announced the publication of a new analysis of the GUIDED clinical trial. The key finding was that the GeneSight Psychotropic test led to statistically significant improvement of clinical outcomes across all three endpoints — remission, response and symptoms — in patients taking medications with gene-drug interactions.

Price Performance

In the past three months, the company’s shares have underperformed the industry. The stock has lost 2.5% against the industry’s 22% growth.

Zacks Rank and Stocks Worth a Look

Myriad Genetics currently has a Zacks Rank #4 (Sell).

A few better-ranked stocks from the broader medical space are Haemonetics Corporation HAE, West Pharmaceutical Services WST and Omnicell OMCL. While Haemonetics sports a Zacks Rank #1 (Strong Buy), the other two carry a Zacks Rank #2 (Buy). You can see the complete list of today’s Zacks #1 Rank stocks here.

Haemonetics has a projected long-term earnings growth rate of 13.5%.

West Pharmaceutical Services has an expected long-term earnings growth rate of 14%.

Omnicell has a long-term earnings growth rate of 12.5%.

Just Released: Zacks’ 7 Best Stocks for Today

 Experts extracted 7 stocks from the list of 220 Zacks Rank #1 Strong Buys that has beaten the market more than 2X over with a stunning average gain of +24.6% per year.

These 7 were selected because of their superior potential for immediate breakout.

See these time-sensitive tickers now >>

Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report
Omnicell, Inc. (OMCL) : Free Stock Analysis Report
Haemonetics Corporation (HAE) : Free Stock Analysis Report
Myriad Genetics, Inc. (MYGN) : Free Stock Analysis Report
West Pharmaceutical Services, Inc. (WST) : Free Stock Analysis Report
To read this article on Zacks.com click here.
Zacks Investment Research