- Oops!Something went wrong.Please try again later.
Denmark-based Novo Nordisk A/S NVO announced that it has decided to initiate a phase IIIa study with oral semaglutide 50 mg in obesity. The decision comes after completion of the phase IIIa STEP study which evaluated once-weekly subcutaneous (sc) semaglutide 2.4 mg for the given indication.
The pivotal phase IIIa study is expected to begin in the second half of 2021. The study will evaluate the safety and efficacy of oral semaglutide versus placebo in approximately 1,000 people with obesity or overweight with comorbidities.
Please note that, Ozempic (semaglutide) 2.4 mg, a once-weekly glucagon-like peptide-1 (GLP-1) analog for weight management, is currently under review in the United States and in the EU as a treatment for adults with obesity. The regulatory filings were based on data from the phase IIIa STEP study which enrolled around 4,500 adults with overweight or obesity.
Shares of Novo Nordisk have rallied 6.3% so far this year compared with the industry’s increase of 3.2%.
We note that in December 2017, the FDA-approved Ozempic once-daily pre-filled pen to improve glycemic control in type II diabetes patients. In January 2020, the drug was approved in the United States for cardiovascular risk reduction in people with type II diabetes and established cardiovascular diseases.
Ozempic (0.5 mg and 1.0 mg doses) is currently approved in the United States and in the EU for the treatment of type II diabetes in adults.
We remind investors that oral semaglutide is marketed in the United Sates, the EU and in Japan under the brand name Rybelsus for treating type II diabetes as an adjunct to diet and exercise for adults with uncontrolled conditions.
Zacks Rank & Stocks to Consider
Novo Nordisk currently carries a Zacks Rank #3 (Hold). Better-ranked stocks in the healthcare sector include Bristol Myers Squibb Company BMY, Catalent, Inc. CTLT and Repligen Corporation RGEN, all carrying a Zacks Rank #2 (Buy) at present. You can see the complete list of today’s Zacks #1 Rank (Strong Buy) stocks here.
Bristol Myers’ earnings estimates have been revised 0.3% upward for 2021 and 0.8% upward for 2022 over the past 60 days. The stock has increased 6.9% year to date.
Catalent’s earnings estimates have been revised 1.8% upward for 2021 and 1.5% upward for 2022 over the past 60 days. The stock has inched up 6.9% year to date.
Repligen’s earnings estimates have been revised 15.1% upward for 2021 and 9.8% upward for 2022 over the past 60 days. The stock has rallied 13.6% year to date.
Bitcoin, Like the Internet Itself, Could Change Everything
Blockchain and cryptocurrency has sparked one of the most exciting discussion topics of a generation. Some call it the “Internet of Money” and predict it could change the way money works forever. If true, it could do to banks what Netflix did to Blockbuster and Amazon did to Sears. Experts agree we’re still in the early stages of this technology, and as it grows, it will create several investing opportunities.
Zacks’ has just revealed 3 companies that can help investors capitalize on the explosive profit potential of Bitcoin and the other cryptocurrencies with significantly less volatility than buying them directly.
See 3 crypto-related stocks now >>
Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report
Novo Nordisk AS (NVO) : Free Stock Analysis Report
Bristol Myers Squibb Company (BMY) : Free Stock Analysis Report
Repligen Corporation (RGEN) : Free Stock Analysis Report
Catalent, Inc. (CTLT) : Free Stock Analysis Report
To read this article on Zacks.com click here.