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Novocure's Cancer Treating Electric Fields Improves Survival In Lung Cancer Patients, But Stock Tumbles On Remaining Doubts

  • Zai Lab Limited (NASDAQ: ZLAB) and Novocure Limited (NASDAQ: NVCR) presented results from the phase 3 LUNAR trial evaluating the use of Tumor Treating Fields (TTFields) therapy together with standard therapies for non-small cell lung cancer (NSCLC) at the 2023 American Society of Clinical Oncology Annual Meeting.

  • The LUNAR trial met its primary endpoint with a statistically significant and clinically meaningful 3-month improvement in median overall survival (OS) when TTFields therapy was added to standard therapies.

  • Patients randomized to receive TTFields therapy and standard therapies demonstrated a median OS of 13.2 months compared to 9.9 months in patients treated with standard therapies alone.

  • Also Read: Novocure Stock Surges As Tumor Treating Fields Shows Overall Survival In Lung Cancer Patients.

  • Patients randomized to receive TTFields therapy and physician's choice immune checkpoint inhibitor demonstrated a median OS of 18.5 months versus a median OS of 10.8 months in patients treated with ICIs alone.

  • Patients randomized to receive TTFields therapy and docetaxel had a positive survival trend with a median OS of 11.1 months vs. 8.7 months in patients treated with docetaxel alone.

  • Median progression-free survival (PFS) for patients treated with TTFields therapy and standard therapies was 4.8 months versus 4.1 months in patients treated with standard therapies alone.

  • Stat News noted that the data does not fit the current medical practice for lung cancer patients as 70% of the study participants did not receive initial immune checkpoint inhibitor treatment, such as Merck & Co Inc's (NYSE: MRK) Keytruda, which dominates current therapy.

  • Price Action: NVCR shares are down 26.3% at $60.78 on the last check Tuesday.

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This article Novocure's Cancer Treating Electric Fields Improves Survival In Lung Cancer Patients, But Stock Tumbles On Remaining Doubts originally appeared on Benzinga.com

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