Julien Perrier brings extensive immunotherapy business operation experience
- To prepare the best commercial alliance for Phase 3 NSCLC candidate Tedopi®
- To strengthen commitment to clinical FR104 CD28 antagonist autoimmune program
- To establish U.S.-based global strategic development and operational team in Boston
NANTES, France, Dec. 17, 2018 (GLOBE NEWSWIRE) -- OSE Immunotherapeutics SA (ISIN: FR0012127173; Mnémo: OSE) today announced the appointment of Julien Perrier as chief commercial officer. Mr. Perrier has an extensive background in marketing and commercialization of leading immunotherapy products and will be the founding member of the Company’s new Boston-based, U.S. global development team specialized in immunotherapy.
“By the end of 2019 we are looking forward to providing the first results from our pivotal Phase 3 trial of Tedopi® to treat non-small cell lung cancer for patients who have failed checkpoint inhibitor treatment, the current standard of care for this cancer indication. Julien's experience in business operations and commercial alliances will allow us to accelerate our efforts to position Tedopi® as an important new therapeutic option for patients suffering from this devastating disease,” said Alexis Peyroles, chief executive officer of OSE Immunotherapeutics. “Julien’s experience in immunology and biologics will also prove essential as we plan next steps for FR104, a Phase 2-ready, first-in-class CD28 antagonist with exciting potential to treat autoimmune disease and an important value driver for OSE moving forward.”
Most recently, Mr. Perrier was head of the immunology division, France, at AbbVie, where he oversaw the commercial operations for Humira® as well as preparations for the launch of two additional immunology products. From 2013 to 2017, Mr. Perrier was head of operations and portfolio management at the biological products division of Sanofi in partnership with Regeneron, specializing in immunology. From 2004 to 2013, much of that time based in the U.S., he held multiple positions for Sanofi, including serving as director of strategy and operations and acting vice president commercial operations for Dupixent®, a monoclonal antibody targeting three indications.
Julien Perrier said, “I am excited to bring my expertise in global business and immunology to the team at OSE Immunotherapeutics, a highly validated leader in the development of exciting novel therapeutic-candidates for the modulation of immune responses to treat both cancer and autoimmune disease. I look forward to contributing to OSE’s strategy as its assets progress through clinical development and into commercialization.”
ABOUT OSE Immunotherapeutics
OSE Immunotherapeutics is a clinical-stage biotechnology company focused on developing and partnering therapies to control the immune system for immuno-oncology and autoimmune diseases. The company has a diversified first-in-class clinical portfolio consisting of several scientific and technological platforms including neoepitopes and agonist or antagonist monoclonal antibodies, all ideally positioned to fight cancer and autoimmune diseases. The
most advanced therapeutic-candidate, Tedopi®, is a proprietary combination of 10 neo-epitopes aimed at stimulating T-lymphocytes and is currently in Phase 3 development in non-small cell lung cancer (NSCLC) after checkpoint inhibitor failure (anti PD-1 and anti PD-L1) and in Phase 2 testing in pancreatic cancer in combination with checkpoint inhibitor Opdivo. FR104 (an anti-CD28 mAb) has successfully completed Phase 1 testing and has potential to treat autoimmune diseases. In April 2018, Boehringer Ingelheim and OSE signed a global license and collaboration agreement to develop preclinical checkpoint inhibitor OSE-172 (anti-SIRPa monoclonal antibody) in multiple cancer indications. OSE-127 (monoclonal antibody targeting the CD127 receptor, the alpha chain of the interleukin-7 receptor) is partnered with Servier Laboratories under an option agreement up to the completion of a planned Phase 2 clinical trial planned in autoimmune bowel disease and Sjogren’s syndrome. In November 2018, OSE received CTA approval to initiate a Phase 1 clinical trial of OSE-127.
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