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Payor Re-Evaluation On Exondys Positive For Sarepta

Manikandan Raman

Cowen sees positive trends over payor evaluation and re-evaluation of Sarepta Therapeutics Inc (NASDAQ: SRPT)’s Exondys 51, which was approved in last September for the treatment Duchenne Muscular Dystrophy.

Encouraging Trends

Analyst Ritu Baral noted that checks show that payor discussions are continuing regarding Exondys 51 with manageable, increasingly positive feedback. The analyst pointed out that, despite initial denial of coverage, it appears that Anthem has re-evaluated its decision on Exondys.

Based on Anthem’s February Specialty Pharmacy Medical Management Prior Authorization Drug List, it appears Anthem will add Exondys 51 to its prior authoration list as of May 1.

“We think this is encouraging and indicative of the evolving payor landscape surrounding Exondys 51 and more broadly, DMD,” Baral wrote in a note.

“Anthem's pick-up, together with those such as UnitedHealth Group Inc (NYSE: UNH), which started coverage on Feb. 1, support the idea of accelerating new patient starts, suggested by SRPT last week at our Healthcare Conference,” Baral continued.

Denials Persist, But Unlikely To be Permanent

That said, Baral added that coverage discussions appear to be ongoing and amenable patients are still experiencing denials.

However, the analyst highlighted that many key opinion leaders (KOLs) believe that the benefit of the drug may extend well past loss of ambulation, potentially improving respiratory and upper limb strength as well as functional activities of daily living.

At last check, shares of Sarepta fell 2.66 percent to $31.86. Baral has an Outperform rating on the stock, with a price target of $62.


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  • Latest Ratings for SRPT

    Date Firm Action From To
    Mar 2017 Leerink Swann Upgrades Market Perform Outperform
    Mar 2017 Nomura Initiates Coverage On Buy
    Dec 2016 JP Morgan Initiates Coverage On Overweight

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