Italy begin their Rugby World Cup campaign in the early hours of Sunday morning when they take on international minnows Namibia.
Italy simply have to win if they are to stand any chance of upsetting the odds and reaching the knockout stages of the tournament, having been drawn in the same pool as both New Zealand and South Africa.
Their opening fixture will also be captain Sergio Parisse's 141st appearance for Italy, leaving him just seven behind former New Zealand captain Richie McCaw's world record of 148 international caps.
Namibia, ranked one place below Canada at 23rd in the world, have lost all 19 of their World Cup matches to date and have been on the receiving end of some of the tournament's biggest thrashings.
Here is what you need to know ahead of the fixture.
When is the match?
The match is on Sunday 22 September.
What time is kick-off?
Kick-off is at 06.15am GMT.
Where can I watch it?
The match will be shown live on ITV One.
It will also be available to stream online at the ITV Hub.
What are the teams?
Italy: 15. Jayden Hayward, 14. Mattia Bellini, 13. Tommaso Benvenuti, 12. Luca Morisi, 11. Edoardo Padovani, 10. Tommaso Allan, 9. Tito Tebaldi, 1. Nicola Quaglio, 2. Luca Bigi, 3. Tiziano Pasquali, 4. Alessandro Zanni, 5. Federico Ruzza, 6. Braam Steyn, 7. Maxime Mbanda, 8. Sergio Parisse (c)
Replacements: 16. Oliviero Fabiani, 17. Simone Ferrari, 18. Marco Riccioni, 19. Dean Budd, 20. Jake Polledri, 21. Guglielmo Palazzani, 22. Carlo Canna, 23. Matteo Minozzi
Namibia: 15. Johan Tromp, 14. Chad Pato, 13. Justin Newman, 12. Darryl De La Harpe, 11. JC Greyling, 10. Cliven Loubser, 9. Damian Stevens, 1. Andre Rademeyer, 2. Torsten George van Jaarsveld, 3. Johannes Coetzee, 4. PJ Van Lill, 5. Tijuee Uanivi (c), 6. Rohan Kitshoff, 7. WIan Conrade, 8. Janco Venter
Replacements: 16. Louis van der Westhuizen, 17. AJ De Klerk, 18. Nelius Theron, 19. Johan Retief, 20. Max Katjijeko, 21. Eugene Jantjies, 22. Helarius Axasman Kisting, 23. Lesley Klim
What are the odds?
Italy to win: 1/50
Namibia to win: 20/1