The New England Patriots and Seattle Seahawks were among the most impressive teams in Week 1 - now they meet at CenturyLink Field on Sunday Night Football.
Cam Newton, Tom Brady's replacement at quarterback, led New England to a 21-11 victory over the Miami Dolphins, while Russell Wilson put on a passing clinic when completing 31 of his 35 attempts in Seattle's 38-25 win over the Atlanta Falcons.
A repeat of Super Bowl XLIX is the standout game of Sunday's slate, though there are plenty more mouth-watering encounters, including the Baltimore Ravens facing the Houston Texans.
Here we break down the big matchups using Stats Perform data.
Patriots at Seahawks - Sunday, 8.20pm (all times Eastern)
- This will be the first game in NFL history in which both teams will have a head coach aged 68 or older. Seahawks coach Pete Carroll is 69, while Patriots coach Bill Belichick is 68.
- Newton led the Patriots with 75 yards rushing on a game-high 15 carries in his Pats debut last week. Should he finish as New England's leading rusher again in Seattle, Newton will be his team's leading rusher for a 37th time - a new record for the most such games by a quarterback in the Super Bowl era (since 1966).
- New England have won eight straight games against NFC opponents, including their Super Bowl LIII win over the Los Angeles Rams, dating back to a loss to the Detroit Lions in Week 3 of the 2018 season.
OTHER KEY GAMES
Rams at Eagles - Sunday, 1pm
- The Eagles have won the last six meetings between these teams, including one-score wins in Los Angeles in 2017 (43-35) and 2018 (30-23). They have averaged 32.2 points during the win streak, with at least 30 points in each of the last five meetings.
Broncos at Steelers - Sunday, 1pm
- The Broncos have won four of the last five games against the Steelers, including two playoff wins. Four of those five games were decided by seven points or fewer.
Chiefs at Chargers - Sunday, 4.25pm
- After starting last season 6-4, Kansas City have won 10 straight games - regular season and playoffs. The streak began last November with a win over the Chargers in Mexico City. Each of the last seven victories have come by a double-digit margin; since 2000, only the 2007 Patriots (eight games) have had a longer streak of wins by 10 or more points.
Ravens at Texans - Sunday, 4.25pm
- The Ravens have gone 12 straight regular-season games without trailing in the second half, the longest streak by any NFL team since the Chicago Bears had a 12-game streak from 1933-34. The last team to have a streak longer than 12 games was the Green Bay Packers from 1929-30 (18).
Saints at Raiders - Monday, 4.15pm
- Josh Jacobs had three rushing touchdowns in Week 1, becoming the first Raider to do so since Latavius Murray, who is now with New Orleans, had three in Week 9 of 2016. Only two Raiders have rushed for three touchdowns more than once – Marcus Allen (five times) and Pete Banaszak (twice).
Falcons at Cowboys - Sunday, 1pm
- Dak Prescott has not been intercepted in his last 223 pass attempts going back to last November, the longest streak in Cowboys history. Troy Aikman held the previous mark at 216 passes in 1999.
Lions at Packers - Sunday, 1pm
- Green Bay have won seven straight home openers since a 30-22 loss against the San Francisco 49ers in 2012. That is the second-longest active streak of its kind, behind the Seahawks (11 straight).