There's 'Outsized' Risk-Reward For This Biotech, Morgan Stanley Says, Predicting Shares Could Grow More Than 30%

In this article:
  • Morgan Stanley has assumed coverage on Ionis Pharmaceuticals Inc (NASDAQ: IONS) with an Overweight (previously Underweight) rating and a price target of $57 from $30 to capture the optionality in these near-term readouts.

  • The analyst has added estimates for Ionis's near-term pipeline products (donidalorsen, fesomersen, IONIS-AGT-LRx, IONIS-FBLRx, and cimdelirsen) as well as associated increases in operating expenses to fund these programs.

  • Related: AstraZeneca - Ionis Eplontersen Achieves Positive Data In Rare Disease Trial.

  • The shift is due to increased confidence in the pipeline and ascribing more credit to the mid-to-late stage assets, as the antisense platform may finally be ready for "prime time" given chemistry modifications, s improved tissue targeting, and reduced risk of adverse events.

  • "Given the significant portion of valuation tied up in cash and Spinraza royalties, we see outsized risk-reward heading into several near-term catalysts over the next 12-18 months," the analyst writes.

  • Price Action: IONS shares are up 6.74% at $47.26 on the last check Friday.

Latest Ratings for IONS

Date

Firm

Action

From

To

Mar 2022

Guggenheim

Initiates Coverage On

Buy

Mar 2022

Citigroup

Initiates Coverage On

Sell

Feb 2022

SVB Leerink

Maintains

Market Perform

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