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UNITY Biotechnology, Inc. Reports Fourth Quarter and Full Year 2019 Financial Results

SOUTH SAN FRANCISCO, Calif., March 11, 2020 (GLOBE NEWSWIRE) -- UNITY Biotechnology, Inc. (UNITY) [NASDAQ:UBX], a biotechnology company developing therapeutics to extend healthspan by slowing, halting or reversing diseases of aging, today reported financial results for the fourth quarter and full year ended December 31, 2019. Unity issued a press release providing pipeline and business updates on February 25, 2020.

Fourth Quarter and Full Year 2019 Financial Results

Cash, cash equivalents and investments totaled $125.0 million as of December 31, 2019 compared with $171.1 million as of December 31, 2018.

Operating loss for the twelve months ended December 31, 2019 was $89.7 million compared to $79.5 million for the twelve months ended December 31, 2018. Cash used in operations during the year ended 2019 was $72.4 million compared to $56.6 million for the year ended 2018. Total operating loss for the three months ended December 31, 2019 was $23.1 million compared to $22.8 million for the fourth quarter of 2018. Cash used in operations during the fourth quarter of 2019 was $15.7 million compared to $12.8 million for the fourth quarter of 2018.

Research and development expenses were $71.0 million for the year ended December 31, 2019 compared to $58.9 million for the year ended December 31, 2018. The increase of $12.1 million was primarily due to a net increase of $2.3 million for personnel-related expenses, which was partially offset by a decrease of $1.1 million related to non-cash stock compensation expense, $6.7 million for outside research and development activities and $3.1 million in lab and facilities-related costs. Research and development expenses were $18.2 million for the three months ended December 31, 2019 compared to $16.3 million for the three months ended December 31, 2018. The increase of $1.9 million was primarily due to $0.5 million for personnel-related expenses and $1.1 million for outside research and development activities.

General and administrative expenses were $20.0 million for the year ended December 31, 2019 compared to $16.0 million for the year ended December 31, 2018. The increase of $4.0 million was primarily due to an increase of $3.4 million for personnel-related expenses, of which $2.5 million was related to non-cash stock compensation expense, and $0.6 million in insurance-related expenses, partially offset by $0.5 million decrease in professional fees. General and administrative expenses were $4.9 million for the three months ended December 31, 2019 compared to $4.3 million for the three months ended December 31, 2018. The $0.6 million increase was primarily due to personnel-related costs, primarily attributable to non-cash stock-based compensation expense.

About UNITY
UNITY is developing therapeutics to extend healthspan with an initial focus on cellular senescence. UNITY believes that the accumulation of senescent cells is a fundamental mechanism of aging and a driver of many common age-related diseases. Cellular senescence is a natural biological state in which a cell permanently halts division. As senescent cells accumulate with age, they begin secreting inflammatory factors, proteases, fibrotic factors, and growth factors, that disturb the tissue micro-environment. This collection of secreted proteins is referred to as the Senescence Associated Secretory Phenotype, or SASP. UNITY is developing senolytic medicines to eliminate senescent cells and thereby stop the production of the SASP, which UNITY believes addresses a root cause of age-related diseases. By stopping the production of the SASP at it source, UNITY believes senolytic medicines could slow, halt, or reverse diseases such as osteoarthritis and age-related eye diseases. More information is available at www.unitybiotechnology.com or follow us on Twitter.

Forward-Looking Statements
This press release contains forward-looking statements including statements related to the potential for UNITY to develop therapeutics to extend healthspan. These statements involve substantial known and unknown risks, uncertainties and other factors that may cause our actual results, levels of activity, performance or achievements to be materially different from the information expressed or implied by these forward-looking statements. We may not actually achieve the plans, intentions or expectations disclosed in our forward-looking statements, and you should not place undue reliance on our forward-looking statements. Actual results or events could differ materially from the plans, intentions and expectations disclosed in the forward-looking statements we make. The forward-looking statements in this press release represent our views as of the date of this release. We anticipate that subsequent events and developments will cause our views to change. However, while we may elect to update these forward-looking statements at some point in the future, we have no current intention of doing so except to the extent required by applicable law. You should, therefore, not rely on these forward-looking statements as representing our views as of any date subsequent to the date of this release. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to the business of the Company in general, see UNITY’s most recently filed Quarterly Report on Form 10-Q for the quarter ended September 30, 2019, filed with the Securities and Exchange Commission on November 6, 2019, as well as other documents that may be filed by UNITY from time to time with the Securities and Exchange Commission.

Unity Biotechnology, Inc.
Condensed Statements of Operations and Comprehensive Loss
(In thousands, except share and per share amounts)
 
    Three Months Ended     Year Ended  
    December 31,     December 31,  
    2019     2018     2019     2018  
Operating expenses:                                
Research and development   $ 18,207     $ 16,331     $ 70,957     $ 58,907  
General and administrative     4,907       4,328       20,046       16,016  
Change in fair value of contingent consideration     (24 )     2,149       (1,352 )     4,542  
Total operating expenses     23,090       22,808       89,651       79,465  
Loss from operations     (23,090 )     (22,808 )     (89,651 )     (79,465 )
Interest income, net     627       1,066       3,289       3,312  
Other income (expense), net     4,436       (175 )     4,185       (245 )
Net loss     (18,027 )     (21,917 )     (82,177 )     (76,398 )
Other comprehensive loss                                
Unrealized gain (loss) on marketable securities, net of tax     (5 )     24       185       9  
Comprehensive loss   $ (18,032 )   $ (21,893 )   $ (81,992 )   $ (76,389 )
Net loss per share, basic and diluted   $ (0.39 )   $ (0.53 )   $ (1.88 )   $ (2.70 )
Weighted-average number of shares used in
  computing net loss per share, basic and
  diluted
    45,975,828       41,221,223       43,624,807       28,269,907  
                                 


Unity Biotechnology, Inc.
Condensed Balance Sheets
(In thousands)
 
    December 31,     December 31,  
    2019     2018  
Assets                
Current Assets:                
Cash and cash equivalents   $ 37,473     $ 15,399  
Short-term marketable securities     84,508       155,736  
Strategic investments     5,507        
Prepaid expenses and other current assets     1,999       1,830  
Total current assets     129,487       172,965  
Property and equipment, net     16,636       6,238  
Long-term marketable securities     3,025        
Restricted cash     1,446       550  
Other long-term assets     627       1,622  
Total assets   $ 151,221     $ 181,375  
                 
Liabilities, convertible preferred stock, and
  stockholders' equity
               
Current liabilities:                
Accounts payable   $ 5,185     $ 4,847  
Accrued compensation     5,905       3,791  
Accrued and other current liabilities     4,995       4,990  
Settlement liability           2,059  
Contingent consideration liability     1,131       895  
Total current liabilities     17,216       16,582  
Deferred rent, net of current portion     13,298       2,467  
Contingent consideration liability, net of current portion           1,588  
Other non-current liabilities           45  
Total liabilities     30,514       20,682  
                 
Stockholders' equity:                
Common stock     5       4  
Additional paid-in capital     366,695       324,663  
Related party promissory notes for purchase
  of common stock
    (210 )     (201 )
Employee promissory notes for purchase
  of common stock
    (418 )     (400 )
Accumulated other comprehensive loss     90       (95 )
Accumulated deficit     (245,455 )     (163,278 )
Total stockholders' equity     120,707       160,693  
Total liabilities, convertible preferred stock, and
  stockholders' equity
  $ 151,221     $ 181,375  
                 


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