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Wired News – Anavex Life Sciences To Commence Phase-2 Study of ANAVEX(R)2-73 in Parkinson’s Disease Dementia

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LONDON, UK / ACCESSWIRE / April 19, 2018 / Active-Investors.com has just released a free research report on Anavex Life Sciences Corp. (NASDAQ: AVXL) ("Anavex"). If you want access to this report all you need to do is sign up now by clicking the following link www.active-investors.com/registration-sg/?symbol=AVXL as the Company's latest news hit the wire. On April 17, 2018, the Company, which is a publicly-traded biopharmaceutical organization dedicated to the development of differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental diseases, announced its plans of initiating the Phase-2 clinical trial for its lead candidate ANAVEX®2-73 in Parkinson's Disease Dementia (PDD). Register today and get access to over 1000 Free Research Reports by joining our site below:


Active-Investors.com is currently working on the research report for Aeterna Zentaris Inc. (NASDAQ: AEZS), which also belongs to the Healthcare sector as the Company Anavex Life Sciences. Do not miss out and become a member today for free to access this upcoming report at:


Active-Investors.com is focused on giving you timely information and the inside line on companies that matter to you. This morning, Anavex Life Sciences most recent news is on our radar and our team decided to put out a fantastic report on the company that is now available for free below:


PDD, A Debilitating Condition

Parkinson's Disease is a common neurological disorder observed in older adults. On average, this disease affects 2% of people aged 65 years and above. According to the Parkinson's Foundation, Parkinson's Disease affects approximately 1 million Americans. About 50% to 80% of people living with Parkinson's Disease eventually experience PDD. Parkinson's Disease causes brain changes in a certain region that plays an important role in movement. As the disease spreads, it begins to hamper mental functions such as memory, and the ability to pay attention and make sound judgments. However, currently there are no adequate treatment options for this condition.

About ANAVEX®2-73

Anavex's lead drug candidate, ANAVEX®2-73, is an oral available drug that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors. Anavex's pre-clinical studies validate its potential to reverse the course of Alzheimer's Disease. The drug also demonstrated anticonvulsant, anti-amnesic, neuroprotective, and anti-depressant properties in animal models, which highlight its potential to treat additional central nervous system (CNS) disorders, such as epilepsy.

On August 12, 2015, the Michael J. Fox Foundation for Parkinson's Research awarded Anavex a research grant to develop ANAVEX®2-73 for the treatment of Parkinson's Disease. The grant fully funded the pre-clinical study for moving ANAVEX®2-73 into a Parkinson's Disease clinical trial.

Phase-2 Trial with ANAVEX®2-73 in PDD

There is a significant unmet medical need for the treatment of people suffering with PDD. Thus, Anavex intends to commence the double-blind, randomized, placebo-controlled Phase-2 trial to evaluate the efficacy of ANAVEX®2-73 on the cognitive and motor impairment of PDD. The study has been submitted for approval to regulatory authorities in Europe. Post the approval, Anavex plans to initiate this clinical trial in the second half of 2018.

Christopher U Missling, PhD, President and Chief Executive Officer (CEO) at Anavex, expressed his excitement on commencing the Phase-2 Trial of ANAVEX®2-73 for patients suffering with PDD. He affirmed that the Company would remain focused on the discovery and development of potential treatments for neurological diseases with unmet needs, such as Alzheimer's Disease and Rett Syndrome.

Phase-2 Study of ANAVEX®2-73 for Rett Syndrome

Additionally, Anavex submitted an updated investigational new drug (IND) application to the US Food and Drug Administration (FDA) for the double blind, randomized, placebo-controlled ANAVEX®2-73 Phase-2 Study in Rett Syndrome during the first quarter of 2018. At present, the Company is working with the agency on this submission and expects initiation of the clinical trial in the second half of 2018.

Stock Performance Snapshot

April 18, 2018 - At Wednesday's closing bell, Anavex Life Sciences' stock rose 3.83%, ending the trading session at $2.17.

Volume traded for the day: 266.75 thousand shares.

After yesterday's close, Anavex Life Sciences' market cap was at $99.02 million.

The stock is part of the Healthcare sector, categorized under the Biotechnology industry. This sector was flat at the end of the session.


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