U.S. markets open in 1 hour 4 minutes
  • S&P Futures

    3,824.25
    -3.75 (-0.10%)
     
  • Dow Futures

    31,241.00
    -130.00 (-0.41%)
     
  • Nasdaq Futures

    12,849.00
    +17.25 (+0.13%)
     
  • Russell 2000 Futures

    2,190.20
    -9.80 (-0.45%)
     
  • Crude Oil

    62.14
    -1.39 (-2.19%)
     
  • Gold

    1,762.80
    -12.60 (-0.71%)
     
  • Silver

    26.86
    -0.82 (-2.96%)
     
  • EUR/USD

    1.2118
    -0.0068 (-0.56%)
     
  • 10-Yr Bond

    1.5180
    0.0000 (0.00%)
     
  • Vix

    29.46
    +8.12 (+38.05%)
     
  • GBP/USD

    1.3917
    -0.0095 (-0.68%)
     
  • USD/JPY

    106.3250
    +0.0950 (+0.09%)
     
  • BTC-USD

    46,450.45
    -3,913.02 (-7.77%)
     
  • CMC Crypto 200

    927.30
    -5.84 (-0.63%)
     
  • FTSE 100

    6,528.39
    -123.57 (-1.86%)
     
  • Nikkei 225

    28,966.01
    -1,202.26 (-3.99%)
     

The Zacks Analyst Blog Highlights: Intellia Therapeutics, Editas Medicine, Fate Therapeutic, CRISPR Therapeutics and Vertex Pharmaceuticals

  • Oops!
    Something went wrong.
    Please try again later.
  • Oops!
    Something went wrong.
    Please try again later.
  • Oops!
    Something went wrong.
    Please try again later.
  • Oops!
    Something went wrong.
    Please try again later.
  • Oops!
    Something went wrong.
    Please try again later.
Zacks Equity Research
·5 min read
  • Oops!
    Something went wrong.
    Please try again later.
  • Oops!
    Something went wrong.
    Please try again later.
  • Oops!
    Something went wrong.
    Please try again later.
  • Oops!
    Something went wrong.
    Please try again later.
  • Oops!
    Something went wrong.
    Please try again later.

For Immediate Release

Chicago, IL – January 11, 2021 – Zacks.com announces the list of stocks featured in the Analyst Blog. Every day the Zacks Equity Research analysts discuss the latest news and events impacting stocks and the financial markets. Stocks recently featured in the blog include: Intellia Therapeutics, Inc. NTLA, Editas Medicine, Inc. EDIT, Fate Therapeutic, Inc. FATE, CRISPR Therapeutics AG CRSP and Vertex Pharmaceuticals Incorporated VRTX.

Here are highlights from Friday’s Analyst Blog:

CRISPR Gets Gene-Editing Stocks Up on Intellia's Pipeline Update

Intellia Therapeutics provided an update on its pipeline plans for 2021 wherein it said it will file investigational new drug applications (IND) to begin clinical studies on its two CRISPR-based candidates, NTLA-5001 and NTLA-2002 this year. While an IND or IND-equivalent for NTLA-5001 for the treatment of acute myeloid leukemia (AML) will be filed by mid-year, the same for NTLA-2002 for the treatment of hereditary angioedema (HAE), a swelling disorder, is expected to be filed in the second half. The INDs, if approved, will allow Intellia to begin clinical studies on the candidates.

CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats. The technology can selectively delete, modify or correct a disease-causing abnormality in a specific deoxyribonucleic acid segment.

Meanwhile, Intellia Therapeutics' lead pipeline candidate is NTLA-2001, a potentially curative single-course therapy to treat transthyretin amyloidosis ("ATTR"), a rare inherited disease. In November, Intellia dosed the first patient in a phase I study on NTLA-2001 in hereditary ATTR with polyneuropathy (hATTR-PN), which marked the company's transition to a clinical stage biotech. Intellia has plans to study NTLA-2001 in a broader ATTR population of both polyneuropathy and cardiomyopathy patients.

In the latest press release, Intellia also announced plans to nominate at least one additional development candidate in 2021.

Shares of Intellia were up 16.1% on Thursday as the update on its gene-editing drugs excited investors. Moreover, the news pushed up stocks of other companies, Editas Medicine Fate Therapeutics and CRISPR Therapeutics, which make gene-editing drugs using the CRISPR technology.  Shares of CRISPR Therapeutics, Fate Therapeutics and Editas jumped a respective 18.7%, 17.5% and 11.3%

Genomic editing to repair a defective genetic material that causes diseases using CRISPR technology is probably one of the most promising and exciting healthcare innovations seen in decades. The technology has the potential to change how diseases, especially those caused by genetic mutations, are treated.

Editas' lead pipeline candidate is EDIT-101, which employs CRISPR gene editing to treat LCA10 — a rare genetic illness that causes blindness. Editas completed dosing in the first cohort of the phase I/II BRILLIANCE study, which is evaluating EDIT-101 for LCA10. Editas is also pursuing the development of CRISPR candidates for eye diseases other than LCA10 including Usher Syndrome type 2A and recurrent ocular Herpes Simplex Virus type 1.

CRISPR Therapeutics' lead pipeline candidate CTX001, a CRISPR gene-edited therapy, is being developed in phase I/II studies for treating sickle cell disease and transfusion-dependent beta thalassemia in collaboration with Vertex.

In May, Fate Therapeutics got FDA clearance for its IND application to begin clinical studies on FT538, its first CRISPR-edited, iPSC-derived cell therapy. Enrollment is ongoing in phase I studies on FT538 as a monotherapy in AML and in combination with daratumumab, a CD38-directed monoclonal antibody therapy in multiple myeloma.

All these companies have the potential for long-term gains as they are developing drugs using innovative technologies. If their drugs are successfully developed and commercialized, the companies may see astronomical revenues.

It is therefore a good idea to add a few such stocks to your portfolio as they may give great returns in the next 2-3 years. Investors, at the same time, should keep in mind that investing in these biotech stocks is risky as either these companies make it or don't depending on whether the FDA approves their innovative medicines.

While CRISPR Therapeutics, Fate Therapeutics and Editas have a Zacks Rank #3 (Hold), Intellia has a Zacks Rank #4 (Sell).

You can see the complete list of today's Zacks #1 Rank (Strong Buy) stocks here.

More Stock News: This Is Bigger than the iPhone!

It could become the mother of all technological revolutions. Apple sold a mere 1 billion iPhones in 10 years but a new breakthrough is expected to generate more than 27 billion devices in just 3 years, creating a $1.7 trillion market.

Zacks has just released a Special Report that spotlights this fast-emerging phenomenon and 6 tickers for taking advantage of it. If you don't buy now, you may kick yourself in 2021. 

Click here for the 6 trades >>

Media Contact

Zacks Investment Research

800-767-3771 ext. 9339

support@zacks.com                                      

https://www.zacks.com                                          

 

Past performance is no guarantee of future results. Inherent in any investment is the potential for loss. This material is being provided for informational purposes only and nothing herein constitutes investment, legal, accounting or tax advice, or a recommendation to buy, sell or hold a security. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. It should not be assumed that any investments in securities, companies, sectors or markets identified and described were or will be profitable. All information is current as of the date of herein and is subject to change without notice. Any views or opinions expressed may not reflect those of the firm as a whole. Zacks Investment Research does not engage in investment banking, market making or asset management activities of any securities. These returns are from hypothetical portfolios consisting of stocks with Zacks Rank = 1 that were rebalanced monthly with zero transaction costs. These are not the returns of actual portfolios of stocks. The S&P 500 is an unmanaged index. Visit https://www.zacks.com/performance for information about the performance numbers displayed in this press release.


Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report
 
Vertex Pharmaceuticals Incorporated (VRTX) : Free Stock Analysis Report
 
Fate Therapeutics, Inc. (FATE) : Free Stock Analysis Report
 
Editas Medicine, Inc. (EDIT) : Free Stock Analysis Report
 
Intellia Therapeutics, Inc. (NTLA) : Free Stock Analysis Report
 
CRISPR Therapeutics AG (CRSP) : Free Stock Analysis Report
 
To read this article on Zacks.com click here.
 
Zacks Investment Research