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8. Crestor

Photo by: Astrazeneca
8. Crestor-
2010 US Sales: $3.8 billion Company: AstraZeneca Crestor is a cholesterol drug designed to help lower LDL (bad) cholesterol and raise HDL (good) cholesterol. It also slows the progressions of atherosclerosis, a condition that blocks arteries. Crestor is one of the most profitable drugs in AstraZeneca’s portfolio. The patent for Crestor expires in 2016, at which time generic competition will be fierce.

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