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Jane Kaczmarek

Jane Kaczmarek may be best known for being mom to a gaggle of rambunctious boys in the sitcom "Malcolm in the Middle," but in real life she didn't become a parent until the age of 41, when she gave birth to daughter Frances in 1997. She and now-ex-husband Bradley Whitford went on to have two more children, George, born when Kaczmarek was 44, and Mary, who the actress gave birth to at age 46.

First-Time Moms After 40

Halle Berry, Salma Hayek, and Mariah Carey are just a few of the celeb moms who entered motherhood after they turned the big 4-0. -- By Kathleen Perricone and Lizbeth Scordo, omg!