| 24.18% | % of Shares Held by All Insider |
| 28.85% | % of Shares Held by Institutions |
| 38.05% | % of Float Held by Institutions |
| 129 | Number of Institutions Holding Shares |
| Holder | Shares | Date Reported | % Out | Value |
|---|---|---|---|---|
| RTW Investments LP | 9,883,213 | Mar 30, 2019 | 7.36% | 29,353,142 |
| Blackrock Inc. | 8,375,522 | Mar 30, 2019 | 6.24% | 24,875,300 |
| Vanguard Group, Inc. (The) | 4,747,031 | Mar 30, 2019 | 3.54% | 14,098,682 |
| Shaw D.E. & Co., Inc. | 3,784,566 | Mar 30, 2019 | 2.82% | 11,240,161 |
| Artal Group S.A. | 2,750,000 | Mar 30, 2019 | 2.05% | 8,167,500 |
| State Street Corporation | 1,697,865 | Mar 30, 2019 | 1.26% | 5,042,659 |
| Oracle Investment Management Inc | 1,358,918 | Mar 30, 2019 | 1.01% | 4,035,986 |
| Geode Capital Management, LLC | 1,186,006 | Mar 30, 2019 | 0.88% | 3,522,437 |
| Northern Trust Corporation | 1,156,353 | Mar 30, 2019 | 0.86% | 3,434,368 |
| Oxford Asset Management Llp | 922,566 | Mar 30, 2019 | 0.69% | 2,740,021 |
| Holder | Shares | Date Reported | % Out | Value |
|---|---|---|---|---|
| Vanguard Total Stock Market Index Fund | 2,480,361 | Sep 29, 2018 | 1.85% | 5,307,972 |
| iShares Russell 2000 ETF | 1,977,015 | Mar 30, 2019 | 1.47% | 5,871,734 |
| Vanguard Extended Market Index Fund | 1,129,180 | Sep 29, 2018 | 0.84% | 2,416,445 |
| iShares Russell 2000 Growth ETF | 801,832 | Mar 30, 2019 | 0.60% | 2,381,441 |
| Fidelity Extended Market Index Fund | 473,851 | Mar 30, 2019 | 0.35% | 1,407,337 |
| Fidelity Small Cap Index Fund | 310,675 | Jan 30, 2019 | 0.23% | 1,046,974 |
| BlackRock Advantage Small Cap Growth Fund | 273,231 | Sep 29, 2018 | 0.20% | 584,714 |
| Schwab Strategic Tr-Schwab U.S. Small Cap ETF | 251,096 | Nov 29, 2018 | 0.19% | 605,141 |
| Fidelity Total Market Index Fund | 229,933 | Mar 30, 2019 | 0.17% | 682,901 |
| iShares Micro Cap ETF | 218,409 | Mar 30, 2019 | 0.16% | 648,674 |