| 49.80% | % of Shares Held by All Insider |
| 33.57% | % of Shares Held by Institutions |
| 66.86% | % of Float Held by Institutions |
| 121 | Number of Institutions Holding Shares |
| Holder | Shares | Date Reported | % Out | Value |
|---|---|---|---|---|
| Vivo Capital, LLC | 5,575,118 | Sep 29, 2018 | 11.07% | 44,266,436 |
| Ardsley Advisory Partners | 2,349,867 | Sep 29, 2018 | 4.67% | 18,657,943 |
| Blackrock Inc. | 2,277,432 | Sep 29, 2018 | 4.52% | 18,082,810 |
| Hood River Capital Management LLC | 1,507,606 | Sep 29, 2018 | 2.99% | 11,970,391 |
| Vanguard Group, Inc. (The) | 1,191,698 | Sep 29, 2018 | 2.37% | 9,462,082 |
| Gilder, Gagnon, Howe & Co. | 985,839 | Sep 29, 2018 | 1.96% | 7,827,561 |
| AWM Investment Company, Inc. | 740,000 | Sep 29, 2018 | 1.47% | 5,875,600 |
| Tanaka Capital Management Inc | 701,805 | Sep 29, 2018 | 1.39% | 5,572,331 |
| Allianz Asset Management AG | 643,630 | Sep 29, 2018 | 1.28% | 5,110,422 |
| Silverback Asset Management, LLC | 572,000 | Sep 29, 2018 | 1.14% | 4,541,680 |
| Holder | Shares | Date Reported | % Out | Value |
|---|---|---|---|---|
| iShares Russell 2000 ETF | 683,458 | Oct 30, 2018 | 1.36% | 5,091,762 |
| Vanguard Total Stock Market Index Fund | 609,083 | Sep 29, 2018 | 1.21% | 4,836,119 |
| Vanguard Extended Market Index Fund | 419,845 | Sep 29, 2018 | 0.83% | 3,333,569 |
| Roxbury/Hood River Small Cap Growth Fund | 380,785 | Sep 29, 2018 | 0.76% | 3,023,432 |
| iShares Russell 2000 Value ETF | 248,846 | Oct 30, 2018 | 0.49% | 1,853,902 |
| Invesco ETF Tr II-Invesco DWA Small Cap Momentum ETF | 211,890 | Oct 30, 2018 | 0.42% | 1,578,580 |
| Fidelity Extended Market Index Fund | 182,667 | Oct 30, 2018 | 0.36% | 1,360,869 |
| Bridgeway Funds Inc-Ultra Small Company Market Fund | 165,000 | Sep 29, 2018 | 0.33% | 1,310,100 |
| Fidelity Small Cap Index Fund | 93,177 | Oct 30, 2018 | 0.18% | 694,168 |
| iShares Micro Cap ETF | 79,295 | Oct 30, 2018 | 0.16% | 590,747 |