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Assembly Biosciences, Inc. (ASMB)

NasdaqGS - NasdaqGS Real Time Price. Currency in USD
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4.0400+0.1200 (+3.06%)
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Previous Close3.9200
Open3.9600
Bid4.0500 x 900
Ask4.0600 x 1100
Day's Range3.9000 - 4.0650
52 Week Range3.8400 - 27.8400
Volume405,731
Avg. Volume1,275,033
Market Cap161.839M
Beta (5Y Monthly)0.33
PE Ratio (TTM)N/A
EPS (TTM)-1.7540
Earnings DateFeb 25, 2021
Forward Dividend & YieldN/A (N/A)
Ex-Dividend DateN/A
1y Target Est11.40
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  • Assembly Biosciences (ASMB) Reports Q1 Loss, Lags Revenue Estimates
    Zacks

    Assembly Biosciences (ASMB) Reports Q1 Loss, Lags Revenue Estimates

    Assembly Biosciences (ASMB) delivered earnings and revenue surprises of 12.66% and -100.00%, respectively, for the quarter ended March 2021. Do the numbers hold clues to what lies ahead for the stock?

  • Assembly Biosciences Reports First Quarter 2021 Financial Results and Recent Updates
    GlobeNewswire

    Assembly Biosciences Reports First Quarter 2021 Financial Results and Recent Updates

    SOUTH SAN FRANCISCO, Calif., May 06, 2021 (GLOBE NEWSWIRE) -- Assembly Biosciences, Inc. (Nasdaq: ASMB), a clinical-stage biotechnology company developing innovative therapeutics targeting hepatitis B virus (HBV), today reported financial results and recent updates for the first quarter ended March 31, 2021. “In the first quarter of 2021, we solidified all our efforts and focus on hepatitis B and the sole pursuit of finite and curative therapies to replace burdensome life-long treatment regimens for the more than 250 million people living with this disease,” said John McHutchison, AO, MD, Chief Executive Officer and President of Assembly Bio. “Our strategy is clear and we have made significant progress, continuing to advance all our clinical programs while expanding and accelerating our novel discovery efforts. We are particularly excited that our first Phase 2 proof-of-concept triple combination studies – key drivers of our clinical strategy – are now underway.” Recent Updates Initiated two triple combination studies: Phase 2 study evaluating Assembly Bio’s lead core inhibitor candidate, vebicorvir (VBR), with standard-of-care nucleos(t)ide reverse transcriptase inhibitor (Nrtl) therapy and Arbutus Biopharma’s RNAi therapeutic candidate, AB-729Phase 2 study evaluating VBR with NrtI therapy and interferon (peg-IFNα) Anticipated Milestones and Events Nominate a fourth core inhibitor candidate with a best-in-class profile in Q2 2021Interim data from Phase 2 study with ABI-H2158 in H2 2021 Upcoming Conferences Chief Scientific Officer, William Delaney, PhD, to present at the Chronic Hepatitis B Drug Development Virtual Summit, May 6, 2021, during a session on “Targeting HBV Core Protein to Improve Treatment for cHBV patients.”Jefferies Global Healthcare Conference: June 1-3, 2021The International Liver Congress™(ILC), the Annual Meeting of the European Association for the Study of the Liver (EASL) taking place virtually June 23-26, 2021 Assembly Bio has three abstracts accepted for presentation: Enhanced potency and target coverage for both antiviral inhibition and cccDNA establishment of next generation core inhibitors ABI-H2158 and ABI-H3733Viral response and safety following treatment discontinuation in Study 211, the open-label extension study of VBR in combination with NrtI therapyNo emergent core inhibitor resistance in patients with chronic HBV infection treated with VBR in combination with NrtI First Quarter 2021 Financial Results Cash, cash equivalents and marketable securities were $214.9 million as of March 31, 2021, compared to $216.4 million as of December 31, 2020. This result includes $34.1 million of net proceeds from the issuance of common shares under Assembly Bio’s at-the-market (ATM) program. The company’s cash position is projected to fund operations into 2023.Revenues from collaborative research were $0 for the three months ended March 31, 2021, compared to $4.1 million for the same period in 2020. The decrease is due to the termination of the microbiome collaboration agreement with Allergan Pharmaceuticals following AbbVie Inc’s acquisition of Allergan. In Q1 2021 Assembly Bio completed the previously announced winddown of its microbiome program.Research and development expenses were $18.6 million for the three months ended March 31, 2021, compared to $23.0 million for the same period in 2020. The decrease is primarily due to a decrease of $8.2 million related to the wind-down of Assembly Bio’s microbiome program. This decrease was partially offset by an increase of $3.7 million in research and development expenses related to the company’s HBV program. Research and development expenses include non-cash stock-based compensation expenses of $(2.1) million for the three months ended March 31, 2021 and $1.9 million for the same period in 2020. The decrease is primarily due to the reversal of $2.4 million of previously recognized stock-based compensation expense related to forfeited awards of former microbiome program employees.General and administrative expenses were $8.7 million for both the three months ended March 31, 2021 and 2020. General and administrative expenses include non-cash stock-based compensation expenses of $1.8 million for the three months ended March 31, 2021 and $3.0 million for the same period in 2020.Net loss attributable to common stockholders was $27.2 million, or $0.69 per basic and diluted share, for the three months ended March 31, 2021, compared to $26.7 million, or $0.76 per basic and diluted share, for the same period in 2020. About Assembly BiosciencesAssembly Bio is a clinical-stage biotechnology company committed to bringing finite and curative therapies to the 270 million people living with hepatitis B virus (HBV) worldwide. A pioneer in the development of a new class of potent, oral core inhibitor drug candidates, Assembly Bio’s approach aims to break the complex viral replication cycle of HBV to free patients from a lifetime of therapy. Assembly Bio’s strategy toward cure includes a leading portfolio of more potent, next-generation core inhibitors, proof-of-concept combination studies and a research program focused on the discovery of novel HBV targets. For more information, visit assemblybio.com. Forward-Looking StatementsThe information in this press release contains forward-looking statements that are subject to certain risks and uncertainties that could cause actual results to materially differ. These risks and uncertainties include: Assembly Bio’s ability to initiate and complete clinical studies involving its therapeutic product candidates, including studies contemplated by Assembly Bio’s clinical collaboration agreements, in the currently anticipated timeframes; safety and efficacy data from clinical studies may not warrant further development of Assembly Bio’s product candidates; clinical and nonclinical data presented at conferences may not differentiate Assembly Bio’s product candidates from other companies’ candidates; continued development and commercialization of Assembly Bio’s product candidates, if successful, in the China territory will be dependent on, and subject to, Assembly Bio’s collaboration agreement governing its activity in the China territory; Assembly Bio’s ability to maintain financial resources necessary to continue its clinical studies and fund business operations; any impact that the COVID-19 pandemic may have on Assembly Bio’s business and operations, including initiation and continuation of its clinical studies or timing of discussions with regulatory authorities; and other risks identified from time to time in Assembly Bio’s reports filed with the U.S. Securities and Exchange Commission (the SEC). You are urged to consider statements that include the words may, will, would, could, should, might, believes, hopes, estimates, projects, potential, expects, plans, anticipates, intends, continues, forecast, designed, goal or the negative of those words or other comparable words to be uncertain and forward-looking. Assembly Bio intends such forward-looking statements to be covered by the safe harbor provisions contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. More information about Assembly Bio’s risks and uncertainties are more fully detailed under the heading “Risk Factors” in Assembly Bio’s filings with the SEC, including its most recent Annual Report on Form 10-K, Quarterly Reports on Form 10-Q and Current Reports on Form 8-K. Except as required by law, Assembly Bio assumes no obligation to update publicly any forward-looking statements, whether as a result of new information, future events or otherwise. ContactsInvestor and Corporate:Lauren GlaserSenior Vice President, Investor Relations and Corporate Affairs(415) 521-3828lglaser@assemblybio.com Media:Sam Brown Inc. Audra Friis (917) 519-9577 ASMBMedia@sambrown.com ASSEMBLY BIOSCIENCES, INC. CONDENSED CONSOLIDATED BALANCE SHEETS (In thousands except for share amounts and par value) March 31, December 31, 2021 2020 (Unaudited) ASSETS Current assets Cash and cash equivalents $78,253 $59,444 Marketable securities 136,631 156,969 Accounts receivable from collaborations 203 1,230 Prepaid expenses and other current assets 6,547 6,850 Total current assets 221,634 224,493 Property and equipment, net 1,493 1,600 Operating lease right-of-use (ROU) assets 8,104 9,131 Other assets 6,034 6,392 Indefinite-lived intangible asset 29,000 29,000 Goodwill 12,638 12,638 Total assets $ 278,903 $ 283,254 LIABILITIES AND STOCKHOLDERS' EQUITY Current liabilities Accounts payable $3,562 $4,598 Accrued clinical expenses 4,342 4,444 Other accrued expenses 3,659 11,987 Operating lease liabilities - short-term 2,934 3,404 Total current liabilities 14,497 24,433 Deferred tax liabilities 2,531 2,531 Deferred revenue 8,987 8,987 Operating lease liabilities - long-term 5,644 6,725 Total liabilities 31,659 42,676 Commitments and contingencies Stockholders' equity Preferred stock, $0.001 par value; 5,000,000 shares authorized; no shares issued or outstanding — — Common stock, $0.001 par value; 100,000,000 shares authorized as of March 31, 2021 and December 31, 2020; 40,104,684 and 34,026,680 shares issued and outstanding as of March 31, 2021 and December 31, 2020, respectively 40 34 Additional paid-in capital 776,248 742,387 Accumulated other comprehensive loss (271) (270) Accumulated deficit (528,773) (501,573) Total stockholders' equity 247,244 240,578 Total liabilities and stockholders' equity $ 278,903 $ 283,254 ASSEMBLY BIOSCIENCES, INC. CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (In thousands except for share and per share amounts) (Unaudited) Three Months Ended March 31, 2021 2020 Collaboration revenue $— $4,081 Operating expenses: Research and development 18,554 23,046 General and administrative 8,704 8,729 Total operating expenses 27,258 31,775 Loss from operations (27,258) (27,694) Other income: Interest and other income, net 58 1,039 Total other income 58 1,039 Net loss $ (27,200) $ (26,655) Other comprehensive (loss) income Unrealized (loss) gain on marketable securities (1) 115 Comprehensive loss $ (27,201) $ (26,540) Net loss per share, basic and diluted $(0.69) $(0.76) Weighted average common shares outstanding, basic and diluted 39,679,734 35,079,756

  • Earnings Preview: Assembly Biosciences (ASMB) Q1 Earnings Expected to Decline
    Zacks

    Earnings Preview: Assembly Biosciences (ASMB) Q1 Earnings Expected to Decline

    Assembly Biosciences (ASMB) doesn't possess the right combination of the two key ingredients for a likely earnings beat in its upcoming report. Get prepared with the key expectations.