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Cyclerion Therapeutics, Inc. (CYCN)

NasdaqGS - NasdaqGS Real Time Price. Currency in USD
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2.5800+0.0800 (+3.20%)
At close: 4:00PM EDT

2.5600 -0.02 (-0.78%)
After hours: 5:52PM EDT

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Previous Close2.5000
Open2.5200
Bid2.5600 x 1300
Ask2.6000 x 1800
Day's Range2.3800 - 2.6050
52 Week Range2.1800 - 8.9600
Volume457,864
Avg. Volume711,288
Market Cap87.861M
Beta (5Y Monthly)2.06
PE Ratio (TTM)N/A
EPS (TTM)-2.5590
Earnings DateFeb 25, 2021
Forward Dividend & YieldN/A (N/A)
Ex-Dividend DateN/A
1y Target EstN/A
Fair Value is the appropriate price for the shares of a company, based on its earnings and growth rate also interpreted as when P/E Ratio = Growth Rate. Estimated return represents the projected annual return you might expect after purchasing shares in the company and holding them over the default time horizon of 5 years, based on the EPS growth rate that we have projected.
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(NASDAQ: FHTX) (issued a corporate update) Galecto, Inc. (NASDAQ: GLTO) Voyager Therapeutics, Inc. (NASDAQ: VYGR) Stocks In Focus Sarepta Presents Positive Data For Gene Therapy to Treat Limb-gridle Muscular Dystrophy Sarepta Therapeutics, Inc. (NASDAQ: SRPT) announced new results from the ongoing study of SRP-9003, its investigational gene therapy for limb-girdle muscular dystrophy Type 2E, showing sustained protein expression in muscle tissue. Functional assessments taken two years following treatment in low-dose arm and one year after treatment in high-dose arm showed that patients continued to demonstrate stability in their NSAD total score and improvements on timed function tests. Results in both cohorts continue to reinforce the safety and tolerability profile of SRP-9003, the company said. The results were presented today at the 2021 Muscular Dystrophy Association Annual Clinical and Scientific Conference. In after-hours trading, the stock added 4.75% to $87.75. Cyclerion Announces Departure of Chief Medical Officer Cyclerion Therapeutics, Inc. (NASDAQ: CYCN) said Christopher Wright, its chief medical officer, has resigned his position with the company. Wright will provide Cyclerion with transitional support until March 26, and will also join the company's Clinical Advisory Board. vTv Commences Study to Evaluate Potential of TTP399 In Reducing Ketoacidosis In Type 1 Diabetes Patients vTv Therapeutics Inc. (NASDAQ: VTVT) announced the initiation of a mechanistic study exploring the effects of TTP399 on ketone body formation during a period of insulin withdrawal in people with type 1 diabetes. The phase 1 study, the company said, will test the hypothesis that treatment with vTv's TTP399 will not result in the increased production of ketones, a precursor to ketoacidosis, which can lead to hospitalization in patients with type 1 diabetes. Diabetic ketoacidosis is a serious complication of diabetes that occurs when the body produces high levels of blood acids called ketones when insulin production by the body is inadequate. The stock lost 3.91% to $2.70 in after-hours trading. Incyte's Jakafi Flunks a Late-stage Study In Treating ARDS In COVID-19 Patients Incyte Corporation (NASDAD: INCY) said the Phase 3 DEVENT study evaluating the efficacy and safety of Jakafi, 5mg and 16mg doses, plus standard-of-care versus SoC in patients on mechanical ventilation with COVID-19 associated Acute Respiratory Distress Syndrome did not meet its primary endpoint. Improvement in mortality for each dose compared to placebo, while trending toward positive, was not statistically significant for the overall study population, the company said. However, significant improvement in mortality was seen in U.S. study participants at both doses, and in the overall population when data from both treatment arms was pooled. The company said it will discuss with the FDA regarding an expanded access program to allow eligible patients in the U.S. with COVID-19-associated ARDS to receive ruxolitinib. In after-hours trading, the stock rose 1.06% to $79.08 in after-hours trading. Idera Says Lead Drugs Flunks Late-Stage Skin Cancer Study Idera Pharmaceuticals, Inc. (NASDAQ: IDRA) said the ILLUMINATE-301 pivotal registration trial of its lead product candidate tilsotolimod in combination with Bristol-Myers Squibb Company's (NYSE: BMY) Yervoy versus ipilimumab alone in patients with anti-PD-1 refractory advanced melanoma, did not meet its primary endpoint of objective response rate. Idera said it is evaluating its next steps regarding continuation of the trial toward its overall survival endpoint, which includes evaluating the full data set when it is available. The company also plans to continue its ILLUMINATE-206 Phase 2 study of tilsotolimod in combination with ipilimumab and nivolumab in patients with microsatellite stable colorectal cancer. View more earnings on IBB The stock plunged 59.88% to $2.01 in after-hours trading. Merck, Eisai Report Positive Late-Stage Data For Combo Therapy In Endometrial Cancer Merck (NYSE: MRK) and Eisai Co., Ltd. (OTC: ESALY) announced positive data from the pivotal Phase 3 KEYNOTE-775/Study 309 trial that evaluated the combination of the former's Keytruda plus the latter's Lenvima, for the treatment of certain patients with advanced, metastatic or recurrent endometrial cancer following one prior platinum-based regimen in any setting. The data was presented in an oral plenary session at the virtual Society of Gynecologic Oncology 2021 Annual Meeting on Women's Cancer. Kiniksa Announces FDA Approval for Arcalyst In Treating Autoinflammatory Cardiovascular Disease Kiniksa Pharmaceuticals, Ltd. (NASDAQ: KNSA) said the FDA approved Arcalyst, a weekly, subcutaneously-injected, recombinant fusion protein, for the treatment of recurrent pericarditis and reduction in risk of recurrence in adults and children 12 years and older. The company expects to launch the drug in April 2021. The stock gained 10.50% to $24 in after-hours trading. Marker Therapeutics Gains On Insider Buying Marker Therapeutics, Inc. (NASDAQ: MRKR) shares moved to the upside after a series of filings by the company revealed company insiders bought shares in the company. The stock was up 21.11% to $2.18 in after-hours trading. Earnings Alpine Immune Sciences, Inc. (NASDAQ: ALPN) reported an increase in its fourth-quarter revenues from $884,000 in 2019 to $5.64 million in 2020. The net loss per share narrowed from 33 cents to 27 cents. The stock slipped 5.87% to $13 in after-hours trading. On The Radar Clinical Readouts The Society of Gynecologic Oncology Meeting Presentations Aravive, Inc. (NASDAQ: ARAV): Updated data from the Phase 1b trial evaluating AVB-500 in platinum resistant ovarian cancer (3:35 pm); Additionally, a trial in progress poster is to be presented on the Phase 1/2 investigator-sponsored trial of AVB-500 in combination with durvalumab in patients with platinum resistant, recurrent epithelial ovarian cancer. Leap Therapeutics, Inc. (NASDAQ: LPTX): Additional data from the Phase 2 study of DKN-01 and Paclitaxel chemotherapy medication in endometrial cancer Earnings Celsion Corporation (NASDAQ: CLSN) IPOs Finch Therapeutics Group, Inc, a clinical-stage microbiome therapeutics company developing a novel class of orally administered biological drugs, priced its upsized initial public offering of 7.5 million shares of common stock at $17 per share, for raising gross proceeds of $127.5 million. The shares will begin trading on the Nasdaq under the ticker symbol FNCH. China-based biopharma Connect Biopharma Holdings Ltd priced its IPO of 11.25 million ADSs, representing 11.25 million ordinary shares of the company, at $17 per ADS. The gross proceeds from the offering are expected to be $191.3 million. The ADSs of the company that is developing T-cell therapies for chronic inflammatory diseases will begin trading on the Nasdaq under the ticker symbol CNTB. Instil Bio, Inc., a clinical-stage biopharmaceutical company that develops an innovative cell therapy pipeline of autologous TIL therapies for the treatment of patients with cancer, priced its upsized initial public offering of 16 million shares of common stock at $20 per share. The gross proceeds of the offering, are expected to be $320 million. The shares are expected to begin trading on the Nasdaq under the symbol TIL. Related Link: Attention Biotech Investors: Mark Your Calendar For March PDUFA Dates See more from BenzingaClick here for options trades from BenzingaThe Daily Biotech Pulse: Translate Bio's Cystic Fibrosis Study Disappoints, Adverum Nominates Directors, Gain Therapeutics To Debut On NasdaqThe Daily Biotech Pulse: Merck's Keytruda Gets Label Expansion In Europe, Pfizer To Sell Chinese Biologics Unit, Celcuity Spikes© 2021 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.