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Foghorn Therapeutics Inc. (FHTX)

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Previous Close19.41
Open19.63
Bid19.47 x 900
Ask19.89 x 1000
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52 Week Range14.03 - 28.26
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Market Cap715.455M
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    • Foghorn Therapeutics Announces Third Quarter 2020 Financial Results and Provides Corporate Update
      GlobeNewswire

      Foghorn Therapeutics Announces Third Quarter 2020 Financial Results and Provides Corporate Update

      – Well positioned to advance broad pipeline with recent completion of IPO and Merck collaboration – On track to submit an IND for FHD-286 by year end 2020 and for FHD-609 during the first half of 2021 – Strengthened management team with the appointment of Michael LaCascia as Chief Legal Officer CAMBRIDGE, Mass., Dec. 04, 2020 (GLOBE NEWSWIRE) -- December 4, 2020—Foghorn Therapeutics Inc. (Nasdaq: FHTX), a company pioneering the discovery and development of a new class of medicines targeting genetically determined dependencies within the chromatin regulatory system, today reported financial results for the third quarter ended September 30, 2020 and provided a corporate update. “This is an eventful period for Foghorn as the company is on the cusp of transitioning our first two compounds into clinical studies,” said Adrian Gottschalk, CEO of Foghorn. “We expect our first IND for FHD-286 to be submitted before the end of this year. In addition, our first degrader program, FHD-609, remains on track for an IND filing in the first half of next year. We have raised $240 million this year through a private financing round, subsequent IPO and our Merck collaboration, positioning the company to advance our broad pipeline targeting the chromatin regulatory system.”Recent Corporate Highlights * Completed $135 Million Initial Public Offering: In October 2020, Foghorn sold 7,500,000 shares of common stock at a public offering price of $16 per share. In November 2020, the underwriters exercised their option to purchase an additional 951,837 shares of common stock at the public offering price. The gross proceeds of the offering, before deducting underwriting discounts and commissions and other offering expenses payable by Foghorn, were $135.2 million. * Entered into collaboration agreement with Merck to discover and develop novel oncology therapeutics against a transcription factor target: Under the terms of the agreement, signed in July 2020, Foghorn received a $15 million upfront payment and is eligible to receive up to an additional $410 million in development, regulatory and commercial milestones as well as royalties on product sales if products are successfully developed and commercialized under the collaboration. * Strengthened management team: In November 2020, Foghorn appointed Michael LaCascia as Chief Legal Officer. Key Upcoming Milestones * FHD-286 IND submission expected by year end 2020: FHD-286, a highly potent, selective, allosteric, orally available small molecule enzymatic inhibitor is initially being developed in acute myelogenous leukemia and uveal melanoma. The company remains on track to submit an Investigational New Drug (IND) to the FDA by year end. * FHD-609 IND submission expected in the first half of 2021: FHD-609, a highly potent, selective, intravenous, small molecule protein degrader of BRD9 is initially being developed for the treatment of synovial sarcoma with the intention to expand into indications beyond synovial sarcoma, including SMARCB1-deleted tumors. The company remains on track to file an IND with the FDA in the first half of 2021. Third Quarter 2020 Financial Results * Cash Position and Financial Guidance: Cash and cash equivalents as of September 30, 2020 were $74.6 million, compared to $15.0 million as of December 31, 2019. The September 30, 2020 cash and equivalents excludes $122.2 million in net proceeds from our initial public offering, which was completed in October 2020. * Revenues: Collaboration revenues for the third quarter of 2020 were $0.2 million, compared to no revenue for the third quarter of 2019, which reflects revenue recognized under our research collaboration agreement with Merck which was entered into in July 2020. * Research and Development (R&D) Expenses: R&D expenses for the third quarter of 2020 were $16.1 million, compared to $11.3 million for the third quarter of 2019. The increase in R&D expenses was primarily attributable to higher preclinical costs related to our first two programs and increased personnel to support our research and development activities. * General and Administrative (G&A) Expenses: G&A expenses for the third quarter of 2020 were $2.6 million, compared to $1.8 million for the third quarter of 2019. The increase in G&A expenses was primarily attributable to an increase in headcount in our general and administrative functions to support our business. * Net Loss: Net loss attributable to common stockholders was $18.4 million, or $3.12 per share, for the quarter ended September 30, 2020, compared to $13.1 million, or $3.05 per share, for the quarter ended September 30, 2019. Foghorn Therapeutics Inc. Condensed Consolidated Balance Sheet Data(In thousands)(Unaudited)    September 30,  December 31,    2020  2019  Cash and cash equivalents $74,620  $14,981  Total assets  142,428   22,342  Notes payable, net of discount  14,791   15,112  Deferred revenue  14,821   —  Total stockholders' deficit  (133,323)  (88,016) Foghorn Therapeutics, Inc.Condensed Consolidated Statements of Operations and Comprehensive Loss(In thousands, except share and per share amounts)(Unaudited)  Three Months Ended September 30,  Nine Months Ended September 30,    2020  2019  2020  2019  Collaboration revenue $179  $—  $179  $—  Operating expenses:                 Research and development  16,113   11,292   41,244   30,842  General and administrative  2,555   1,808   6,687   5,056  Total operating expenses  18,668   13,100   47,931   35,898  Loss from operations  (18,489)  (13,100)  (47,752)  (35,898) Other income (expense):                 Interest expense  (202)  (113)  (658)  (362) Interest income and other income (expense), net  394   121   437   424  Change in fair value of preferred stock warrant liability  (70)  —   (69)  —  Total other income (expense), net  122   8   (290)  62  Net loss and comprehensive loss $(18,367) $(13,092) $(48,042) $(35,836) Net loss per share attributable to common                 stockholders—basic and diluted $(3.12) $(3.05) $(8.76) $(8.96) Weighted average common shares                 outstanding—basic and diluted  5,884,027   4,294,663   5,487,154   4,000,939                    About Foghorn TherapeuticsFoghorn® Therapeutics is discovering and developing a novel class of medicines targeting genetically determined dependencies within the chromatin regulatory system. Through its proprietary scalable Gene Traffic Control® platform, Foghorn is systematically studying, identifying and validating potential drug targets within the chromatin regulatory system. The company is developing multiple product candidates in oncology and expects to file an IND for its first program later this year.Forward-Looking StatementsThis press release contains “forward-looking statements” regarding the Company’s recent corporate highlights, including the collaboration agreement with Merck, and key upcoming milestones. Forward-looking statements include statements regarding the proposed public offering and other statements identified by words such as “could,” “may,” “might,” “will,” “likely,” “anticipates,” “intends,” “plans,” “seeks,” “believes,” “estimates,” “expects,” “continues,” “projects” and similar references to future periods. Forward-looking statements are based on our current expectations and assumptions regarding capital market conditions, our business, the economy and other future conditions. Because forward-looking statements relate to the future, by their nature, they are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict. As a result, actual results may differ materially from those contemplated by the forward-looking statements. Important factors that could cause actual results to differ materially from those in the forward-looking statements include regional, national or global political, economic, business, competitive, market and regulatory conditions, including risk regarding the timing of filing an IND and other factors set forth under the heading “Risk Factors” in the Company’s registration statement on Form S-1. Any forward-looking statement made in this press release speaks only as of the date on which it is made.Media Contact:Fanny Cavalié, Foghorn Therapeutics fcavalie@foghorntx.comGregory Kelley, Ogilvy gregory.kelley@ogilvy.comInvestor Relations Contact:Allan Reine, Foghorn Therapeutics areine@foghorntx.com

    • Foghorn Therapeutics Appoints Michael LaCascia as Chief Legal Officer
      GlobeNewswire

      Foghorn Therapeutics Appoints Michael LaCascia as Chief Legal Officer

      CAMBRIDGE, Mass., Nov. 12, 2020 (GLOBE NEWSWIRE) -- Foghorn Therapeutics Inc. (Nasdaq: FHTX), a company pioneering the discovery and development of a new class of medicines targeting genetically determined dependencies within the chromatin regulatory system, today announced the appointment of Michael LaCascia as its Chief Legal Officer. An accomplished attorney, Mr. LaCascia joins Foghorn with extensive corporate, securities, governance, and transactional expertise within the biotechnology industry. “The deep and proven experience Mike has across a wide range of legal and corporate matters in the life sciences sector will be invaluable to us as we move forward as a newly public company,” said Adrian Gottschalk, President and Chief Executive Officer of Foghorn. “Mike is an important addition to the leadership team as Foghorn transitions to a clinical-stage company with multiple high value programs and reinforces our commitment to establishing the strongest team possible to fully realize the promise of our Gene Traffic Control platform.”Prior to joining Foghorn, Mr. LaCascia served as Senior Vice President and Chief Legal Officer of Q-State Biosciences, Inc., where he helped lead the transition of the company’s strategy from enabling discovery services to the discovery of its own proprietary therapeutics. He previously served as Senior Vice President, General Counsel and Secretary for Vertex Pharmaceuticals where he oversaw its global legal function and corporate governance. Mr. LaCascia also spent more than two decades at the firm WilmerHale LLP, where he was a partner in the firm’s corporate practice and specialized in securities, mergers and acquisitions, and corporate governance matters. Mr. LaCascia received his J.D. from Boston University Law School and a B.A. in Economics from Harvard College.“I am thrilled to be joining Foghorn at this important time in the company’s evolution,” said Mr. LaCascia. “Foghorn has assembled an outstanding leadership team and a talented group of professionals who have quickly established the company as pioneers of a new class of potential medicines targeting breakdowns in the chromatin regulatory system. I look forward to contributing to the continued success of the company and helping to bring its breakthrough medicines to patients.”About Foghorn TherapeuticsFoghorn® Therapeutics is discovering and developing a novel class of medicines targeting genetically determined dependencies within the chromatin regulatory system. Through its proprietary scalable Gene Traffic Control™ platform, Foghorn is systematically studying, identifying and validating potential drug targets within the chromatin regulatory system. The company is developing multiple product candidates in oncology and expects to file an IND for its first program later this year.Forward-Looking Statements This press release contains “forward-looking statements” regarding the Company’s plans for its proposed initial public offering. Forward-looking statements include statements regarding the proposed public offering and other statements identified by words such as “could,” “may,” “might,” “will,” “likely,” “anticipates,” “intends,” “plans,” “seeks,” “believes,” “estimates,” “expects,” “continues,” “projects” and similar references to future periods. Forward-looking statements are based on our current expectations and assumptions regarding capital market conditions, our business, the economy and other future conditions. Because forward-looking statements relate to the future, by their nature, they are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict. As a result, actual results may differ materially from those contemplated by the forward-looking statements. Important factors that could cause actual results to differ materially from those in the forward-looking statements include regional, national or global political, economic, business, competitive, market and regulatory conditions, including risk regarding when we can complete the offering and other factors set forth under the heading “Risk Factors” in the Company’s registration statement on Form S-1. Any forward-looking statement made in this press release speaks only as of the date on which it is made.MEDIA CONTACTFanny Cavalié, Foghorn Therapeutics fcavalie@foghorntx.comGregory Kelley, Ogilvy gregory.kelley@ogilvy.comINVESTOR RELATIONS CONTACT Allan Reine, Foghorn Therapeutics areine@foghorntx.com

    • GlobeNewswire

      Foghorn Therapeutics Announces Pricing of Initial Public Offering

      CAMBRIDGE, Mass., Oct. 22, 2020 (GLOBE NEWSWIRE) -- Foghorn Therapeutics Inc. (Nasdaq: FHTX), a company pioneering the discovery and development of a new class of medicines targeting genetically determined dependencies within the chromatin regulatory system, today announced the pricing of its initial public offering of 7,500,000 shares of its common stock at a public offering price of $16.00 per share. All of the shares are being offered by Foghorn. In addition, Foghorn has granted the underwriters a 30-day option to purchase up to an additional 1,125,000 shares of common stock at the initial public offering price, less the underwriting discounts and commissions. Foghorn’s common stock is expected to begin trading on The Nasdaq Global Market on October 23, 2020 under the symbol “FHTX.” The gross proceeds of the offering, before deducting underwriting discounts and commissions and other estimated offering expenses payable by Foghorn, are expected to be approximately $120 million excluding any exercise of the underwriters’ option to purchase additional shares. The offering is expected to close on October 27, 2020, subject to the satisfaction of customary closing conditions.Goldman Sachs & Co. LLC, Morgan Stanley and Cowen are acting as joint book-running managers for the offering, and Wedbush PacGrow is acting as co-manager.A registration statement relating to the shares being sold in this offering was declared effective by the Securities and Exchange Commission on October 22, 2020. The offering is being made only by means of a prospectus, copies of which may be obtained from Goldman Sachs & Co. LLC, Attention: Prospectus Department, 200 West Street, New York, NY 10282, or by telephone at (866) 471-2526, or by email at prospectus-ny@ny.email.gs.com; Morgan Stanley & Co. LLC, Attention: Prospectus Department, 180 Varick Street, 2nd Floor, New York, NY 10014; or Cowen and Company, LLC, c/o Broadridge Financial Solutions, Attention: Prospectus Department, 1155 Long Island Avenue, Edgewood, NY 11717, or by telephone at (833) 297-2926, or by email at PostSaleManualRequests@broadridge.com.This press release shall not constitute an offer to sell or a solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or other jurisdiction.About Foghorn TherapeuticsFoghorn® Therapeutics is discovering and developing a novel class of medicines targeting genetically determined dependencies within the chromatin regulatory system. Through its proprietary scalable Gene Traffic Control™ platform, Foghorn is systematically studying, identifying and validating potential drug targets within the chromatin regulatory system. The company is developing multiple product candidates in oncology and expects to file an IND for its first program later this year.Foghorn was founded in 2015 by Cigall Kadoch, Ph.D., Gerald Crabtree, M.D., and Doug Cole, M.D., of Flagship Pioneering.Forward-Looking Statements This press release contains “forward-looking statements” regarding the Company’s plans for its proposed initial public offering. Forward-looking statements include statements regarding the proposed public offering and other statements identified by words such as “could,” “may,” “might,” “will,” “likely,” “anticipates,” “intends,” “plans,” “seeks,” “believes,” “estimates,” “expects,” “continues,” “projects” and similar references to future periods. Forward-looking statements are based on our current expectations and assumptions regarding capital market conditions, our business, the economy and other future conditions. Because forward-looking statements relate to the future, by their nature, they are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict. As a result, actual results may differ materially from those contemplated by the forward-looking statements. Important factors that could cause actual results to differ materially from those in the forward-looking statements include regional, national or global political, economic, business, competitive, market and regulatory conditions, including risk regarding when we can complete the offering and other factors set forth under the heading “Risk Factors” in the Company’s registration statement on Form S-1. Any forward-looking statement made in this press release speaks only as of the date on which it is made.MEDIA CONTACTFanny Cavalié, Foghorn Therapeutics fcavalie@foghorntx.com