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Global Blood Therapeutics, Inc. (GBT)

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42.32-1.71 (-3.88%)
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Previous Close44.03
Open44.10
Bid38.00 x 800
Ask0.00 x 900
Day's Range42.32 - 44.43
52 Week Range36.49 - 83.69
Volume599,769
Avg. Volume1,141,596
Market Cap2.63B
Beta (5Y Monthly)1.10
PE Ratio (TTM)N/A
EPS (TTM)-4.04
Earnings DateMay 04, 2021 - May 10, 2021
Forward Dividend & YieldN/A (N/A)
Ex-Dividend DateN/A
1y Target Est84.63
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  • GBT Opens 2021 ACCEL Grant Program, Providing up to $500,000 in Support to the Sickle Cell Disease Community
    GlobeNewswire

    GBT Opens 2021 ACCEL Grant Program, Providing up to $500,000 in Support to the Sickle Cell Disease Community

    Grant proposals from community-based organizations and institutions accepted through April 23, 2021SOUTH SAN FRANCISCO, Calif., March 02, 2021 (GLOBE NEWSWIRE) -- Global Blood Therapeutics, Inc. (GBT) (NASDAQ: GBT) today announced that it is accepting proposals for the third annual Access to Excellent Care for Sickle Cell Patients (ACCEL) Grant Program, which provides funding to accelerate the development of sustainable access-to-care programs for people living with sickle cell disease (SCD). This year, the program is doubling the total funding and number of grantees by awarding 10 grants worth up to $50,000 each. GBT will accept proposals from community-based organizations and institutions with programs designed to make it easier for patients to get SCD care and ensure that providers deliver the highest quality care possible. “GBT is driven by our mission to transform the lives of people living with sickle cell disease, and we recognize, now more than ever, that means increasing our support of the sickle cell community,” said Jung E. Choi, chief business and strategy officer, and head of patient advocacy and government affairs at GBT. “That is why, this year, we are doubling our efforts to fund novel programs that address the inequities people with sickle cell disease face gaining access to high-quality, continuous healthcare, as well as meeting the unique needs during the COVID-19 pandemic. We are proud of the work past grantees have accomplished and look forward to supporting more organizations that are making a difference in the lives of people with this devastating disease.” In previous years, the ACCEL program has selected and funded up to $250,000 to five U.S. community-based organizations and institutions serving patients with SCD and their families. With the doubling of funds for 2021, this year’s priority areas for grant proposals have expanded to include initiatives that address racial equity and COVID-19 vaccine awareness amongst the SCD community. Other priority areas include educational initiatives focused on patient empowerment, shared decision-making and enabling navigation of the healthcare system; improving transition from pediatric to adult care; community outreach models using health workers to directly facilitate access to care; and innovative training programs and outreach models. GBT is accepting proposals for the ACCEL program through Friday, April 23, 2021, at 11:59 p.m. Pacific time. A panel of GBT management and external stakeholders with expertise in the issues affecting people with SCD will review proposal submissions. The panel will select grant recipients based on the proposal’s goals and objectives, potential impact and overall strength of the work plan, timeline, evaluation plan and organizational capabilities. More information about the ACCEL program and how to submit a proposal can be found here. About Sickle Cell DiseaseSickle cell disease (SCD) affects an estimated 100,000 people in the United States,1 an estimated 52,000 people in Europe,2 and millions of people throughout the world, particularly among those whose ancestors are from sub-Saharan Africa.1 It also affects people of Hispanic, South Asian, Southern European and Middle Eastern ancestry.1 SCD is a lifelong inherited rare blood disorder that impacts hemoglobin, a protein carried by red blood cells that delivers oxygen to tissues and organs throughout the body.3 Due to a genetic mutation, individuals with SCD form abnormal hemoglobin known as sickle hemoglobin. Through a process called hemoglobin polymerization, red blood cells become sickled – deoxygenated, crescent-shaped and rigid.3-5 The sickling process causes hemolytic anemia (low hemoglobin due to red blood cell destruction) and blockages in capillaries and small blood vessels, which impede the flow of blood and oxygen throughout the body. The diminished oxygen delivery to tissues and organs can lead to life-threatening complications, including stroke and irreversible organ damage.4-7 About Global Blood TherapeuticsGlobal Blood Therapeutics (GBT) is a biopharmaceutical company dedicated to the discovery, development and delivery of life-changing treatments that provide hope to underserved patient communities. Founded in 2011, GBT is delivering on its goal to transform the treatment and care of sickle cell disease (SCD), a lifelong, devastating inherited blood disorder. The company has introduced Oxbryta® (voxelotor) tablets, the first FDA-approved treatment that directly inhibits sickle hemoglobin polymerization, the root cause of red blood cell sickling in SCD. GBT is also advancing its pipeline program in SCD with inclacumab, a P-selectin inhibitor in development to address pain crises associated with the disease, and GBT021601 (GBT601), the company’s next generation hemoglobin S polymerization inhibitor. In addition, GBT’s drug discovery teams are working on new targets to develop the next wave of treatments for SCD. To learn more, please visit www.gbt.com and follow the company on Twitter @GBT_news. Forward-Looking StatementsCertain statements in this press release are forward-looking within the meaning of the Private Securities Litigation Reform Act of 1995, including statements containing the words “will,” “anticipates,” “plans,” “believes,” “forecast,” “estimates,” “expects” and “intends,” or similar expressions. These forward-looking statements are based on GBT’s current expectations and actual results could differ materially. Statements in this press release may include statements that are not historical facts and are considered forward-looking within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. GBT intends these forward-looking statements, including statements regarding GBT’s priorities, dedication, commitment, focus, goals, mission and vision; the ACCEL Grant Program, including the related activities, priority areas and expectations; safety, efficacy and mechanism of action of Oxbryta and other product characteristics; significance of reducing hemolysis and raising hemoglobin; commercialization, delivery, availability, use and commercial and medical potential of Oxbryta; ongoing and planned studies and related protocols, activities and expectations; altering the treatment, course and care of SCD and transforming the lives of people living with SCD; potential and advancement of GBT’s pipeline, including inclacumab and other product candidates; and working on new targets and discovering, developing and delivering treatments, to be covered by the safe harbor provisions for forward-looking statements contained in Section 27A of the Securities Act and Section 21E of the Securities Exchange Act, and GBT makes this statement for purposes of complying with those safe harbor provisions. These forward-looking statements reflect GBT’s current views about its plans, intentions, expectations, strategies and prospects, which are based on the information currently available to the company and on assumptions the company has made. GBT can give no assurance that the plans, intentions, expectations or strategies will be attained or achieved, and, furthermore, actual results may differ materially from those described in the forward-looking statements and will be affected by a variety of risks and factors that are beyond GBT’s control, including, without limitation, risks and uncertainties relating to the COVID-19 pandemic, including the extent and duration of the impact on GBT’s business, including commercialization activities, regulatory efforts, research and development, corporate development activities and operating results, which will depend on future developments that are highly uncertain and cannot be accurately predicted, such as the ultimate duration of the pandemic, travel restrictions, quarantines, social distancing and business closure requirements in the U.S. and in other countries, and the effectiveness of actions taken globally to contain and treat the disease; the risks that GBT is continuing to establish its commercialization capabilities and may not be able to successfully commercialize Oxbryta; risks associated with GBT’s dependence on third parties for development, manufacture, distribution and commercialization activities related to Oxbryta; government and third-party payor actions, including those relating to reimbursement and pricing; risks and uncertainties relating to competitive products and other changes that may limit demand for Oxbryta; the risks regulatory authorities may require additional studies or data to support continued commercialization of Oxbryta; the risks that drug-related adverse events may be observed during commercialization or clinical development; data and results may not meet regulatory requirements or otherwise be sufficient for further development, regulatory review or approval; compliance with obligations under the Pharmakon loan; and the timing and progress of GBT’s and Syros’ research and development activities under their collaboration; along with those risks set forth in GBT’s Annual Report on Form 10-K for the fiscal year ended December 31, 2020, filed with the U.S. Securities and Exchange Commission, as well as discussions of potential risks, uncertainties and other important factors in GBT’s subsequent filings with the U.S. Securities and Exchange Commission. Except as required by law, GBT assumes no obligation to update publicly any forward-looking statements, whether as a result of new information, future events or otherwise. References Centers for Disease Control and Prevention website. Sickle Cell Disease (SCD). https://www.cdc.gov/ncbddd/sicklecell/data.html. Accessed June 3, 2019.European Medicines Agency. https://www.ema.europa.eu/en/medicines/human/orphan-designations/eu3182125. Accessed June 12, 2020.National Heart, Lung, and Blood Institute website. Sickle Cell Disease. https://www.nhlbi.nih.gov/health-topics/sickle-cell-disease. Accessed August 5, 2019.Rees DC, et al. Lancet. 2010;376(9757):2018-2031.Kato GJ, et al. Nat Rev Dis Primers. 2018;4:18010.Kato GJ, et al. J Clin Invest. 2017;127(3):750-760.Caboot JB, et al. Paediatr Respir Rev. 2014;15(1):17-23. Contact:Steven Immergut (media)650.410.3258simmergut@gbt.com Courtney Roberts (investors)650.351.7881croberts@gbt.com

  • GBT Announces Participation at the H.C. Wainwright Global Life Sciences Conference
    GlobeNewswire

    GBT Announces Participation at the H.C. Wainwright Global Life Sciences Conference

    SOUTH SAN FRANCISCO, Calif., March 02, 2021 (GLOBE NEWSWIRE) -- Global Blood Therapeutics, Inc. (GBT) (NASDAQ: GBT) will participate at the H.C. Wainwright Global Life Sciences Conference on Tuesday, March 9, 2021. A presentation by Ted W. Love, M.D., president and CEO of GBT, will be available at 7:00 a.m. ET. The presentation will be available on GBT’s website at www.gbt.com in the Investors section. A replay will be available for one month following the event. About Global Blood Therapeutics Global Blood Therapeutics (GBT) is a biopharmaceutical company dedicated to the discovery, development, and delivery of life-changing treatments that provide hope to underserved patient communities. Founded in 2011, GBT is delivering on its goal to transform the treatment and care of sickle cell disease (SCD), a lifelong, devastating inherited blood disorder. The company has introduced Oxbryta® (voxelotor) tablets, the first FDA-approved treatment that directly inhibits sickle hemoglobin polymerization, the root cause of red blood cell sickling in SCD. GBT is also advancing its pipeline program in SCD with inclacumab, a P-selectin inhibitor in development to address pain crises associated with the disease, and GBT021601 (GBT601), the company’s next generation hemoglobin S polymerization inhibitor. In addition, GBT’s drug discovery teams are working on new targets to develop the next wave of treatments for SCD. To learn more, please visit www.gbt.com and follow the company on Twitter @GBT_news. Contact:Steven Immergut (media)650.410.3258simmergut@gbt.com Courtney Roberts (investors)650.351.7881croberts@gbt.com

  • Global Blood Therapeutics (GBT) Q4 2020 Earnings Call Transcript
    Motley Fool

    Global Blood Therapeutics (GBT) Q4 2020 Earnings Call Transcript

    GBT earnings call for the period ending December 31, 2020.