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Genocea Biosciences, Inc. (GNCA)

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2.5300-0.0600 (-2.32%)
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Previous Close2.5900
Open2.6100
Bid2.5000 x 900
Ask2.5900 x 900
Day's Range2.5200 - 2.6199
52 Week Range1.7400 - 5.7500
Volume62,274
Avg. Volume323,643
Market Cap137.72M
Beta (5Y Monthly)1.63
PE Ratio (TTM)N/A
EPS (TTM)N/A
Earnings DateN/A
Forward Dividend & YieldN/A (N/A)
Ex-Dividend DateN/A
1y Target EstN/A
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  • Genocea Presents Promising Long-term Results from GEN-009 Neoantigen Vaccine Phase 1 Trial at ASCO 2021
    GlobeNewswire

    Genocea Presents Promising Long-term Results from GEN-009 Neoantigen Vaccine Phase 1 Trial at ASCO 2021

    Four of nine checkpoint inhibitor-sensitive patients experienced RECIST responses post vaccination; median duration without disease progression after initial GEN-009 vaccination was 15 months Two of seven CPI-refractory patients experienced stable disease for up to 10 months after initial GEN-009 vaccination In the monotherapy cohort, six of eight patients with no measurable disease continue without recurrence for a median duration of 25 months after initial GEN-009 vaccination Augmented T cell

  • Genocea Provides First Quarter 2021 Corporate Update
    GlobeNewswire

    Genocea Provides First Quarter 2021 Corporate Update

    GEN-011 and GEN-009 immuno-oncology programs continue to advance Research on Inhibigens™ and SARS-CoV-2 continues to progress Conference call today at 8:30 a.m. E.T. CAMBRIDGE, Mass., April 29, 2021 (GLOBE NEWSWIRE) -- Genocea Biosciences, Inc. (NASDAQ: GNCA), a biopharmaceutical company developing next-generation neoantigen immunotherapies, today provided a business update for the first quarter ended March 31, 2021. “Genocea continues to accumulate evidence that our ATLAS™ platform may enable immunotherapies that preferentially attack the surface-presented antigens driving anti-tumor responses or as we say, ‘Targets Matter’,” said Chip Clark, Genocea’s President and Chief Executive Officer. “Whether through our ongoing clinical trials with GEN-011, our neoantigen-targeted peripheral T cell (“NPT”) therapy and GEN-009, our neoantigen vaccine, or through our research efforts with Inhibigens™ and SARS-CoV-2 antigen discovery, we look forward to providing updates consistent with this thesis throughout the year.” Clinical updatesGEN-011 Phase 1/2a clinical trial (the “TITAN study”) GEN-011 is in development to treat checkpoint inhibitor-refractory patients. Genocea believes using patient T cells taken from easily accessible peripheral blood and expanding the T cells only on tumor neoantigens prioritized by our ATLAS platform may give GEN-011 efficacy, accessibility and cost advantages over other T cell therapies. The TITAN study is designed to explore safety, biomarkers of activity and anti-tumor efficacy. During the first quarter, Genocea continued to add clinical sites and accrue patients. The company expects to have initial efficacy data from a patient subset late in the fourth quarter of 2021 or the first quarter of 2022. GEN-009 Phase 1/2a clinical trial The Company will provide long-term follow-up clinical and immunogenicity data from the ongoing Phase 1/2a clinical study at the American Society of Clinical Oncology (“ASCO”) 2021 Annual Meeting from June 4 - June 8. Research updatesInhibigens At the American Association for Cancer Research (“AACR”) Annual Meeting 2021 in April, the Company presented novel preclinical Inhibigen data highlighting that the presence of a single Inhibigen in an otherwise protective immunotherapy can completely reverse the therapy’s intended anti-tumor responses and the Inhibigen effect can be seen as early as 4 days post-dosing. SARS-CoV-2 The Company continues its SARS-CoV-2 research efforts to identify conserved antigens of protective T cell responses that may enable a next-generation vaccine protecting against a wide range of strains. Other business updatesStrengthened executive leadership team Genocea appointed Jacquelyn Sumer as Chief Legal and Compliance Officer. Jackie brings over fifteen years of legal experience, including roles at several biopharmaceutical companies with a focus in oncology and cell therapy experience development and commercialization. Financial and other updatesFirst quarter 2021 financial results Cash position: As of March 31, 2021, cash and cash equivalents were $66.0 million compared to $79.8 million as of December 31, 2020.Research and Development (R&D) expenses: R&D expenses were $8.8 million for the quarter ended March 31, 2021, compared to $10.0 million for the same period in 2020.General and Administrative (G&A) expenses: G&A expenses were $3.7 million for the quarter ended March 31, 2021, compared to $3.4 million for the same period in 2020.Net loss: Net loss was $12.0 million for the quarter ended March 31, 2021, compared to $12.9 million for the same period in 2020. Debt Refinancing In February 2021, the Company entered into an agreement with Silicon Valley Bank for a $10 million term loan. The proceeds from the loan were used to repay the Company’s outstanding loan from Hercules Capital, Inc., and for general corporate purposes. Guidance Genocea’s operating plan extends its cash runway to the end of 2022. Conference CallGenocea will host a conference call and webcast today at 8:30 a.m. E.T. Interested participants may access the conference call by dialing (844) 826-0619 (domestic) or (315) 625-6883 (international) and referring to conference ID number 2191366. To join the live webcast, please visit the presentation page of the investor relations section of the Genocea website at https://ir.genocea.com/events-presentations. A webcast replay of the conference call will be available on the Genocea website beginning approximately two hours after the event and will be archived for 90 days. About Genocea Biosciences, Inc.Genocea’s mission is to identify the right tumor targets to develop life-changing immunotherapies for people suffering from cancer. Our proprietary ATLAS™ platform comprehensively profiles each patient’s T cell responses to potential targets, or antigens, on that patient’s tumor. ATLAS zeroes in on both antigens that activate anti-tumor T cell responses and inhibitory antigens, InhibigensTM, that drive pro-tumor immune responses. We are advancing two ATLAS-enabled programs: GEN-009, our neoantigen vaccine for which we are conducting a Phase 1/2a clinical trial and GEN-011, our adoptive T cell therapy comprising neoantigen-targeted peripheral cells for which we are conducting a Phase 1/2a clinical trial. In addition to our two clinical programs, we are conducting research in several areas where we believe ATLAS could be a key tool in optimizing antigen selection for therapies across a number of diseases. To learn more, please visit https://www.genocea.com. Forward-Looking StatementsThis press release includes forward-looking statements related to GEN-009, GEN-011 and research updates within the meaning of the Private Securities Litigation Reform Act. Such forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied in such statements. Genocea cautions that these forward-looking statements are subject to numerous assumptions, risks and uncertainties that change over time. Applicable risks and uncertainties include those identified under the heading "Risk Factors" included in Genocea's Annual Report on Form 10-K for the year ended December 31, 2020 and any subsequent SEC filings. These forward-looking statements speak only as of the date of this press release and Genocea assumes no duty to update forward-looking statements, except as may be required by law. GENOCEA BIOSCIENCES, INC.CONDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED)(In thousands) March 31, 2021 December 31, 2020 Cash and cash equivalents $66,035 $79,769 Property and equipment, net 4,853 5,123 Right of use assets 8,831 9,308 Other assets 4,219 4,293 Total assets $83,938 $98,493 Accounts payable and accrued expenses $5,627 $7,878 Deferred revenue 1,641 1,641 Debt, current and long-term 9,649 13,862 Warrant liabilities 55,264 56,118 Lease liabilities 9,995 10,012 Total liabilities 82,176 89,511 Stockholders' equity 1,762 8,982 Total liabilities and stockholders’ equity $83,938 $98,493 GENOCEA BIOSCIENCES, INC.CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (UNAUDITED)(In thousands, except per share data) Three Months EndedMarch 31, 2021 2020Operating expenses: Research and development$8,751 $9,987 General and administrative3,671 3,388 Total operating expenses12,422 13,375 Loss from operations(12,422) (13,375)Other income439 522 Net loss$(11,983) $(12,853) Net loss per share: Basic$(0.18) $(0.46)Diluted$(0.17) $(0.46)Weighted-average number of shares used in computing net loss per share: Basic66,158 28,141 Diluted74,220 28,141 Investor Contact:Dan Ferry617-430-7576daniel@lifesciadvisors.com

  • ACCESSWIRE

    Genocea Biosciences, Inc. to Host Earnings Call

    NEW YORK, NY / ACCESSWIRE / April 29, 2021 / Genocea Biosciences, Inc. (NASDAQ:GNCA) will be discussing their earnings results in their 2021 First Quarter Earnings call to be held on April 29, 2021 at 8:30 AM Eastern Time.