GTHX - G1 Therapeutics, Inc.

NasdaqGS - NasdaqGS Real Time Price. Currency in USD
20.45
-1.09 (-5.06%)
As of 2:00PM EDT. Market open.
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Performance Outlook
  • Short Term
    2W - 6W
  • Mid Term
    6W - 9M
  • Long Term
    9M+
Previous Close21.54
Open21.81
Bid20.64 x 1000
Ask20.68 x 800
Day's Range20.25 - 22.18
52 Week Range8.80 - 41.80
Volume578,844
Avg. Volume519,846
Market Cap771.728M
Beta (5Y Monthly)2.27
PE Ratio (TTM)N/A
EPS (TTM)-3.45
Earnings DateMay 06, 2020
Forward Dividend & YieldN/A (N/A)
Ex-Dividend DateN/A
1y Target Est63.00
Fair Value is the appropriate price for the shares of a company, based on its earnings and growth rate also interpreted as when P/E Ratio = Growth Rate. Estimated return represents the projected annual return you might expect after purchasing shares in the company and holding them over the default time horizon of 5 years, based on the EPS growth rate that we have projected.
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  • Were Hedge Funds Right About Betting On G1 Therapeutics, Inc. (GTHX)?
    Insider Monkey

    Were Hedge Funds Right About Betting On G1 Therapeutics, Inc. (GTHX)?

    The latest 13F reporting period has come and gone, and Insider Monkey have plowed through 821 13F filings that hedge funds and well-known value investors are required to file by the SEC. The 13F filings show the funds' and investors' portfolio positions as of March 31st, a week after the market trough. Now, we are […]

  • GlobeNewswire

    G1 Therapeutics and Boehringer Ingelheim Announce Co-Promotion Agreement for Trilaciclib in Small Cell Lung Cancer in the United States and Puerto Rico

    G1 Therapeutics, Inc. (Nasdaq: GTHX) and Boehringer Ingelheim today announced that the companies have entered into a co-promotion agreement for trilaciclib in the United States and Puerto Rico. Under the terms of the three-year agreement, G1 and Boehringer Ingelheim will collaborate on the commercialization of trilaciclib for its first potential indication in small cell lung cancer (SCLC), with the Boehringer Ingelheim oncology commercial team, well-established in lung cancer, leading sales force engagement initiatives.

  • GlobeNewswire

    G1 Therapeutics and Genor Biopharma Announce Exclusive License Agreement for Lerociclib in Asia-Pacific Region

    G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, and Genor Biopharma Co. Inc., a pre-commercial stage biopharmaceutical company focused on developing and commercializing immune-oncology therapeutics, today announced an exclusive license agreement for the development and commercialization of lerociclib in the Asia-Pacific region (excluding Japan). Discovered and developed by G1, lerociclib is a differentiated oral CDK4/6 inhibitor designed to enable more effective combination treatment strategies.

  • Needham: 3 Conviction Buy Stocks to Snap up Now
    TipRanks

    Needham: 3 Conviction Buy Stocks to Snap up Now

    For investors feeling perplexed by the stock market’s roller coaster ride in 2020, you’re not alone. Following up a week that saw volatility make a comeback, stocks popped for the third session in a row on June 16, surging on a historic gain in retail sales and progress on a possible COVID-19 treatment. Rumors that the Trump administration is preparing a $1 trillion infrastructure bill also helped fuel the charge forward. That said, the rally came as investors brushed off reports of a cluster of new COVID-19 cases in the U.S. and China.Against this backdrop, finding investing inspiration can seem like a formidable task. The analysts from investment firm Needham, however, argue that even in such a confused financial environment, there are still compelling plays. Recently publishing its list of Conviction Buys, the firm, which scores a top ten spot on TipRanks’ ranking of Top Performing Research Firms, highlights several names it believes are set to outperform the broader market.To get the rest of the Street’s take, we ran three of Needham’s picks through TipRanks’ database. As it happens, the broader analyst community is also on board, with each ticker earning a “Strong Buy” consensus rating. Not to mention substantial upside potential is also on the table. Revance Therapeutics (RVNC)First up we have Revance Therapeutics, which is a biotech company that is primarily focused on aesthetic and therapeutic products, including its investigational neuromodulator asset, DaxibotulinumtoxinA for injection. After announcing a new partnership, Needham thinks the healthcare name’s future is bright.Representing the firm, analyst Serge Belanger cites its collaboration with Mylan as a key component of his bullish thesis. He reminds investors that the two companies first entered into a license agreement to develop a Botox biosimilar back in February 2018. This deal saw RVNC receive $25 million upfront, which was part of up to $100 million in regulatory and development milestones, with it eligible for up to $225 million in sales milestones and sales royalties.Now, Mylan has decided to move forward with the collaboration, with it set to pay RVNC $30 million in cash as part of the opt-in decision. “Mylan's opt-in decision, along with the $30 million payment, is a vote of confidence for the development plan and market opportunity of the Botox biosimilar program. The collaboration allows RVNC to focus on the upcoming product launches (Daxi and Teoxane fillers) and the continued development of Daxi, while MYL takes on an increasing role to move the Botox biosimilar program forward,” Belanger explained.As per the terms of the extended agreement, RVNC will be responsible for non-clinical development activities, clinical development for North America, the manufacturing and clinical supply of the drug, while Mylan will take on all ex-U.S. development and all commercialization activities. Approval, which could come via the 351(k) regulatory pathway, “would provide a biosimilar Botox product with access to the $3.6 billion Botox global market that includes all 13 FDA-approved Botox indications.” It should be noted that this product wouldn’t compete with Daxi, which will most likely “create a stand-alone long-acting premium neuromodulator market segment separate from current short-acting products”, in Belanger’s opinion. The analyst added, “This is another successful milestone in a catalyst-rich 2020 for RVNC.” These catalysts include the launch of the Teoxane filler in Q3 2020, readout of the Phase 3 Daxi trial in cervical dystonia and the November 25 PDUFA for Daxi (glabellar lines).In line with his bullish take, Belanger reiterated a Buy call and $36 price target. Should the target be met, a twelve-month gain of 58% could be in store. (To watch Belanger’s track record, click here)    Do other analysts agree with Bellanger? As it turns out, most do. 5 Buy ratings and a single Hold add up to a Strong Buy analyst consensus. At $28.20, the average price target indicates 23% upside potential. (See Revance stock analysis on TipRanks)G1 Therapeutics (GTHX)With a team that brings a deep understanding of the biology of cancer and extensive drug discovery, development and commercialization experience to the table, G1 Therapeutics wants to develop therapies for patients battling cancer. As the company has been able to progress on schedule despite COVID-19, Needham has been thoroughly impressed.5-star analyst Chad Messer tells clients that GTHX is still expected to file a trilaciclib (trila) NDA in Q2 2020 and an MAA in Q4 2020 for myelopreservation in small cell lung cancer (SCLC). This means that a PDUFA date would be handed out in Q3 2020. The analyst points out that the asset has already been given Breakthrough status by the FDA thanks to its ability to preserve the bone marrow of patients receiving marrow toxic chemotherapy.Expounding on this, Messer said, “The filing timing is unaffected by the COVID pandemic and the company has all the required data. G1 intends to market trila in the U.S. for SCLC by itself and seek an ex-U.S. partner while expanding the treatment into other tumor types and in combination with other chemotherapeutics.”Additionally, its Phase 3 program in CRC is moving right on track, and GTHX announced that trila would be included in the I-SPY trial for breast cancer, which should kick off this quarter.If that wasn’t enough, the monotherapy arm of the Phase 1/2 study evaluating rintodestrant is fully enrolled. “The ~40 patient combination expansion cohort (rintodestrant + palbociclib) will use the same sites and is expected to begin enrollment this quarter... Updated data from the monotherapy portion of the trial is expected Q3 2020,” Messer commented.With its $242 million cash runway set to support the company’s operations into Q4 2021, the deal is sealed for Messer. As a result, he left a Buy rating and $74 price target on the stock. This target suggests shares could soar 252% in the next year. (To watch Messer’s track record, click here)All in all, other analysts are on the same page. 3 Buys and no Holds or Sells add up to a Strong Buy consensus rating. Based on the $59.67 average price target, the upside potential comes in at 175%. (See GTHX stock analysis on TipRanks)NeoGenomics (NEO)As a cancer diagnostics and pharma services company, NeoGenomics offers diagnostic, prognostic and predictive testing services to oncologists, pathologists, pharmaceutical companies and academic centers. With it recently entering into a new strategic collaboration, Needham argues that NEO’s long-term growth narrative is strong.On May 26, NEO revealed that it would be partnering with Inivata to commercialize the InVisionFirst-Lung liquid biopsy test for treatment selection among non-small cell lung cancer (NSCLC) patients within the U.S. The product is a blood-based, next-generation sequencing (NGS) test that’s focused in NSCLC and performed on Inivata's patented liquid biopsy platform, InVision.Covering the stock for Needham, five-star analyst Stephen Unger points out that InVisionFirst-Lung has been given a final Medicare coverage decision, effective April 8, 2020, with the contract rate expected to land at $3,500 per test. Looking at the terms of the agreement, NEO will invest $25 million that will be paid in two installments of $12.5 million, with NEO also getting a seat on Inivata's board of directors. This equity investment puts NEO’s stake in Inivata at just under 20%.Along with the commercial rights, “NEO and Inivata will collaborate to advance the InVision liquid biopsy platform (i.e., Inivata's RaDaR assay for residual disease and recurrence monitoring) with pharmaceutical services customers.”Weighing in on this development, Unger noted, “We view the collaboration as a clear strategic positive for NEO, demonstrating the unique value of the company's commercial scale and national presence, which encompasses all aspects of cancer diagnostic testing. The InVisionFirst-Lung liquid biopsy test is complementary to NEO's NeoTYPE Cancer Profiles (NGS tests for solid tumors) and NeoLAB Heme (NGS liquid biopsy plasma-based tests for hematologic diseases).”As the companies are also expected to split the profits from tests performed evenly, Unger decided to stay with the bulls. To this end, he maintained a Buy rating and $33 price target. This target conveys his confidence in NEO’s ability to surge 16% in the next year. (To watch Unger’s track record, click here) Like Unger, other analysts also take a bullish approach. NEO’s Strong Buy consensus rating breaks down into 3 Buys and zero Holds or Sells. Given the $33.67 average price target, the upside potential lands just above Unger’s forecast at 19%. (See NeoGenomics stock-price forecast on TipRanks) To find good ideas for healhcare stocks trading at attractive valuations, visit TipRanks’ Best Stocks to Buy, a newly launched tool that unites all of TipRanks’ equity insights.

  • 2 Top Cancer Treatment Stocks to Buy in June
    Motley Fool

    2 Top Cancer Treatment Stocks to Buy in June

    Investors with extra cash on the sidelines may be able to capture some exciting cancer stocks at attractive prices. One company received approval from the Food and Drug Administration (FDA) for its cancer drug and is expanding to other indications. Another offers a promising pipeline with a strong patent portfolio that is in the process of regulatory submission.

  • How G1 Therapeutics (GTHX) Stock Stands Out in a Strong Industry
    Zacks

    How G1 Therapeutics (GTHX) Stock Stands Out in a Strong Industry

    G1 Therapeutics (GTHX) has seen solid earnings estimate revision activity over the past month, and belongs to a strong industry as well.

  • GlobeNewswire

    G1 Therapeutics Announces Flexible Credit Financing for Up to $100 Million with Hercules Capital

    G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, today announced that the company has entered into a debt financing agreement with Hercules Capital, Inc. (NYSE: HTGC) for up to $100 million. G1 plans to use the proceeds to fund commercialization and further development of trilaciclib, its first-in-class investigational therapy designed to improve outcomes for people with cancer treated with chemotherapy.

  • GlobeNewswire

    G1 Therapeutics to Present Data Showing Myelopreservation Benefits of Trilaciclib in Patients with Small Cell Lung Cancer at the ASCO20 Virtual Scientific Program

    - Trilaciclib significantly reduced myelosuppression and need for related supportive care interventions for patients with small cell lung cancer (SCLC) receiving chemotherapy -.

  • G1 Therapeutics, Inc. (GTHX) Q1 2020 Earnings Call Transcript
    Motley Fool

    G1 Therapeutics, Inc. (GTHX) Q1 2020 Earnings Call Transcript

    On today's call, Mark Velleca, Chief Executive Officer; Raj Malik, Chief Medical Officer and Senior Vice President of R&D and Jen Moses, Chief Financial Officer will provide an overview of the quarter with Q&A to follow. Before we begin, I would like to remind you that this call will include forward-looking statements based on current expectations.

  • GlobeNewswire

    G1 Therapeutics Provides First Quarter 2020 Corporate and Financial Update

    G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, today provided a corporate and financial update for the first quarter ended March 31, 2020. “We have activated business continuity plans in response to the COVID-19 pandemic to ensure we can advance therapies that patients with cancer, their families, and healthcare providers are counting on to improve outcomes, and also taken actions to safeguard the well-being of our employees,” said Mark Velleca, M.D., Ph.D., Chief Executive Officer.

  • We Think G1 Therapeutics (NASDAQ:GTHX) Can Afford To Drive Business Growth
    Simply Wall St.

    We Think G1 Therapeutics (NASDAQ:GTHX) Can Afford To Drive Business Growth

    Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...

  • GlobeNewswire

    G1 Therapeutics to Provide First Quarter 2020 Corporate and Financial Update on May 6, 2020

    RESEARCH TRIANGLE PARK, N.C., April 29, 2020 -- G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, today announced that it will host a webcast and.

  • GlobeNewswire

    G1 Therapeutics to Present at 19th Annual Needham Virtual Healthcare Conference on April 14, 2020

    RESEARCH TRIANGLE PARK, N.C., April 07, 2020 -- G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, today announced that Chief Executive Officer Mark.

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    There's a growing consensus that the Triangle is not only strapped for the venture capital needed to make innovative ideas coming out of local universities work, but it is also severely lacking in the kind of corporate leadership needed to guide innovation to successful commercial companies.

  • GlobeNewswire

    G1 Therapeutics Announces Appointment of New Board Member and Chief Commercial Officer

    G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, today announced the appointments of Jack Bailey to its Board of Directors and Soma Gupta as its Chief Commercial Officer (CCO). “We are pleased to welcome Jack and Soma, and their breadth of commercial experience, as we work toward the approval of trilaciclib in small cell lung cancer,” said Mark Velleca, M.D., Ph.D., Chief Executive Officer.

  • GlobeNewswire

    G1 Therapeutics Provides Fourth Quarter and Full-Year 2019 Corporate and Financial Update

    New Drug Application (NDA) submission for trilaciclib in small cell lung cancer on track for 2Q20Trilaciclib selected for inclusion in I-SPY 2 breast cancer trialRintodestrant.

  • Advance Auto Parts, Cree among Triangle companies hit as stocks tumble with rising concern over coronavirus
    American City Business Journals

    Advance Auto Parts, Cree among Triangle companies hit as stocks tumble with rising concern over coronavirus

    Global concerns over the spread of the novel coronavirus rocked stock markets on Monday. The spread of COVID-19 has been a major economic punch felt around the globe, and it's impacting production at Triangle firms – from Lenovo to Cree.

  • GlobeNewswire

    G1 Therapeutics to Present at Investor Conferences in March 2020

    RESEARCH TRIANGLE PARK, N.C., Feb. 24, 2020 -- G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, today announced that the company will present corporate.

  • GlobeNewswire

    G1 Therapeutics to Provide Fourth Quarter and Full Year 2019 Corporate and Financial Update on February 26, 2020

    RESEARCH TRIANGLE PARK, N.C., Feb. 19, 2020 -- G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, today announced that it will host a webcast and.

  • GlobeNewswire

    G1 Therapeutics to Participate in BTIG Targeted Therapeutics Conference on February 24, 2020

    RESEARCH TRIANGLE PARK, N.C., Feb. 18, 2020 -- G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, today announced that Chief Medical Officer Raj Malik,.

  • GlobeNewswire

    G1 Therapeutics to Participate in Guggenheim Health Talks: Oncology Day on February 13, 2020

    RESEARCH TRIANGLE PARK, N.C., Feb. 06, 2020 -- G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, today announced that Chief Executive Officer Mark.

  • Quantum Leap Healthcare Collaborative and G1 Therapeutics Announce the Selection of Trilaciclib in the I-SPY 2 TRIAL for Breast Cancer
    PR Newswire

    Quantum Leap Healthcare Collaborative and G1 Therapeutics Announce the Selection of Trilaciclib in the I-SPY 2 TRIAL for Breast Cancer

    Quantum Leap Healthcare Collaborative™ and G1 Therapeutics, Inc. (Nasdaq: GTHX) announced today a collaboration to evaluate trilaciclib, an investigational therapy designed to improve outcomes for people with cancer treated with chemotherapy, in a new randomized, investigational treatment arm for the ongoing I-SPY 2 TRIAL™ for neoadjuvant treatment of locally advanced breast cancer.

  • GlobeNewswire

    G1 Therapeutics to Present at 38th Annual J.P. Morgan Healthcare Conference

    RESEARCH TRIANGLE PARK, N.C., Jan. 07, 2020 -- G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, today announced that Chief Executive Officer Mark.

  • GlobeNewswire

    G1 Therapeutics Presents Updated Data from Phase 1b/2a Trial of Oral CDK4/6 Inhibitor Lerociclib at 2019 San Antonio Breast Cancer Symposium (SABCS)

    G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, today reported additional data from the Phase 1b/2a clinical trial investigating its oral CDK4/6 inhibitor lerociclib in combination with fulvestrant for the treatment of estrogen receptor-positive, HER2-negative (ER+, HER2-) breast cancer. Updated findings presented during a poster session (P1-19-17) at the 2019 San Antonio Breast Cancer Symposium (SABCS) showed lerociclib, dosed without a drug holiday, has a differentiated safety and tolerability profile than observed in clinical trials with currently marketed CDK4/6 inhibitors.

  • GlobeNewswire

    G1 Therapeutics to Participate in Evercore ISI 2nd Annual HealthCONx Conference on December 4, 2019

    RESEARCH TRIANGLE PARK, N.C., Nov. 26, 2019 -- G1 Therapeutics, Inc. (Nasdaq: GTHX), a clinical-stage oncology company, today announced that Chief Executive Officer Mark.