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Kaleido Biosciences, Inc. (KLDO)

NasdaqGS - NasdaqGS Delayed Price. Currency in USD
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7.71+0.27 (+3.63%)
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Previous Close7.44
Open7.47
Bid7.47 x 1100
Ask7.79 x 1000
Day's Range7.47 - 7.71
52 Week Range2.82 - 10.00
Volume2,785
Avg. Volume175,945
Market Cap274.064M
Beta (5Y Monthly)N/A
PE Ratio (TTM)N/A
EPS (TTM)-2.62
Earnings DateOct 28, 2020 - Nov 02, 2020
Forward Dividend & YieldN/A (N/A)
Ex-Dividend DateN/A
1y Target Est13.00
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  • GlobeNewswire

    Kaleido Biosciences to Present at the Canaccord Genuity 40th Annual Growth Conference

    LEXINGTON, Mass., Aug. 05, 2020 (GLOBE NEWSWIRE) -- Kaleido Biosciences, Inc. (Nasdaq: KLDO), a clinical-stage healthcare company with a chemistry-driven approach to targeting the microbiome to treat disease and improve human health, today announced that Michael Bonney, Executive Chair, will participate in a fireside chat at the virtual Canaccord Genuity 40th Annual Growth Conference on Thursday, August 13, 2020 at 3:30 p.m. ET. A live webcast will be available in the Investors & Media section of Kaleido’s website at https://investors.kaleido.com/events-presentations. An archived replay will be accessible for 90 days following the event.About Kaleido Biosciences Kaleido Biosciences is a clinical-stage healthcare company with a differentiated, chemistry-driven approach to targeting the microbiome to treat disease and improve human health. The Company has built a proprietary product platform to enable the rapid and cost-efficient discovery and development of novel Microbiome Metabolic Therapies (MMT™). MMTs are designed to modulate the metabolic output and profile of the microbiome by driving the function and distribution of the gut’s existing microbes. Kaleido is advancing a broad pipeline of MMT candidates with the potential to address a variety of diseases and conditions with significant unmet patient needs. To learn more, visit https://kaleido.com/.ContactsKaleido Biosciences William Duke, Jr. Chief Financial Officer 617-890-5772 william.duke@kaleido.comInvestorsLee M. Stern Solebury Trout 646-378-2922 lstern@soleburytrout.comMediaJoshua R. Mansbach Solebury Trout 646-378-2964  jmansbach@troutgroup.com

  • GlobeNewswire

    Kaleido Biosciences Reports Second Quarter 2020 Financial Results and Provides Corporate Update

    \- COVID-19 Clinical Development Program Topline Data Readout of Multi-Center Study Expected in Q4 2020 - \- Plan to Initiate New Clinical Study in Ulcerative Colitis in Q3 2020 - LEXINGTON, Mass., Aug. 04, 2020 (GLOBE NEWSWIRE) -- Kaleido Biosciences, Inc. (Nasdaq: KLDO), a clinical-stage healthcare company with a chemistry-driven approach to targeting the microbiome to treat disease and improve human health, today announced financial results for the second quarter 2020 and provided a corporate update. “We have made several important advancements across critical areas of the business, including initiating two clinical studies in our COVID-19 program and strengthening our financial foundation by extending our cash runway into the second half of 2021,” said Michael Bonney, Executive Chair of Kaleido. “We anticipate top-line data from the 350-patient, multi-center COVID-19 study in the fourth quarter. We also continue to make progress on our preclinical programs and look forward to reporting data in the fourth quarter from our immuno-oncology, cardiometabolic and liver disease programs.” Company Highlights * Initiated two non-IND clinical studies that are part of the ongoing COVID-19 clinical development program evaluating KB109 when added to Supportive Self-Care in outpatients with mild-to-moderate COVID-19 disease: clinical study K031 is a multi-center study of approximately 350 patients and clinical study K032, in collaboration with Massachusetts General Hospital, aims to include approximately 50 patients.   * Completed a $35.6 million offering of common stock.Anticipated Milestones * Clinical and ex vivo data from KB174, being developed for the treatment of hepatic encephalopathy (HE), to be featured in poster presentations during The Digital International Liver Congress™ (EASL 2020) August 27-29, 2020.   * Topline data from the multi-center (K031) clinical study of KB109 in patients with mild-to-moderate COVID-19 disease expected in Q4 2020 and top-line data from the study with Massachusetts General Hospital (K032) are expected in the first quarter of 2021. A patient may be enrolled in the study if an initial positive COVID-19 test result is received and the patient remains symptomatic.   * Initiating a clinical study in Q3 2020 evaluating KB295 in approximately 30 patients with mild-to-moderate ulcerative colitis (UC). Topline results are expected in mid-2021.   * Preclinical data from the immuno-oncology, cardiometabolic and liver diseases programs expected in Q4 2020.   * Topline data from Phase 2 clinical trial (UNLOCKED) of KB195 in patients with UCD inadequately controlled on standard of care in second half 2021.Second Quarter 2020 Financial ResultsFor the second quarter 2020, Kaleido reported a net loss of $18.9 million, or $0.59 per common share, compared to $24.6 million, or $0.83 per common share, for the second quarter 2019. The 2020 second quarter net loss includes non-cash stock-based compensation expenses of $2.8 million, as compared to $2.4 million in the second quarter of 2019.Research and development (R&D) expenses were $12.8 million for the second quarter 2020, compared to $18.8 million for the second quarter 2019. The second quarter decrease in R&D, as compared to the second quarter of 2019, was primarily driven by decreased external development, manufacturing, and research costs.General and administrative (G&A) expenses were $5.6 million for the second quarter 2020, compared to $6.2 million for the second quarter of 2019. The second quarter 2020 decrease in G&A, as compared to the second quarter of 2019, was primarily due to decreased personnel-related costs, partially offset by increased facility-related expenses.As of June 30, 2020, the Company reported cash and cash equivalents of $71.0 million and has cash runway into the second half of 2021.About Microbiome Metabolic Therapies (MMT™)Kaleido’s Microbiome Metabolic Therapies, or MMTs, are designed to drive the function and distribution of the microbiome’s existing microbes in order to decrease or increase the production of metabolites, or to advantage or disadvantage certain bacteria in the microbiome community. The Company’s initial MMT candidates are targeted, synthetic glycans that are orally administered, have limited systemic exposure, and are selectively metabolized by enzymes in the microbiome. Kaleido utilizes its discovery and development platform to study MMTs in microbiome samples to rapidly advance MMT candidates rapidly into clinical studies in healthy subjects and patients. These human clinical studies are conducted under regulations supporting research with food, evaluating safety, tolerability and potential markers of effect. For MMT candidates that are further developed as therapeutics, the Company conducts clinical trials under an Investigational New Drug (IND) or regulatory equivalent outside the U.S., and in Phase 2 or later development.   About Kaleido BiosciencesKaleido Biosciences is a clinical-stage healthcare company with a differentiated, chemistry-driven approach to targeting the microbiome to treat disease and improve human health. The Company has built a proprietary product platform to enable the rapid and cost-efficient discovery and development of novel Microbiome Metabolic Therapies (MMT™). MMTs are designed to modulate the metabolic output and profile of the microbiome by driving the function and distribution of the gut’s existing microbes. Kaleido is advancing a broad pipeline of MMT candidates with the potential to address a variety of diseases and conditions with significant unmet patient needs. To learn more, visit https://kaleido.com/.Forward-Looking StatementsThis press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, without limitation, statements regarding the therapeutic potential of our MMT candidates, the timing of initiation, completion and reporting of results of our clinical and preclinical studies, our anticipated cash runway and our strategy, business plans and focus. The words “may,” “will,” “could,” “would,” “should,” “expect,” “plan,” “anticipate,” “intend,” “believe,” “estimate,” “predict,” “project,” “potential,” “continue,” “target” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements in this press release are based on management’s current expectations and beliefs and are subject to a number of risks, uncertainties and important factors that may cause actual events or results to differ materially from those expressed or implied by any forward-looking statements contained in this press release, including, without limitation, those related to the breadth of our pipeline of product candidates, the strength of our proprietary product platform, the efficiency of our discovery and development approach, the clinical development and safety profile of our MMT candidates and their therapeutic potential, whether and when, if at all, our MMT candidates will receive approval form the U.S. Food and Drug Administration and for which, if any, indications, competition from other biotechnology companies, and other risks identified in our SEC filings, including our most recent Form 10-K, and subsequent filings with the SEC. We caution you not to place undue reliance on any forward-looking statements, which speak only as of the date they are made. We disclaim any obligation to publicly update or revise any such statements to reflect any change in expectations or in events, conditions or circumstances on which any such statements may be based, or that may affect the likelihood that actual results will differ from those set forth in the forward-looking statements. Kaleido Biosciences, Inc. and Subsidiaries  Condensed Consolidated Statement of Operations (Unaudited)  (in thousands, except share and per share data)                  Three Months Ended June 30, Six Months Ended June 30,      2020 2019   2020  2019  Income:             Collaboration revenue $  250  $   —  $250  $ —  Operating expenses:                 Research and development  12,833   18,775   25,970   33,957    General and administrative  5,559   6,181  11,476  11,614    Total operating expenses  18,392   24,956  37,446  45,571  Loss from Operations    (18,142)  (24,956) (37,196)  (45,471)   Other (expense) income, net  (780)  317   (1,277) 713  Net loss $  (18,922) $(24,639) $(38,473)  $(44,858) Net loss per share — basic and diluted $(0.59) $(0.83) $(1.24)  $(2.10) Weighted-average common shares outstanding — basic and diluted  31,880,672   29,667,221  31,106,977    21,361,749  Kaleido Biosciences, Inc. and Subsidiaries Condensed Consolidated Balance Sheet Data (Unaudited) (in thousands)           June 30, 2020 December 31, 2019 Assets:      Cash and cash equivalents $71,032  $71,241   Other assets  15,947   11,065   Total assets $  86,979  $82,306  Liabilities and stockholders' equity      Liabilities $35,657  $33,423   Stockholders' equity  51,322   48,883  Total liabilities and stockholders' equity $86,979  $82,306  ContactsKaleido Biosciences William Duke, Jr. Chief Financial Officer 617-890-5772 william.duke@kaleido.com InvestorsLee M. Stern Solebury Trout 646-378-2922 lstern@soleburytrout.comMediaJoshua R. Mansbach Solebury Trout 646-378-2964 jmansbach@troutgroup.com