|Bid||0.00 x 2200|
|Ask||0.00 x 1100|
|Day's Range||9.75 - 10.24|
|52 Week Range||9.10 - 16.99|
|Beta (5Y Monthly)||N/A|
|PE Ratio (TTM)||N/A|
|Forward Dividend & Yield||N/A (N/A)|
|1y Target Est||N/A|
The FDA has signed off Landos Biopharma's (NASDAQ: LABP) Investigational New Drug application for omilancor (BT-11) for the treatment of Eosinophilic Esophagitis (EoE). Landos expects to initiate patient dosing in the first half of 2022. The 36-subject Phase 1b study is designed to evaluate the safety and pharmacokinetics of omilancor. Patients will be randomized in a 1:1:1 ratio to receive either omilancor 500 mg twice daily, omilancor 1000 mg once daily, or placebo for 12 weeks. Each of the treatment arms will include 12 subjects. The primary safety endpoint will measure the frequency and severity of adverse events and changes in clinical chemistry and hematology from baseline. The secondary endpoint is a pharmacokinetic analysis of omilancor plasma levels at various time intervals post-dosing, in addition to evaluating the mean concentration of omilancor in esophageal biopsy tissue after 12 weeks of dosing. Omilancor is an orally active, gut-restricted small molecule investigational drug that targets the Lanthionine Synthetase C-like 2 pathway impacting the gastrointestinal tract. LANCL2 plays a vital role in the immunoregulatory process. The Company reported initial Phase 2 results of omilancor evaluating patients with ulcerative colitis in 2021 and expects to initiate a Phase 3 trial in the second half of 2021. Additionally, Landos plans to initiate a Phase 2 trial of omilancor in patients with Crohn's disease in the first half of this year. Price Action: LABP shares are trading 6.4% higher at $9.85 on the last check Tuesday. See more from BenzingaClick here for options trades from BenzingaIonis Antisense Oligonucleotides To Be Evaluated With Progenity's Drug Delivery SystemAzurRx BioPharma To Test Formulated Niclosamide In COVID-19-Related Gastrointestinal Infections© 2021 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.
Icahn Capital reached a pact to appoint Bausch Health directors. Perceptive Advisors disclosed a large stake in Landos Biopharma.
A flock of biotech companies are opening for trading Friday. Most of the deals grew in size, with price increases as well. Vor Biopharma stock rocketed at its open.