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Major Holders

Currency in USD
Breakdown
0.89%Shares Held by All Insider and 5% Owners
98.10%% of Shares Held by Institutional & Mutual Fund Owners
98.98%% of Float Held by Institutional & Mutual Fund Owners
220Number of Institutions Holding Shares
Direct Holders (Forms 3 and 4)
NameSharesDate Reported
GORMAN KEVIN CHARLES332,607May 1, 2017
LYONS GARY A282,066Feb 13, 2017
COUGHLIN TIMOTHY P137,961Feb 5, 2017
BOZIGIAN HAIG P.129,601Aug 3, 2017
GRIGORIADIS DIMITRI E.107,691Aug 8, 2017
GANO KYLE73,246Apr 30, 2017
MOLLICA JOSEPH A56,042Apr 11, 2017
OBRIEN CHRISTOPHER FLINT48,973Jul 26, 2017
SHERWIN STEPHEN A43,879Feb 6, 2017
NEVINNY CORINNE H34,603May 4, 2017

Top Institutional Holders

HolderSharesDate Reported% OutValue
FMR, LLC13,211,023Jun 29, 201715.00%601,894,226
Price (T.Rowe) Associates Inc7,165,884Jun 29, 20178.14%326,477,684
Vanguard Group, Inc. (The)6,922,294Jun 29, 20177.86%315,379,724
Janus Henderson Group PLC5,367,124Jun 29, 20176.09%244,526,176
Blackrock Inc.4,802,227Jun 29, 20175.45%218,789,468
Perceptive Advisors LLC3,577,589Jun 29, 20174.06%162,994,959
BB Biotech Ag3,446,552Jun 29, 20173.91%157,024,913
Franklin Resources, Inc3,378,615Jun 29, 20173.84%153,929,704
Wellington Management Company, LLP3,028,916Jun 29, 20173.44%137,997,417
Invesco Ltd.2,956,588Jun 29, 20173.36%134,702,153

Top Mutual Fund Holders

HolderSharesDate Reported% OutValue
Fidelity Contrafund Inc3,113,806May 30, 20173.54%135,512,838
Fidelity Select Portfolios - Biotechnology2,646,151May 30, 20173.00%115,160,492
Vanguard Small-Cap Index Fund1,939,904Dec 30, 20162.20%73,696,956
Vanguard Total Stock Market Index Fund1,853,149Dec 30, 20162.10%70,401,133
Janus Henderson Enterprise Fund1,689,313Mar 30, 20171.92%70,342,992
Price (T.Rowe) Health Sciences Fund1,648,228Mar 30, 20171.87%68,632,212
SPDR (R) Ser Tr-SPDR (R) S&P (R) Biotech ETF1,452,522May 30, 20171.65%63,213,758
Hartford Mid Cap Fund1,258,150Apr 29, 20171.43%67,424,258
iShares NASDAQ Biotechnology ETF1,120,133May 30, 20171.27%48,748,188
Vanguard Small-Cap Growth Index Fund1,081,575Dec 30, 20161.23%41,089,036