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Novartis AG (NVS)

NYSE - NYSE Delayed Price. Currency in USD
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85.91+0.77 (+0.90%)
At close: 04:00PM EST
85.99 +0.08 (+0.09%)
After hours: 06:27PM EST
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  • a
    arthur
    make a hostile take over the shareholders are ready and willing !
  • D
    Drwho

    DR RNAi (Harvard, MIT)
    @fpscod9
    ·
    12h

    Replying to
    @truthtracer
    and
    @BikeRieder
    2022-2023
    $NVS takes out $ALNY
    2023-2024
    $JNJ takes out $ARWR
  • n
    nancys
    Does anyone have any numbers on the expected sales of Leqvio-Incliserin for 2022, here in the US with approval and in Europe where it has been available?
    A lot of people cannot tolerate statins, and this is a better than antibody side effect profile alternative.
  • N
    Novice
    Question for US investors:
    If the shares are held in a taxable account, is there a withholding tax on the dividend?
  • s
    samuelrobi
    $NVS will stick to the same business development strategy - a focus on smaller, "bolt-on" deals - despite the substantial $20bn cash influx from the sale of its stake in Roche, management said during an R&D day. No interest in large M&A.
  • A
    Anonymous
    Both Pfizer and Novartis are good to buy, than QQQ now. Novartis is a better buy due to its valuation.
  • A
    Anonymous
    Time for NVS to start using the $15B to buy stock at these low levels!
  • L
    Luis
    Investing right now will be at every wise individual list. In few weeks you'll be ecstatic with the decision you made today
  • d
    dougie
    DJ Novartis to Buy Back Up to $15 Bln of Its Shares
  • a
    arthur
    Come on NVS with that money from Roche buy Aurina ! They had great news yesterday on their lupus drug safety over a three year period.
  • T
    Thirdmeinvestor
    $VRTX conversation
    Investors in $NVS demand company do something with cash position (=$20+B). According to Bloomberg. Novartis could acquire $ALNY, but Alnylam does not generate cash as Vertex does.
  • W
    William
    Any rumors here about Novartis buying out GERN
  • t
    tom
    Looks like Novartis will owe 9 figures in royalties to RGNX for a very long time with approval of Zolgensma.At 1.7 billion market cap of RGNX with its 450 million in cash and 0 debt, it would be much cheaper to buy RGNX as it also owns a 100 AAV gene library which has a private market value of $6 billion USD
  • C
    Conroy
    Biggest winner is the babies. Then biggest winner is RGNX = Regenex bio which gets 9-13 % royalties on Zolgensma which makes it 9 figures on royalties or $6-7 eps in 24 months. AT RGNX $48 it has $450 million in cach and 0 debt and sells at book value. It owns the $6 billion private market value 100 AAV gene platform which is used by every gene therapy drug to make it work as a gene vector. RGNX worth over $155+ a share and is involved in ALS= Lou Gehrigs disease and Rett syndrome and SMA type 1 and Sma type 2 with Novartis.
  • T
    Timothy
    The stock will climb into the 90's next week. I will add on to my position on Tuesday. Very impressive week for NVS. Deep pipeline makes NVS a stock with a lot price appreciation for years to come.
  • S
    Steven
    Market Cap.

    Look at Novartis...a true global big pharma. Market cap $200b.

    Heart disease. Oncology. All kinds of products sold in every global market.

    People who think NVAX can be $90b are smoking krak.

    $25b at the top end. 2022, firing on all cylinders.
  • t
    technicals13
    FDA Accepts AveXis’ BLA for SMA Drug Zolgensma Under Priority Review
    MDA STAFF 12/03/2018
    Today, Novartis, the parent company of AveXis Inc., announced that the U.S. Food and Drug Administration (FDA) has accepted the company’s Biologics License Application (BLA) under Priority Review for Zolgensma (formerly known as AVXS-101), a gene therapy for the treatment of spinal muscular atrophy (SMA) type 1. Priority Review status requires the FDA to review the application and make a decision on whether to approve Zolgensma within six months (the typical review period is 10 months). An anticipated decision is expected in May 2019.

    Zolgensma is a gene therapy that targets the root cause of SMA by delivering a gene to replace the missing or mutated survival of the motor neuron 1 (SMN1) gene. The therapy is a one-time infusion. SMA is a genetic disease affecting the part of the nervous system that controls voluntary muscle movement. Infants with SMA type 1 typically do not survive more than two years.

    Treatment with the therapy in a Phase 1 clinical trial was associated with an increased survival rate compared to the normal course of the disease and the achievement and maintenance of motor milestones that infants with SMA type 1 normally would not be expected to achieve. In the START trial, all 15 patients infused with Zolgensma — three with low dose, 12 with high dose — were alive and event-free at 24 months, compared to 8 percent in a natural history study. An “event” was defined as either death, or at least 16 hours per day of required ventilation support for breathing for 14 consecutive days in the absence of acute reversible illness or surgery. At 24 months, 11 of the 12 high-dose patients could keep their head erect for more than three seconds and sit without support for more than five seconds, 10 patients were able to sit without support for more than 10 seconds, 9 patients were able to sit without support for more than 30 seconds and two patients were able to stand and walk alone without assistance.

    The trial also showed meaningful respiratory results. Of the 10 patients who were not using non-invasive ventilation (NIV) at the start of the trial, seven of them remained NIV-free after 24 months. More importantly, all patients, whether ventilated or not, survived respiratory hospitalizations without tracheostomy or permanent ventilation.

    The most commonly observed side effect of Zolgensma was elevated liver enzymes.

    This announcement underscores the importance of newborn screening to diagnose SMA before babies are symptomatic so they can be treated as early as possible. With the news earlier in the year of SMA being added to the national Recommended Uniform Screening Panel (RUSP), this latest announcement makes it even more important for states to add SMA to their respective newborn screening panels to find babies who may benefit from approved therapies or be eligible to participate in clinical trials.

    Zolgensma is currently in Phase 3 clinical trials for SMA type 1 and is also being tested in a Phase 1 trial for SMA type 2. Additionally, Zolgensma is being tested in a Phase 3 trial for pre-symptomatic newborns diagnosed with SMA types 1, 2 and 3.

    For information regarding eligibility criteria for currently enrolling or planned clinical trials, view the listings on www.ClinicalTrials.gov or www.studysmanow.com, or contact medinfo@avexis.com.

    For more information regarding Zolgensma, check back at mda.org.

    Click here to read the press release from AveXis.
    Home - ClinicalTrials.gov
    www.ClinicalTrials.gov
  • A
    AIKIDO
    $AMRN , JT presentation today is super strong BP wake up and buyout this company even at $50B looks cheap going forward $PFE $AMGN. $NVS. $GSK spend the money it’s worth it, ADA Standard of Care , Diabetes community is a very lucrative big market 90 million of them according to JT , wow that alone counts in BILLIONS, JT always says we’re not competing in Statins $500B markets but Triglycerides and Cholesterol is entangled now that will take many BILLIONS from that, Atherosclerosis, Alzheimer’s and Cancers future collaborators are looking at that too, AMRN is severely undervalued here and should be close to $100/Shares, A game changer just like $BYND and $UBER in each industry
    Bullish
  • a
    andrew
    Calling all Novartis insiders/employees .... any truth to the statement... "Gerons banking info has been added to the NOVARTIS financial system?" thanks for your input.
  • A
    AIKIDO
    Imagine Pfizer sales force selling Vascepa’s right now the $2B to $4B sales easily achieved (above 500 Triglycerides) some off label use too, Now the sNDA as we know it is 20X bigger (150 to 500) US alone, new report is China’s 185M People have very high Triglycerides, this one is massive going forward, $NVS or $PFE will have epic buyout
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