| 6.44% | % of Shares Held by All Insider |
| 103.03% | % of Shares Held by Institutions |
| 110.12% | % of Float Held by Institutions |
| 254 | Number of Institutions Holding Shares |
| Holder | Shares | Date Reported | % Out | Value |
|---|---|---|---|---|
| Wellington Management Company, LLP | 5,996,082 | Dec 30, 2018 | 11.95% | 260,709,645 |
| Capital Research Global Investors | 5,856,155 | Dec 30, 2018 | 11.67% | 254,625,619 |
| Capital International Investors | 4,589,854 | Dec 30, 2018 | 9.15% | 199,566,851 |
| Blackrock Inc. | 4,476,812 | Dec 30, 2018 | 8.92% | 194,651,785 |
| Vanguard Group, Inc. (The) | 4,161,780 | Dec 30, 2018 | 8.29% | 180,954,194 |
| FMR, LLC | 2,946,924 | Dec 30, 2018 | 5.87% | 128,132,255 |
| Price (T.Rowe) Associates Inc | 2,730,381 | Dec 30, 2018 | 5.44% | 118,716,965 |
| State Street Corporation | 2,051,639 | Dec 30, 2018 | 4.09% | 89,205,263 |
| Capital World Investors | 1,583,390 | Dec 30, 2018 | 3.16% | 68,845,797 |
| First Trust Advisors LP | 1,471,934 | Dec 30, 2018 | 2.93% | 63,999,690 |
| Holder | Shares | Date Reported | % Out | Value |
|---|---|---|---|---|
| Growth Fund Of America Inc | 4,322,964 | Sep 29, 2018 | 8.61% | 330,015,071 |
| New Perspective Fund Inc | 2,768,288 | Sep 29, 2018 | 5.52% | 211,331,105 |
| Smallcap World Fund | 1,964,870 | Sep 29, 2018 | 3.92% | 149,998,175 |
| Hartford Mid Cap Fund | 1,604,618 | Jul 30, 2018 | 3.20% | 126,941,329 |
| Fidelity Select Portfolios - Biotechnology | 1,433,037 | Nov 29, 2018 | 2.86% | 76,911,095 |
| Vanguard Total Stock Market Index Fund | 1,165,323 | Sep 29, 2018 | 2.32% | 88,960,757 |
| Vanguard Small-Cap Index Fund | 1,154,011 | Sep 29, 2018 | 2.30% | 88,097,199 |
| New Economy Fund (The) | 1,152,106 | Sep 29, 2018 | 2.30% | 87,951,772 |
| iShares Russell 2000 ETF | 1,052,521 | Nov 29, 2018 | 2.10% | 56,488,802 |
| Federated Kaufmann Fund | 989,334 | Sep 29, 2018 | 1.97% | 75,525,757 |