Summit Therapeutics Inc. (SMMT)

Nearly all Sarepta followers saw this coming.
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$SMMT Ezutromid Development to be Discontinued.Bio Stocks™ added,

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https://www.tradingview.com/chart/RMANF/aVxRVylL-RMANF-New-Cannabis-Alternative-Jumps-21-during-Mondays-session/

Here's a quick resume for NEW READERS! In terms of SMMT investment. What's clear - right here - right now, is that if you had $100 to invest today, Summit's current market cap of $220 million may well be worth $2 billion by end of year. ie if EZD 48 wk trials (results due July / Aug) simply follow on from 24 wk data (see results published in January) and EZD is taken to FDA who will likely approve it on qMR "endpoint" info alone, (See latest FDA approval terms for endorsement - MRI and biomarker info is now endpoint of choice) ... one can assume that the drug value would likely be $2 billion. I base this conservative figure on a company like Sarepta with a fix for only 13% DMD boys achieving mkt cap $5 Billion. Summit has a fix intended for 100% boys. However Summit have valued their treatment on the market at being around $100,000 per boy, per year as opposed to for example Sarepta who are currently charging $300,000 per boy per year. $2 billion is therefore a conservative comparison IMO.

If this drug is then made available for 100% of DMD boys and mrkt cap is say $2 billion ... investment of $100 would be X 10 by year end = $1000.

IMO the only risk folk are taking here is the very remote possibility that EZD 24 wk data was some fluke. (So there is a small risk still attached) We know the trial has been completed and NO safety issues. Just slight improvement in figures (continued build up off drug most likely to show improvement) will most likely result in a pass for qMR endpoint and in response the 6MWT and ambulatory functions will show actual positive effect. (Though as in Sarepta's case this was only shown to be tiny improvement at end of P2 ... not IMO relying on those figures which have historically been hard to show elsewhere)

We also know that this drug will in principle help Becker MD sufferers ... that's the same number of sufferers again. Summit will also carry on increasing in value as C Diff and Gonorrhea drugs complete trials. C Diff has already passed P2 and shown to be very best in class .... keeping thousands of people alive who simply go into hospitals and pick up C Diff whilst undergoing routine operations. C Diff P3 trials 2019. Over the next few years millions will die from this without help.

If I were to recommend someone investing $100 where to put it "right here - right now" ... there aren't many companies capable of such reward with this low risk. However ....DYOR.