GlobeNewswire
Preclinical data published in Molecular Therapy Nucleic Acids demonstrate that WVE-004 potently reduces C9orf72 transcriptional variants and poly(GP) dipeptide repeat proteins in mice for at least six months while maintaining C9orf72 protein levels Recently reported clinical data from ongoing Phase 1b/2a FOCUS-C9 trial of WVE-004 suggest these preclinical data translate in the clinic CAMBRIDGE, Mass., April 25, 2022 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd. (Nasdaq: WVE), a clinical-stage gene