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Taiwan Liposome Company, Ltd. (TLC)

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4.9300-0.0100 (-0.20%)
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Previous Close4.9400
Open4.9700
Bid4.0000 x 800
Ask6.4000 x 800
Day's Range4.8600 - 5.1201
52 Week Range2.4800 - 12.6500
Volume32,565
Avg. Volume26,100
Market Cap248.854M
Beta (5Y Monthly)0.83
PE Ratio (TTM)N/A
EPS (TTM)-0.5060
Earnings DateN/A
Forward Dividend & YieldN/A (N/A)
Ex-Dividend DateN/A
1y Target Est12.00
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  • TLC to Present at Upcoming Virtual Investor Conferences
    GlobeNewswire

    TLC to Present at Upcoming Virtual Investor Conferences

    SOUTH SAN FRANCISCO, Calif. and TAIPEI, Taiwan, March 02, 2021 (GLOBE NEWSWIRE) -- TLC (Nasdaq: TLC, TWO: 4152), a clinical-stage specialty pharmaceutical company developing novel nanomedicines to target areas of unmet medical need, today announced that the Company’s management team will be presenting at the following virtual investor conferences: HC Wainwright & Co Global Life Sciences Conference (March 9-10, 2021)Presentation: on-demand starting 7am ET, Tuesday, March 9, 2021 Oppenheimer 31st Annual Healthcare Conference (March 16-17, 2021)Presentation: 8am ET, Wednesday, March 17, 2021 The management team will also be participating in one-on-one meetings during the conference. The corporate presentation will be available on the TLC website at www.tlcbio.com in the Investors section, under News & Events. About TLC TLC (NASDAQ: TLC, TWO: 4152) is a clinical-stage specialty pharmaceutical company dedicated to the research and development of a diverse, wholly owned portfolio of novel nanomedicines that maximize the potential of its proprietary lipid-assembled drug delivery platform (LipAD™), including BioSeizer® sustained release technology and NanoX™ active drug loading technology, which are versatile in the choice of active pharmaceutical ingredients and scalable in manufacturing. Cautionary Note on Forward-Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are not guarantees of future performance and involve a number of risks, assumptions, uncertainties and factors, including risks that the outcome of any clinical trial is inherently uncertain and product candidates may prove to be unsafe or ineffective, or may not achieve commercial approval. Other risks are described in the Risk Factors section of TLC’s annual report on Form 20-F for the year ended December 31, 2019 filed with the U.S. Securities and Exchange Commission. All forward-looking statements are based on TLC’s expectations and assumptions as of the date of this press release. Actual results may differ materially from these forward-looking statements. Except as required by law, TLC expressly disclaims any responsibility to update any forward-looking statement contained herein, whether as a result of new information, future events or otherwise. CONTACT: Contact Dawn Chi / Corporate Communications / dawn@tlcbio.com

  • TLC Reports Fiscal Year End 2020 Financial Results and Provides Business Update
    GlobeNewswire

    TLC Reports Fiscal Year End 2020 Financial Results and Provides Business Update

    SOUTH SAN FRANCISCO, Calif. and TAIPEI, Taiwan, Feb. 05, 2021 (GLOBE NEWSWIRE) -- TLC (Nasdaq: TLC, TWO: 4152), a clinical-stage specialty pharmaceutical company developing novel nanomedicines to target areas of unmet medical need, today announced financial results for the fiscal year ended December 31, 2020 and provided a business update. “In the tumultuous year that was 2020, we were fortunate enough to have achieved early patient enrollment in the Phase II clinical trial of our postsurgical pain program before COVID-19 began its spread to the United States,” commented George Yeh, President of TLC. “And in the midst of the pandemic, we managed to complete full patient enrollment in the pivotal trial of our osteoarthritis pain program and continue the global expansion of Ampholipad™, all while initiating a clinical trial for inhalable liposomal hydroxychloroquine as a potential treatment for severe lung diseases such as COVID-19. We hope the application of our proprietary technologies can help to put an end to the pandemic. To resonate with the name of our pivotal trial for our osteoarthritis pain program, EXCELLENCE, we will continue to strive for excellence in this very important year to provide the most benefits for patients, physicians and stakeholders alike.” Clinical Pipeline Update and Upcoming Milestones Following the completion of patient enrollment, 504 patients have received their first injection of TLC599, dexamethasone sodium phosphate or normal saline in EXCELLENCE, the Phase III pivotal clinical trial of TLC599 for symptomatic knee osteoarthritis. Majority of the patients who are due for Week 24 have received a second injection of either TLC599 or placebo. The multi-center, randomized, double-blind, active comparator- and placebo-controlled pivotal study is evaluating the efficacy and safety of a single, as well as a repeat, dose of TLC599 in patients with knee OA across 41 sites in the United States and five sites in Australia.Preparations for pivotal studies of TLC590 for postsurgical pain management are underway, with planned End-of-Phase-2 meetings to occur in 2021 with the United States Food and Drug Administration (FDA) on the design of the clinical trials and production preparations.Published peer-reviewed manuscript in Clinical and Translational Science Journal, presenting the feasibility of applying TLC’s inhalable liposome technology to drugs for direct delivery to – and extended release in – the lungs, as endorsed by key opinion leaders in respiratory therapies. A Phase I randomized, vehicle-controlled, blinded study evaluating the safety, tolerability, and pharmacokinetics of TLC19 (inhalable liposomal hydroxychloroquine) in healthy volunteers is ongoing. Corporate Highlights Completed US$15 million financing for InspirMed™ Inc., a newly established subsidiary that specializes in the development of inhalable liposome formulation programs, such as TLC19, for severe acute and chronic pulmonary diseases. The strategic move to partition lung disease programs from TLC will allow TLC to maintain focus on its current pipeline of liposomal injectable formulation programs, including TLC599 and TLC590.Commercialization of Ampholipad™ advancing smoothly, with a non-binding term sheet for commercialization in a specified territory in Latin America recently signed and review of the formal agreement underway. In Asia, China’s National Medical Products Administration is reviewing the Marketing Authorization Application of the generic liposomal amphotericin B drug. Worldwide discussions for partnership opportunities are ongoing.Held investor conference and attended JP Morgan Healthcare Conference. The management team of TLC presented the latest company updates during the virtual investor conference hosted by KGI Securities, as well as at JP Morgan Healthcare Conference, the largest annual biotech event in the world, which was also conducted virtually due to the COVID-19 pandemic.Expanded global intellectual property protection to 257 patents, with 160 patents granted and 97 applications worldwide as of December 31, 2020. Fiscal Year End 2020 Financial Results Operating revenue for the fiscal year 2020 was NT$101.9 million (US$3.6 million), a 51.3% decrease compared to NT$209.1 million (US$7.0 million) in the fiscal year 2019. Operating expenses for the fiscal year 2020 was NT$1,113.3 million (US$39.6 million), an 8.4% increase compared to NT$1,026.8 million (US$34.3 million) in the fiscal year 2019. Net loss for the fiscal year 2020 was NT$983.3 million (US$35.0 million), compared to a loss of NT$807.5 million (US$27.0 million) in the fiscal year 2019, or a net loss of NT$12.42 (US$0.44) per share for the fiscal year 2020, compared to a net loss of NT$12.32 (US$0.41) per share for the fiscal year 2019. The Company’s cash and cash equivalents were NT$1,342.7 million (US$47.8 million) as of December 31, 2020, compared to NT$1,023.9 million (US$34.2 million) as of December 31, 2019. Financial Summary Selected Consolidated Balance Sheet Data December 31, 2019 December 31, 2020 NT$000 US$000 NT$000 US$000 Cash and cash equivalents and time deposit $1,023,874 $34,232 $1,342,667 $47,816 Total current assets 1,095,614 36,631 1,431,977 50,997 Total assets 1,385,978 46,339 1,749,461 62,303 Total current liabilities 556,697 18,612 348,127 12,398 Long-term borrowings 55,508 1,856 469,076 16,705 Total liabilities 664,068 22,202 886,134 31,557 Total equity 721,910 24,137 863,327 30,746 Selected Consolidated Statements of Operations Data Year ended December 31, 2019 2020 NT$000 US$000 NT$000 US$000 Operating revenue $209,140 $6,992 $101,928 $3,630 Operating expenses General and administrative expenses (166,377) (5,562) (145,769) (5,191)Research and development expenses (860,419) (28,767) (967,503) (34,455)Total operating expenses (1,026,796) (34,329) (1,113,272) (39,646)Loss before income tax (803,402) (26,861) (982,177) (34,978)Income tax expense (4,120) (138) (1,132) (40)Net loss $(807,522) $(26,999) $(983,309) $(35,018)Total other comprehensive loss $(2,782) $(93) $262 $9 Total comprehensive loss $(810,304) $(27,092) $(983,047) $(35,009)Loss per share of common stock Basic and diluted loss per share (in dollars) $(12.32) $(0.41) $(12.42) $(0.44) About TLC TLC (NASDAQ: TLC, TWO: 4152) is a clinical-stage, specialty pharmaceutical company dedicated to the research and development of novel nanomedicines that maximize the potential of its proprietary lipid-assembled drug delivery platform (LipAD™), including BioSeizer® sustained release technology and NanoX™ active drug loading technology, which are versatile in the choice of active pharmaceutical ingredients and scalable in manufacturing. TLC has a diverse, wholly owned portfolio of therapeutics targeting areas of unmet medical need in pain management, ophthalmology, oncology and infectious diseases. TLC is consistently ranked in the top 5% among all listed companies in Taiwan’s Corporate Governance Evaluations. Cautionary Note on Forward-Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements contained in this press release include, without limitation, statements regarding TLC’s expectations regarding the clinical development of TLC’s product and product candidates, including Ampholipad, TLC599, TLC590 and TLC19, the clinical benefits of TLC’s products and product candidates, the timing, scope, progress and outcome of TLC’s clinical trials and regulatory communications, the timing, scope, progress and outcome of TLC’s collaborations and partnerships, the commercialization of Ampholipad, how sufficient cash and equivalents will be to fund operations, the anticipated timelines for the release of clinical data and progress of TLC’s manufacturing capabilities. Words such as "may," "believe," "will," "expect," "plan," "anticipate," "estimate," "intend" and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) are intended to identify forward-looking statements. These forward-looking statements are not guarantees of future performance and involve a number of risks, assumptions, uncertainties and factors, including risks that the outcome of any clinical trial is inherently uncertain and product candidates may prove to be unsafe or ineffective, or may not achieve commercial approval, and delays or disruptions on our business or clinical trials due to the COVID-19 pandemic. Other risks are described in the Risk Factors section of TLC's annual report on Form 20-F for the year ended December 31, 2019 filed with the U.S. Securities and Exchange Commission (the “SEC”) as well as subsequent filings with the SEC. All forward-looking statements are based on TLC's expectations and assumptions as of the date of this press release. Actual results may differ materially from these forward-looking statements. Except as required by law, TLC expressly disclaims any responsibility to update any forward-looking statement contained herein, whether as a result of new information, future events or otherwise. CONTACT: TLC Contact: Dawn Chi Corporate Communications dawn@tlcbio.com

  • TLC Announces Completion of US$15 Million Financing for Subsidiary InspirMed Inc.
    GlobeNewswire

    TLC Announces Completion of US$15 Million Financing for Subsidiary InspirMed Inc.

    SOUTH SAN FRANCISCO, Calif. and TAIPEI, Taiwan, Jan. 04, 2021 (GLOBE NEWSWIRE) -- TLC (Nasdaq: TLC, TWO: 4152), a clinical-stage specialty pharmaceutical company developing novel nanomedicines to target areas of unmet medical need, announced today that its subsidiary, InspirMed Inc., has completed a round of financing, raising US$15 million in cash from strategic investors in exchange for subsidiary equity. InspirMed is a newly established subsidiary of TLC specializing in the development of inhalable liposome formulation programs, such as TLC19 for the treatment of Coronavirus disease 2019 (COVID-19) as well as other programs for severe acute and chronic pulmonary diseases. The strategic move to partition lung disease programs from TLC will allow TLC to maintain focus on its current pipeline of liposomal injectable formulation programs, such as TLC599 for osteoarthritis pain and TLC590 for postsurgical pain, while instilling to InspirMed funding designated for use in the development of inhalable drugs.Long before the emergence of COVID-19, TLC had already begun plans to apply its unique and proprietary technology platforms to lung diseases. TLC’s inhalable liposome formulation first made its public debut at the 2019 International Society of Aerosols in Medicine (ISAM) conference, in an abstract titled “Inhalable Liposomal Nintedanib Formulation for Enhanced Treatment of Pulmonary Disease”, where a proprietary inhalable liposome formulation of nintedanib, a drug commonly used in the treatment of idiopathic pulmonary fibrosis, was found to have sustained release capabilities after being delivered directly to the lungs, avoiding clinical gastrointestinal side effects and requiring less frequent dose administration. The inhalable liposome drug was also found to be less toxic than the free drug. However, as the TLC’s funds were intended for the development of its main pipeline of injectable formulations, with no additional funding available for new programs, the development of inhalable formulations was deferred.With the COVID-19 pandemic this year redacting the world into a state of panic, TLC aspired to make a difference, and investigated the idea of encapsulating hydroxychloroquine, which has shown antiviral effects toward the SARS-CoV-2 virus, into TLC’s proprietary liposome formulation, using only ~1% of the oral dosage needed.  TLC19 Hydroxychloroquine Liposome Inhalation Suspension was thus incubated, with Phase I clinical trial currently taking place in Taiwan and Australia. With the demand for inhalable products heightening, TLC established a subsidiary, allocating its inhalation technical expertise for financing by strategic investors in order to raise funds needed for the expedited research and development of TLC19 and other inhalable programs.“We are happy to have kicked off 2021 with the completion of financing for InspirMed,” said TLC President George Yeh. “This milestone marks a fresh start to a new year, a year in which we hope to see breakthrough development in both our injectable as well as inhalable formulation programs. By working together, we aspire to effectively control the pandemic so that people around the world can return to the comfort of a normal way of life, bringing greater good for all.”About TLCTLC (NASDAQ: TLC, TWO: 4152) is a clinical-stage, specialty pharmaceutical company dedicated to the research and development of novel nanomedicines that maximize the potential of its proprietary lipid-assembled drug delivery platform (LipAD™), including BioSeizer® sustained release technology and NanoX™ active drug loading technology, which are versatile in the choice of active pharmaceutical ingredients and scalable in manufacturing. TLC has a diverse, wholly owned portfolio of therapeutics targeting areas of unmet medical need in pain management, ophthalmology, oncology, and infectious diseases. TLC is consistently ranked top 5% among all listed companies in Taiwan’s Corporate Governance Evaluations.Cautionary Note on Forward-Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements contained in this press release include, without limitation, statements regarding TLC’s expectations regarding the clinical development of TLC’s product candidates, the clinical benefits of TLC’s product candidates, the timing, scope, progress and outcome of TLC’s clinical trials, how sufficient cash and equivalents will be to fund operations, the anticipated timelines for the release of clinical data and progress of TLC’s manufacturing capabilities.  Words such as "may," "believe," "will," "expect," "plan," "anticipate," "estimate," "intend" and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) are intended to identify forward-looking statements. These forward-looking statements are not guarantees of future performance and involve a number of risks, assumptions, uncertainties and factors, including risks that the outcome of any clinical trial is inherently uncertain and product candidates may prove to be unsafe or ineffective, or may not achieve commercial approval, and delays or disruptions on our business or clinical trials due to the COVID-19 pandemic. Other risks are described in the Risk Factors section of TLC's annual report on Form 20-F for the year ended December 31, 2019 filed with the U.S. Securities and Exchange Commission (the “SEC”) as well as subsequent filings with the SEC. All forward-looking statements are based on TLC's expectations and assumptions as of the date of this press release. Actual results may differ materially from these forward-looking statements. Except as required by law, TLC expressly disclaims any responsibility to update any forward-looking statement contained herein, whether as a result of new information, future events or otherwise. CONTACT: TLC Contact: Dawn Chi Corporate Communications dawn@tlcbio.com