| 9.02% | % of Shares Held by All Insider |
| 90.98% | % of Shares Held by Institutions |
| 100.00% | % of Float Held by Institutions |
| 353 | Number of Institutions Holding Shares |
| Holder | Shares | Date Reported | % Out | Value |
|---|---|---|---|---|
| Artal Group S.A. | 14,818,300 | Dec 30, 2018 | 22.24% | 571,245,465 |
| Vanguard Group, Inc. (The) | 5,349,143 | Dec 30, 2018 | 8.03% | 206,209,462 |
| FMR, LLC | 4,799,905 | Dec 30, 2018 | 7.20% | 185,036,337 |
| Blackrock Inc. | 4,391,375 | Dec 30, 2018 | 6.59% | 169,287,506 |
| William Blair Investment Management, LLC | 2,535,824 | Dec 30, 2018 | 3.81% | 97,756,015 |
| HS Management Partners, LLC | 2,226,250 | Dec 30, 2018 | 3.34% | 85,821,937 |
| Macquarie Group Limited | 1,451,419 | Sep 29, 2018 | 2.18% | 104,487,653 |
| St. Denis J. Villere & Company | 1,198,916 | Dec 30, 2018 | 1.80% | 46,218,211 |
| State Street Corporation | 1,193,833 | Dec 30, 2018 | 1.79% | 46,022,262 |
| AQR Capital Management, LLC | 1,072,388 | Dec 30, 2018 | 1.61% | 41,340,557 |
| Holder | Shares | Date Reported | % Out | Value |
|---|---|---|---|---|
| Fidelity Contrafund Inc | 1,861,680 | Nov 29, 2018 | 2.79% | 93,121,233 |
| Vanguard Small-Cap Index Fund | 1,190,699 | Sep 29, 2018 | 1.79% | 85,718,421 |
| Vanguard Total Stock Market Index Fund | 1,176,602 | Sep 29, 2018 | 1.77% | 84,703,577 |
| iShares Core S&P Midcap ETF | 1,097,213 | Nov 29, 2018 | 1.65% | 54,882,594 |
| Delaware Group Equity Funds IV-Delaware SMID Cap Growth Fund | 864,275 | Jun 29, 2018 | 1.30% | 87,378,202 |
| iShares Russell 2000 ETF | 863,481 | Nov 29, 2018 | 1.30% | 43,191,319 |
| Fidelity Small Cap Growth Fund | 630,266 | Oct 30, 2018 | 0.95% | 41,660,582 |
| Vanguard Strategic Equity Fund | 583,916 | Sep 29, 2018 | 0.88% | 42,036,112 |
| Carillon Ser Tr-Carillon Eagle Small Cap Growth Fund | 578,118 | Sep 29, 2018 | 0.87% | 41,618,714 |
| Vanguard Extended Market Index Fund | 501,101 | Sep 29, 2018 | 0.75% | 36,074,260 |